Conserved Protein Domain Family
RlaP
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pfam10127: RlaP 
RNA repair pathway DNA polymerase beta family
Family of the DNA polymerase beta superfamily, with closest affinities to the Minimal Nucleotide Transferase clade (MNT). Observed in diverse RNA repair genome contexts centered on both RtcB and Rnl-type (ATP-grasp fold) repair ligases. Members of this family of bacterial proteins catalyze the transfer of nucleotide residues from nucleoside diphosphates or triphosphates into dimer or polymer forms.
Links
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Statistics
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PSSM-Id: 431073
Aligned: 24 rows
Threshold Bit Score: 194.828
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q853S4         16 HEPVQGAFETSHSSS----HHqqi---aldGLIYLSEVGSTLHGVSTDatSDDIDE--MGIAIEPPRCVIGFerfdlyeY 86  Mycobacterium ...
Q2RSZ8         23 GPAAARAVAAFAEAE----GV---------SLPHAALTGPLAWGLPDD--GVSAPVvcACVFIRPAQAYLGL-------V 80  Rhodospirillum...
Q0ATC2         15 HDTILNQLRQIETRE----NV---------RILFAIESGSRAWGFPSP--DSDYDA--RFVYARPRDWYLSL-------E 70  Maricaulis mar...
Q0BVF7         15 RSVIQERLDRIVAEN----HV---------RILLAVESGSRAWGFPSP--DSDYDV--RFVYVRNRDEYLRL-------H 70  Granulibacter ...
Q2SQI3          2 EKRIQETLERIEWEH----DV---------RVLYACESGSRAWGFASR--DSDYDV--RFIYQRPLSHYLSL-------G 57  Hahella chejue...
Q099H0         10 QTRVSGRILDEEASR-----R---------QHLVVSLTGAHAYGFPSP--DSDLDL--KCVHITPTAHLLRLe------Q 65  Stigmatella au...
Q9S235          2 IDALDIDLAPVVAEQ----PF---------PVLFATVSGAHLYGFPSR--DSDVDL--RGAHLLPAADLVGLrepeetrS 64  Streptomyces c...
Q5YSM9          8 SVHGSAEFQRIANQ----------------NTVLRGQVGSGLHGVTTG--ADDRDE--MGVCIEPPEYVIGLdrfeqyiF 67  Nocardia farci...
jgi:Haur_2984  61 RKQFNDPLLGLEQPQlaenRQ---------WIHYRCVVGSRAYGLDTP--ESDTDW--RGFFVPAAAVDWGL-------- 119
Q7ULC4         64 HHDQLVRLSEFKNQFirntTAplmdsglyeRVIYRCVIGSRAYGLDDE--DSDTDR--RGIYLPPAELHWSL-------- 131 Pirellula sp.

Q853S4         87 RT--KPVSVRSQAGDID-RTIYSLRKYAHLLASGNPTVLMPMFAPAD--KLRYVHPlGQVLRENVGHFLSRQTGQRFLGY 161 Mycobacterium ...
Q2RSZ8         81 EP--PDILHLDATDDMPaVVGWDARRVLRMALRSNAVVWEWLASPVIdgPGARADFrEAFLALATRGYARSTLLGHYLGV 158 Rhodospirillum...
Q0ATC2         71 PG--RDVIELPIDGDLD-INGWDIKKALNLLLKPNPVLLEWLSSPIR--YMWDETTcARLKGFAERVAHGPACVHHYFNL 145 Maricaulis mar...
Q0BVF7         71 AP--RDVIETPLLDEID-LNGWDIRKALGLLLKSNAVIGEWMVSPIQ--YCTAHPViERLNDLAGKVLNRHHLAWHYHSM 145 Granulibacter ...
Q2SQI3         58 KR--RDVIELPIVDELD-VNGWDISKALTLLRSGSATLQEWLNSPIV--YSRDVVFlAQMKYVASLSARPVTLFHHYFSM 132 Hahella chejue...
Q099H0         66 RTtpAERLEVVEGVEVD-YSSNELGPVLLGVLQGNGNFVERLLGAHT---LRGSAElESLRPRVRGVL-SRRLHRHYRGF 140 Stigmatella au...
Q9S235         65 RMwdRDGVE------MD-LVTHDLRKFVRLMLRRNGYVLEQLLSPLV---VHTTEAhRELAGHAPGVL-TAHHAHHYRGF 133 Streptomyces c...
Q5YSM9         68 RT--QPEGVRSGAGDLD-LTVYSLRKWARLAAQGNPTVLLLMFIPEQ--EIVVTSHvGRDLQAHPDRFLSRQVAHRFAGY 142 Nocardia farci...
jgi:Haur_2984 120 ----ATVPEQYEFVETQ-EHYWEVQKFLNLLLRANPNALECLYTDMV----EHASPlALELRAMRHKLLTSRIYQSHNSY 190
Q7ULC4        132 ----YGVPEQLENDQTQ-EVYWELQKFIVLALKANPNVLECLYSPIV----EKVTPlGKDLLAMRDAFLSKLVFQTFSGY 202 Pirellula sp.

