Conserved Protein Domain Family
PHA_synth_I

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TIGR01838: PHA_synth_I 
poly(R)-hydroxyalkanoic acid synthase, class I
This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis]
Statistics
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PSSM-Id: 213656
Aligned: 8 rows
Threshold Bit Score: 874.787
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AAA52191      55 LSKNPARMMEMQWSWWQGQIQIYQNVLMRSVAKDVAPFIQPESGDRRFNSPLWQEHPNFDLLSQSYLLFSQLVQNMVDVV 134 Acinetobacter sp.
AAL77053      50 GSQQPWQLIQAQMNWWQDQLKLMQHTLLKSAGQQSEPVITPERNDRRFKAEAWSEQPIYDYLKQSYLLTARHLLASVDAL 129 Aeromonas hydro...
BAA36198      46 FELPRETLDSLQADYQVQWGQLGQKLLT------GQPFS---FDDRRFASGNWS-EPLFGSLAAFYLLNSSFLLKLLDML 115 Pseudomonas sp....
P23608        61 VKIAPAQLGDIQQRYMKDFSALWQAMAEG----KAEATG--PLHDRRFAGDAWRTNLPYRFAAAFYLLNARALTELADAV 134 Ralstonia eutro...
O66392        52 WMSDPKRSFEAQSRLMMGYMGVWAGALQKLSGEKAEPIAKADPKDGRFKDPEWES-PFFDALKQTYLVTSNWAESMVKEA 130 Azorhizobium ca...
CAC85535      48 MTANPAKIFEAQVSYWAQAMTHYIDATHAFAQGTFKPPADPGPKDRRFSNPLWDSHPYFNFIKQQYLIASSSIEEALSKI 127 Rhodobacter cap...
EJH44967      39 AANQPAALLKVQTQWWEQQLQIWQKVVLESKIQS---IMEAEKGDKRFSHEAWQQDPFFNFIKQSYLLFSKTYLDTINAI 115 Vibrio cholerae...
WP_010919256  52 LAAQPDRLMRAQADLFGQYMELWQTAARRAAGEDVAPVVAPAAGDKRFNDPDWASNPMFDLMKQSYLLSSNWLNGLIAEV 131 Caulobacter vib...
AAA52191     135 EGVPDKVRYRIHFFTRQMINALSPSNFLWTNPEVIQQTVAEQGENLVRGMQVFHDDVMNSGKYLSIRMVNSDSFSLGKDL 214 Acinetobacter sp.
AAL77053     130 DGVPQKSRERLRFFTRQYVNAMAPSNFLATNPELLKLTLESDGQNLVRGLALLAEDLERSADQLNIRLTDESAFELGRDL 209 Aeromonas hydro...
BAA36198     116 LIDEKKPRQRLRYLVEQAIAASAPSNFLVSNPDALQRVVETQGASLVTGMQHLASDMNEG----KMRQCDSGAFKVGIDL 191 Pseudomonas sp....
P23608       135 EAD-AKTRQRIRFAISQWVDAMSPANFLATNPEAQRLLIESGGESLRAGVRNMMEDLTRG----KISQTDESAFEVGRNV 209 Ralstonia eutro...
O66392       131 EGLDPHTKHKAEFLVRQLSNAVAPSNFLMTNPELIRETLSSSGENLVRGMKNLAEDLVEGKGDLKIRQTDMSAFEVGRNL 210 Azorhizobium ca...
CAC85535     128 EGLDPVDRRRLEMFSKQIIDMMAPTNFLATNPDALEKAVATEGESLVRGLENLVRDIEANRGDLVITLSDKNAFSVGHNI 207 Rhodobacter cap...
EJH44967     116 EGLDEKAKERILFFSRQMINALSPSNFIATNPELLRLTLEKNGENLIAGLEQLKEDVASSADILKIRMTNNNAFRLGEDV 195 Vibrio cholerae...
WP_010919256 132 DGVDPATKRRVEFFTKMLTDAFSPSNFLISNPAALREVVQTQGQSLVRGMENFAADLERGGGQLAISQTDLAKFKVGENV 211 Caulobacter vib...
AAA52191     215 AYTPGAVVFENDIFQLLQYEATTENVYQTPILVVPPFINKYYVLDLREQNSLVNWLRQQGHTVFLMSWRNPNAEQKELTF 294 Acinetobacter sp.
AAL77053     210 ATTPGRVVQRTELYELIQYSPTTETVGKTPVLIVPPFINKYYIMDMRPQNSLVAWLVAQGQTVFMISWRNPSVAQAQIDL 289 Aeromonas hydro...
