Conserved Protein Domain Family
OMP_CarO

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NF038067: OMP_CarO 
ornithine uptake porin CarO
The outer membrane porin CarO (carbapenem resistance-associated outer membrane protein), found in Acinetobacter, is of clinical interest because of its role in allowing entry of carbapenem antibiotics and its variability from strain to strain. CarO should not be confused with Omp33-36, an essentially unrelated outer membrane protein that is similar in size and that also affects carbapenem susceptibility.
Statistics
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PSSM-Id: 411651
Aligned: 32 rows
Threshold Bit Score: 366.247
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_004864049   1 MKVLKVITIAAALSAvTGAAM-ADSSVVHEK-WAFDGKQLIPSGVRAEVGTTGYGGALLWDVNPYVGLALGYNGGDISWN 78  Acinetobacter g...
WP_004682664   1 MKTLRVMLAAGVLTAiAGTAF-ADEQIVKESaYGL-PSYLAPVSVRAEVGTTGYGGAISYRVNPYVGVTLGYNGGDISWS 78  Acinetobacter
WP_005274138   1 MKALRVMLAAGALTAiAGTAFaADEQVVKESvYAF-PSYLDPVSVRAEVGTTGYGGAISYRVNPYVSLSLGYNGGDISWS 79  Acinetobacter c...
WP_017400849   1 MKALRVLATATVLTAfAGSALaADEIIVTEE-GVSTFSFFKPASVRAEVGTTGYGGAISYNVNPYVGLTLGYNGGDISWT 79  Acinetobacter r...
WP_016660018   1 MKSLHKILAISVLATaAGSAMaADQTVVTDE-GVSTFSFFKPAAVRAEVGTTGYGGAISWSANPYVGVTLGYNGGDISWS 79  Acinetobacter i...
WP_004784551   1 MKALYQLLAVSVLAAtAGSVMaADETIVTDE-GVAEFSFFKPAAVRAEVGTTGYGGAISWNANPYVGVTLGYNGGDISWS 79  Acinetobacter
WP_004892234   1 MKTFAKYFALSVLAAaTTSVMaADEVIVTDE-GVAEFSFFKPASVRAEVGTTGYGGAISWSVNPYVGLTLGYNGGDISWT 79  Acinetobacter
WP_005247539   1 MKSLHNILAVSALALaASSAMaADETIVTDE-GVAEFSFFKPASVRAEVGTTGYGGAISWSANPYVGVTLGYNGGDISWS 79  Acinetobacter
WP_004815163   1 MKTFAKYFALSVLAAaTTSVMaADEVIVTDE-GVAEFSFFKPASVRAEVGTTGYGGAISWSVNPYVGLTLGYNGGDISWN 79  Acinetobacter s...
WP_008307621   1 MKTFAKYFALSVLTAaTTSVMaADEVIVTDE-GVAEFSFFKPAAVRAEVGTTGYGGAISWSANPYVGVTLGYNGGDISWS 79  Acinetobacter s...
WP_004864049  79 DSLKVNGTKYDMDMDNKTAYLNVEMRPWGTNDNRFVKSLYVAAGAAYIDNDYDLSKSISGDNTTRIHGNNYAa-APGTVA 157 Acinetobacter g...
WP_004682664  79 DDLSINGSKYDLDMDNNLTYLNAELYPWGASE-SLARSLYVAAGVAYIDNEYKLDRRISQGRNFTINKTDFN---ADSNI 154 Acinetobacter
WP_005274138  80 DDLKINGSKYDLDMDNKTAYLNAEIRPWGTNPNNFVNSIYVATGVGYLDNDYKLDRRVGQGRNFTVNNTDFN---ATSDV 156 Acinetobacter c...
WP_017400849  80 DDLSVDGTKYDLDMDNNLTYLNAEIRPWA----NW---FYMAAGVAYIDNDYDLSRRIGGGETLSIDGNDYQlaPGATEG 152 Acinetobacter r...
WP_016660018  80 DDISINGSDYDLDMDNNNVYLNAEIRPWA----NW---FYMAAGVAYLDNDYELDRRVRPNEGFSVNGTDFV--AGANGV 150 Acinetobacter i...