Q853S4        162 LNRQRSRY----LDPE--RTDsthasrpelveaygwdTKAGYHALRLAIQGAELMKHRTiTLPME--------------P 221 Mycobacterium ...
Q2RSZ8        159 AKAAMNAY----FPDEprEAA----------------RIKYMHTLRALMAVDWILGKNA-PPPPDwarlr----agaslP 213 Rhodospirillum...
Q0ATC2        146 GESLLNRH----IAPKd-QVN----------------LKKYFYIVRPAMALRWVRMHADiIPPMNfqellagidvsaelT 204 Maricaulis mar...
Q0BVF7        146 GRKSAERW----LTGDe-PVP----------------VKRYFYALRPALALRYLRLHAGkRLPMHvsalmeasdlsrslL 204 Granulibacter ...
Q2SQI3        133 ARKERERL----AAGE---VN----------------AKRYAYMLRTLLAAMWVAEHRT-PPPVRfyelkarmlgggslV 188 Hahella chejue...
Q099H0        141 AQGQLREW----EKTG--FRS----------------TKKLLYVLRTTLTGTHALLTGEvetdlta-------lmdrygF 191 Stigmatella au...
Q9S235        134 AQTQWRLF----ERTG----E----------------LKPLLYTFRVLLTGVHLMRTGEvqphlptl-----veevdaaP 184 Streptomyces c...
Q5YSM9        143 LMSQRDQMlgvkSKKH--TNRpelvd------vygfdTKFAYHMVRLGVQGVELLTTGRiTLPMP--------------E 200 Nocardia farci...
jgi:Haur_2984 191 VLAQFRLLerdlRTHG--SLR----------------WKHVMHLIRLLLSGIHALRHGElrl---------------rhV 237
Q7ULC4        203 VASQFKKMqtdiRNQG--RVK----------------WKHVMHLIRLLLSGTHVLQNGEiiv---------------dvG 249 Pirellula sp.

Q853S4        222 DRREFLLNVRNGQFTKDQV---VTWLESTFVPL---LEHEIEHSTLPEQ---PEWRYINHLLVQ 276 Mycobacterium phage Bxz1
Q2RSZ8        214 AEAAPLLDALEVGPPAERR---HPVLDGWIDSV---FEASRAKGGDLSDd-hPPLAELDGLYRS 270 Rhodospirillum rubrum ATCC 11170
Q0ATC2        205 DALNELLIAKSQSKEVGLAp-rVGVIDAFIEAE---FDWAREVSKGLKSerrNLRDEADGLFRD 264 Maricaulis maris MCS10
Q0BVF7        205 EQINTLIAAKRLTNEQTNGa-rYPELDALIRQE---LAILPESEQTRPPmldRHRREADQLFLD 264 Granulibacter bethesdensis CGD...
Q2SQI3        189 AEVDALLERKAKGNEKEVIk-pVTAIDCFADGQ---FEALE--AVRFDAvdkLDLETIDRVFMQ 246 Hahella chejuensis KCTC 2396
Q099H0        192 AEAGELVAWKRRGERSELSealSERWRGQVGRAfeqLDSARERSVLPEDp--RETGALEAWLLE 253 Stigmatella aurantiaca DW4/3-1
Q9S235        185 VYLPELVAAKAEREHGDAGv-dHARVRADVERLhtvLDEAQAASVLPDAp--TAYDALHDFVVR 245 Streptomyces coelicolor
Q5YSM9        201 PERAWLTELRHGLHTKEE----ALERAADLLAQ---LNHLSLHADLPPE---PDWARINRWLID 254 Nocardia farcinica
jgi:Haur_2984 238 AEHDQLMAIRAGELEWDT----INRWRIALHAE---FEQAYAATKLPIL---PDLAAANAWLLQ 291
Q7ULC4        250 QHRDRLLTIKHGDMPFHA----ADEWRQELQRE---FESAFQTTPLPDR---PDYERANAFLID 303 Pirellula sp.
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