BAA36198     192 ANTPGEIVFENHLFQLIHYYPQSETQYRHPVFVVPPSINKYYILDLRPDNSMVRHLLEQGHPVFLMSWRNFDEEHAGTTW 271 Pseudomonas sp....
P23608       210 AVTEGAVVFENEYFQLLQYKPLTDKVHARPLLMVPPCINKYYILDLQPESSLVRHVVEQGHTVFLVSWRNPDASMAGSTW 289 Ralstonia eutro...
O66392       211 ALSPGKVIFETELMQLIQYAPSTPSVKKTPVLIVPPWINKFYILDLTPEKSLIKWMVDQGLTVFVISWVNPDARLADKGF 290 Azorhizobium ca...
CAC85535     208 GTAKGQVVWRNRLMEIIQYEPTTPEVHKTPLIIFPPWINKFYILDLKPQNSLIRWIVDQGFTLFVVSWKNPDRSYADVGM 287 Rhodobacter cap...
EJH44967     196 ANTPGEVVFKNEVFELIQYKPLTEQVAVTPLLIVPPFINKYYILDLREKNSMVRWLVEQGHSVFMISWRNPGAAQAQLNF 275 Vibrio cholerae...
WP_010919256 212 ATAPGKVVYQNDILQLLQFDPTTDTVCEIPLLIFPPWINKFYIMDLRPENSMIRWLTAQGFTVFVASWVNPDQTLAAKTF 291 Caulobacter vib...
AAA52191     295 ADLITQGSVEALRVIEEITGEKEANCIGYCIGGTLLAATQAYYVAKRLKNHVKSATYMATIIDFENPGSLGVFINEPVVS 374 Acinetobacter sp.
AAL77053     290 DDYVVDGVIAALDGVEAATGEREVHGIGYCIGGTALSLAMGWLAARRQKQRVRTATLFTTLLDFSQPGELGIFIHEPIIA 369 Aeromonas hydro...
BAA36198     272 DDLIELGVIDGLQVAREISGEQRLNCVGFCIGGTLLSTALAVLAARGDRE-IASVSLFTTFLDYHDTGPIDIFVDEELVA 350 Pseudomonas sp....
P23608       290 DDYIEHAAIRAIEVARDISGQDKINVLGFCVGGTIVSTALAVLAARGEHP-AASVTLLTTLLDFADTGILDVFVDEGHVQ 368 Ralstonia eutro...
O66392       291 DDYMRDGIFAALDAVEKATGEHQAHTIGYCVGGTLLAVTLAYMAATG-DDRVASSTFLTTQIDFTHAGDLKVFVDEAQLS 369 Azorhizobium ca...
CAC85535     288 EDYVRDGYLAAIEEVKAITGEKQVNAVGYCIAGTTLSLVLSLLEKRK-DKSIKSATFFTTLTDFSDQGEFTPFLQDDFVD 366 Rhodobacter cap...
EJH44967     276 EDYVLEGVVKAVNAIESITGQEQINAAGYCIGGTVLATTIAYYAAKRMKKRIKTASFFTTLLDFSQPGEVGAYINDTIIR 355 Vibrio cholerae...
WP_010919256 292 EDYMVEGIYDAAQQVMTQCGVDRVNTVGYCIGGTLLSVALAHMAARG-DKRINSATFFAAQQDFAEAGDLLLFTNEEWLQ 370 Caulobacter vib...
AAA52191     375 GLENLNNQ-LG-----YFDGRQLAVTFSLLRENTLYWNYYIDNYLKGKEPSDFDILYWNSDGTNIPAKIHNFLLRNLYLN 448 Acinetobacter sp.
AAL77053     370 ALEAQNEA-KG-----IMDGRQLAVSFSLLRENSLYWNYYIDSYLKGQSPVAFDLLHWNSDSTNVAGKTHNSLLRRLYLE 443 Aeromonas hydro...
BAA36198     351 HRERTIGG-VNgp-igLFRGEDMGNTFSLLRPNDLWWNYNVDKYLKGQKPIPLDLLFWNNDSTNLPGPMYCWYLRHTYLQ 428 Pseudomonas sp....
P23608       369 LREATLGG-GAgapcaLLRGLELANTFSFLRPNDLVWNYVVDNYLKGNTPVPFDLLFWNGDATNLPGPWYCWYLRHTYLQ 447 Ralstonia eutro...
