Conserved Protein Domain Family
cupin_PA3510-like
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cd02225: cupin_PA3510-like 
Pseudomonas aeruginosa PA3510 and related proteins, cupin domain
This family includes bacterial proteins homologous to PA3510, a Pseudomonas aeruginosa protein of unknown function with a beta-barrel fold that belongs to the cupin superfamily.
Links
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Statistics
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PSSM-Id: 380354
Aligned: 23 rows
Threshold Bit Score: 194.802
Created: 3-Oct-2005
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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metal binding
Feature 1: metal binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:H H E [RH]Click to see conserved feature residue pattern help
Evidence:
  • Comment:The four-coordinate metallocenter usually includes three histidines and one glutamate; however, proteins in this subfamily may bind metal via different amino acids.
  • Citation:PMID 8612079
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                                                                                    # # 
NP_252200     24 CNTRIARYstrkydwnaLKFQADy--dPRFRRAQMRYIGTGGTGvasdmn----tipseHFTFSTMVIPAGheGPPHLHi 97  Pseudomonas aer...
YP_888425     12 MERYVARYgem---kssDKAYVDtl-lPDHEREIFNVIGPGPTEnpgdanlepalpaveGFHLGYIRSQPGkrGALHAHd 87  Mycobacterium s...
WP_093222361  11 MLKCVARRvei---rssHKAYVDtl-lPGHAREIFNVIGPGVTEspsdpnlapalagidGFRLGYIKSKPGtrGALHSHd 86  Variovorax
WP_093222354  12 MLKFVARRsam---rssDKAYVDvl-lPNHGREIFNILGPGVSEnpsdenlkpaisgvpDFNLAYVRNKPGerGALHAHd 87  Variovorax
OUU68500      21 AQRRVVHFdkl---epdWDAFADaq-vEGHCRGQFRLIGTGGSGkpdpn-----alpagGFTLSIMILPPGqgGSAHTHe 91  Alphaproteobact...
WP_028252830  17 MEKNVARFhdl---kpmKMAFVDtv-lPGYEREILSVIGSAVIEnaahqp---aipamgAFNLACVRSKPGarGALHAHp 89  Variovorax sp. ...
ODS73556      18 GQRQVARFrdr---kpdWEAFEDak-lDGFRRAQHRFIGAGGSAkhgdps----aipplGFTLSVMFVPPGqgNAAHTHe 89  Bordetella sp. ...
PPR10339      23 ADRQVAHFsdr---kpdWSAFADal-iDGYRRAQHRFIGNTSGKgddsi------ipagAFTLSVMYVPAGegNAAHTHe 92  Alphaproteobact...
OUU71205      22 CKTXATRNana----rvWALETEi--dKKYARTQRRYLGTSGNVehtdpn----almgaHFTLTVLQQPAGhkQPMHHHd 91  Alphaproteobact...
WP_075594905  11 IQRYATRQf-------dWNAFPSnagyPELSRAQMRMIGSGGSPksgdtt----tlrpeHFTMSLIYKEPGkfAACHAHe 79  Gluconacetobact...

Feature 1           #                                         #                                  
NP_252200     98 dvEEVFFVLrGKLKVVLEKd----gERFETILtdRDVISVPpGVYREEINIGdEDALMCVMLGa---KKPITPTYPPe-- 168 Pseudomonas aer...
YP_888425     88 -tVEVFIPMkGKWIIIWGDe-----GEHQLPLntFDVITIPaGVFRCFKNVGdEEGLMIGMVSstseKPAGRVIWPE--- 158 Mycobacterium s...
WP_093222361  87 -tTEVFIPMsGKWIIVWGDg-----EESQLELniGDVIAVPpGVFRCFKNVSdDEAWMIGILS----GVPGRIIWPEt-- 154 Variovorax
WP_093222354  88 -tTEVFIPMsGRWQIIWGDe-----EEHTLELdeGDVIAIPpGVFRCFKNIGtTEQWMLAILAg---EKHGRLVWPK--- 155 Variovorax
OUU68500      92 -vEEAFFVLeGELTVFFDDed---gKRASTKLkkYDAVSCPaGIPHGFINEGtEDVLMQTMIGt---GKPGPVGFIDdn- 163 Alphaproteobact...
WP_028252830  90 -tVEVFIPMnGRWAVIWGTdanfgqTPNEIELgpGDVVSVPpGVMRCFKNVSeEEATLMAIVG----TLPGRSDAGRvv- 163 Variovorax sp. ...
ODS73556      90 -vEEVFFVLqGFLDVFLEDea---gNRFETRLgpWECVSCPpGVMHGYLNASlEPVYFQVMLGk---SRPGALNYQDeal 162 Bordetella sp. ...
PPR10339      93 -vEEVFFILkGHLTVFFEDes---gKRIERHLgpWDCVSCPaGVIHGYQNDSvEPVYMQVMLGk--gRDPDRMGYADd-- 164 Alphaproteobact...
OUU71205      92 -eEEVFFVLqGRPTIIWEYa----gETVKRQLdkWDMVYNPpGQVHGIINETnEDCFFQVMLGn---PTPERPKYLDpq- 162 Alphaproteobact...
WP_075594905  80 -iEEAFFILsGVLTVGWELe----gEVVEVALgpKDMILNArDIAHGFRNSGiEPVMLSVMVGa---GKPLPPRYLYhpk 151 Gluconacetobact...

Feature 1                   
NP_252200    169 ---hPLASIKR 176 Pseudomonas aeruginosa PAO1
YP_888425    159 ----QVFRQVR 165 Mycobacterium smegmatis str. MC2 155
WP_093222361 155 ---vKNEVRRL 162 Variovorax
WP_093222354 156 ----KVLDQVR 162 Variovorax
OUU68500     164 --iyEEEIAHL 172 Alphaproteobacteria bacterium TMED63
WP_028252830 164 ---wPEEVIRQ 171 Variovorax sp. URHB0020
ODS73556     163 raavAVNPARR 173 Bordetella sp. SCN 67-23
PPR10339     165 ----KLYKNRN 171 Alphaproteobacteria bacterium MarineAlpha11_Bin1
OUU71205     163 --lrRLQAADR 171 Alphaproteobacteria bacterium TMED63
WP_075594905 152 dtsaELAAAFG 162 Gluconacetobacter hansenii

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