WP_004784551  80 DDLSINGSKYDLDMDNNLTYLNAEIRPWA----NW---FYMAAGVAYIDNDYDIDRRVDPERGFTVNGKDFT--AGADGV 150 Acinetobacter
WP_004892234  80 DDLSIDGSKYDLDMDNNLTYLNAEIRPWA----NW---FYMAAGVAYIDNDYDITRRVGAGESFSVNDVPFE--AGPGGA 150 Acinetobacter
WP_005247539  80 DDISVNGTKYDLDMDNNLTYLNAEIRPWA----NW---FYMAAGVGYIDNDYGLEGRTGADGTITVDGNRYQt-VGGTTG 151 Acinetobacter
WP_004815163  80 DDVSVNGTKYDLDMDNNLTYLNAEIRPWA----NW---FYMAAGVGYVDNEYELSKRIGAGDTLRIDGDSYGrlVGGTEG 152 Acinetobacter s...
WP_008307621  80 DDVEVDDVNYDVDMDNNLTYLNAEIRPWA----NW---FYMAFGVGYLDQQYGLLAR-NDGGTIEVNGED------TGLE 145 Acinetobacter s...
WP_004864049 158 TVSGKMKYDNDIAPYLGFGIAPQINKNFGVFAEVGAYYTGNPTADLHTNGNFIpVAGGTNNADADVKTEAQKIESLSKYE 237 Acinetobacter g...
WP_004682664 155 HLKGDMKYDNDIAPYLGFGFAPQVYKNIGVFGEVGAYYTGNPTATLQNVNGGTaTNGSGASLNDEIAKEERNIENKSKYE 234 Acinetobacter
WP_005274138 157 HIAGKMRYKDDIAPYLGVGVAPQVYKNIGVFGEVGAYYTGNPTATLQNVNGGTaTNGNGANLNDEIAKEQGKIQDKARYE 236 Acinetobacter c...
WP_017400849 153 RVNGQLSYKNNLAPYVGIGFSPAITNRWGVFGEIGAYYNGNPSVNLNASGLAPv--TGSPSVGTAIENEERKIREDNEYE 230 Acinetobacter r...
WP_016660018 151 HINGQMSYKNDIAPYVGIGFSPSITDRWGVFGELGAYYTGNPTVQLTATGTTA---NNNADLQNQVDQEANDIRNDNEYE 227 Acinetobacter i...
WP_004784551 151 RLNGQLSYKNNIAPYVGIGFSPAITNRWGVFGELGAYYNGNPRVNLVSEGTVE---ARQGEFEQAVRDEEREIREDNKYE 227 Acinetobacter
WP_004892234 151 RIDGQLSYKNNIAPYVGIGFSPAITNRWGLFGEIGAYYNGNPTVNLTSSGSATsEDGIVADFADQVEREERNIREDNKYE 230 Acinetobacter
WP_005247539 152 RVTGDLSYKNNIAPYVGIGFSPAITNRWGVFGEIGAYYNGNPTVNLASTSNFTpLDPSAPDIDTALRNEEREIRNDNEYE 231 Acinetobacter
WP_004815163 153 RVDGRLDYRNNIAPYVGIGFSPAITNRWGVFGEIGAFYTGNPDVNLTATNLAPv--EGARPVEDAIADEEREIRNDNEFK 230 Acinetobacter s...
WP_008307621 146 RLGYDLDYSNKIAPYVGIGFSPAITNRWGLFGELGAYYAGNPTVTNVNYY------GGTPTDVALVEEHINEVRNDDKYE 219 Acinetobacter s...
WP_004864049 238 WLPVGKVGVSYRW 250 Acinetobacter gerneri
WP_004682664 235 WMPVAKVGVSFSF 247 Acinetobacter
WP_005274138 237 WMPVAKVGVSFKF 249 Acinetobacter colistiniresistens
WP_017400849 231 WLPVAKLGVSFRF 243 Acinetobacter radioresistens
WP_016660018 228 WLPVAKLGVSFRF 240 Acinetobacter indicus
WP_004784551 228 WLPVAKLGVSFRF 240 Acinetobacter
WP_004892234 231 WLPVAKLGVSFRF 243 Acinetobacter
WP_005247539 232 WLPVAKLGVSFRF 244 Acinetobacter
WP_004815163 231 WLPVAKLGVSFRF 243 Acinetobacter schindleri
WP_008307621 220 WLPVAKLGVSFRF 232 Acinetobacter sp. HA
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