O66392       370 VIERRMKE-MG-----YLEGRKMADAFNMLRSNDLIWPYVVNNYLKGKQPFPFDLLFWNADSTRMPAANHSYYLRNCYLQ 443 Azorhizobium ca...
CAC85535     367 GIERQVRL-DG-----VLSSYYMTRTFSYLRANDLIYQPAIRSYMMGESPPAFDLLYWNGDSTNLPGKMAMEYLRGLCQA 440 Rhodobacter cap...
EJH44967     356 AIELQNNA-KG-----YMDGRSLSVTFSLLRENSLYWNYYVDNYLKGQSPVDFDLLYWNSDSTNVAGACHNFLLRELYLE 429 Vibrio cholerae...
WP_010919256 371 SIEQQMDQaGG-----FLPSQSMADTFNALRGNDLIWSFFVSNYLMGKEPRPFDLLFWNADQTRMPKALHLFYLRNFYKD 445 Caulobacter vib...
AAA52191     449 NELIsPNAVKVNGVGLNLSRVKTPSFFIATQEDHIALWDTCFRGADYLG-GESTLVLGESGHVAGIVNPPSRNKYGCYTN 527 Acinetobacter sp.
AAL77053     444 NQLV-KGELKIRNTRTDLGKVKTPVLLVSAVDDHIALWQGTWQGMKLFG-GEQRFLLAESGHIAGIINPPVANKYGFWHN 521 Aeromonas hydro...
BAA36198     429 NDLK-SGELECCGNKLDLRAIDAPAYILATHDDHIVPWKSAYASTNLLS-GSKRFVLGASGHIAGVINPPAKQKRHYWTn 506 Pseudomonas sp....
P23608       448 NELKvPGKLTVCGVPVDLASIDVPTYIYGSREDHIVPWTAAYASTALLA-NKLRFVLGASGHIAGVINPPAKNKRSHWTn 526 Ralstonia eutro...
O66392       444 NNIA-KGLAEIAGVKIDMGKVTIPVYSLATREDHIAPPNSAYIGAGLLG-GPVRFVLAGSGHIAGVVNPPVKHKYQYWTG 521 Azorhizobium ca...
CAC85535     441 DAFT-TEGFELMGERLHVSGVKVPLCAIACETDHIAPWIVSFNGVAQMGsTDKTFILTESGHIAGIVNPPSKDKYGHYTS 519 Rhodobacter cap...
EJH44967     430 NKLVqDKGVKVGGVWIDLDKIKVPSYFISTKEDHIALWQGTYRGALRTG-GNKTFVLGESGHIAGIVNHPDKRKYGYWVN 508 Vibrio cholerae...
WP_010919256 446 NALT-TGKLSLGGERLDLSKVKIPIYVQSSKDDHIAPYRSVYRGARAFG-GPVTFTMAGSGHIAGVINHPDARKYQHWTN 523 Caulobacter vib...
AAA52191     528 AAKFENTKQWLDGAEYHPESWWLRWQAWVTPYT-GEqvPARNLGNAQyPSIEAAPGRYVLV 587 Acinetobacter sp.
AAL77053     522 GAEADSPESWLAGATHQSGSWWPEMMGFIQSRDeGS--EPVPARVPE-EGLAPAPGHYVKV 579 Aeromonas hydrophila
BAA36198     507 nRVTKNPETWFKNAEQHPGSWWNDWFTWLAGHSgERqpAVAHTGNNKyPPLEPAPGRYVKL 567 Pseudomonas sp. 61-3
P23608       527 dALPESPQQWLAGAIEHHGSWWPDWTAWLAGQAgAKraAPANYGNARyRAIEPAPGRYVKA 587 Ralstonia eutropha H16
O66392       522 GPTGGDYDVWLKGAQEHKGSWWPDWAQWFSALH-PDevPAREPGGSAfNPIEDAPGRYVRE 581 Azorhizobium caulinodans ORS 571
CAC85535     520 AAPIADHQVWKAQATYTKGSWWPRWGEWLAGHS-GKkiPARAPGDAThPPLAPAPGTYVSE 579 Rhodobacter capsulatus SB 1003
EJH44967     509 DTLDDSAEDWLETAQHREGSWWVHWNEWLNGFAdGSkvEPYPLGNADyPVLYSAPGEYVKQ 569 Vibrio cholerae CP1042(15)
WP_010919256 524 SELPADVSEWIAGAHEHPGSWWPHWAAWLKARS-GDqvPARDPAKGKlKPLEDAPGSFVLV 583 Caulobacter vibrioides
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