1K0S


Conserved Protein Domain Family
CheW

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cd00732: CheW 
Click on image for an interactive view with Cn3D
CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together with CheA and the methyl-accepting chemotaxis proteins (MCPs), which are involved in response modulation.
Statistics
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PSSM-Id: 238374
Aligned: 26 rows
Threshold Bit Score: 134.236
Created: 6-Mar-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
putative CheA
Conserved site includes 16 residues -Click on image for an interactive view with Cn3D
Feature 1:putative CheA interaction surface
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                      ######                           
1K0S_A       10 EFEVLSFEId-eQALAFDVDNIEMVIEK--SDITPVPKSRHFVEGVINLRGRIIPVVNLAKILGISfd-----eQKMKSI 81  Thermotoga maritima
1172508      34 SWSGIGFRMg-gRFFVAPMGEVGEVLHE--PRYTQLPGVKTWVKGVANVRGRLLPIMDLCGFLGTEls----plRKQRRV 106 Pseudomonas aeru...
1001301       9 RQQFLQFTLepdTNLILPLFQLTEILTVplGQITPIPHMPSWTMGVHNWRGDVLWVIDFGAFLGLTswhlqsgsRTNYRV 88  Synechocystis sp...
1169746      14 EQEFFCFRVg-dLRLGVPSENVLEVLRA--GLLTPLPRTPSFIMGVTGHRGEVLPVLDLLRFLSKGea----riGPRTRL 86  Myxococcus xanthus
1652102      33 GELHLRFYLpsrEEFALPAVSIREVMQQepDRITPIPNASPLLLGTINLRGQVIWVADLGRFLGNNanl--ntdRAEIPV 110 Synechocystis sp...
ZP_00016424  27 EQVFVTIYVe-kQLFGIPVERVQDILIP--EKIARIPLAPPEVAGAINLRGRIVTVIEVRKRLGLKak----ktGGPVMC 99  Rhodospirillum r...
2293002      21 APPVVTFMAg-eALYALPVERVQEILDL--QPVAPLPNAPAHLLGLCDVRGAGVPVVDLRSLLGLPpt----edTGHSRI 93  Rhodobacter spha...
1881576      26 DFKVVSFELg-sDHYLVDIMQVKEIRKS--SNFTYVPNAKKYVAGLDNLRGEIIPIIDLRIMFNLEfn-----kKDIEDI 97  Lyme disease spi...
2688217      13 QLQVAGFKIg-kESYGVSIEHIREIIKVpsEGVYAIPNVPEYIIGIYNLRGSIIPLINLNIKFGVPsisvteedMLLTGY 91  Lyme disease spi...
6225150      20 QFQLVTFQLg-eELYGIDIMGVKEIVKV--QDVRPIPCAPAYVEGIFNLRSEIIPIINLHKRFHLReatlesgdEYLGGF 96  Treponema pallidum
Feature 1           #                  #                                                        
1K0S_A       82 IVARTk-----------------DVEVGFLVDRVLGVLRITENQLDltnvs---dkfgkKSKGLVKTd--------gRLI 133 Thermotoga maritima
1172508     107 LVVEHl-----------------DVFAGLIVDEVFGMQHFPVDTFSeqlppl-eaalqpFIHGVFHRe---------QPW 159 Pseudomonas aeru...
1001301      89 IILNGgvpfdldpsqrrrspgqrNQMLGLVVTEVKDITWCETDQIQsppaasigsdlapYVRGFWVSpp-------gVMY 161 Synechocystis sp...
1169746      87 FVGVTg-----------------SYVAGVVADTVLGLRRIPVADILppplgg--daaaeHLLGVVQAsg------nqEAI 141 Myxococcus xanthus
1652102     111 IAVEDq-----------------ETLLGLAIDSLGNMEWLDTDNLQpandvp--dhiapYVQGEWQIpandapssppQIL 171 Synechocystis sp...
ZP_00016424 100 VTVELg-----------------NELYSLMVDSVGNVQTLPVARIEanpttl-dprwraISRGVVRLd--------gELL 153 Rhodospirillum r...
2293002      94 LVTWVasa-------------gaRHVVGLKTERVIEVTALDEGRMQqmssadmlnwtdtAVMGIGKRn--------gAFV 152 Rhodobacter spha...
1881576      98 MVLKNe-----------------DLLIGVIVDKINNVFSIDSSLIQdphpvlsqdslinYIKGVVDYn--------eKLY 152 Lyme disease spi...
2688217      92 LIVKIk-----------------NKLLGIFVDRVLKVISFDDSRVQeppatl-qtldrkYISGVVKLdead--nlesEYL 151 Lyme disease spi...
6225150      97 VILNVe-----------------DSKLGIIIDRIARVIAVSQEDVQsppqvi-tgigaeYIHGVVRQg--------tSYL 150 Treponema pallidum
Feature 1            ########
1K0S_A      134 IYLDIDKIIEEIT 146 Thermotoga maritima
1172508     160 LVFSPHALAQHQG 172 Pseudomonas aeruginosa
1001301     162 VVLDAQAIVGRLM 174 Synechocystis sp. PCC 6803
1169746     142 NLLNFSKLLQTAR 154 Myxococcus xanthus
1652102     172 RLLDHVALLRSAR 184 Synechocystis sp. PCC 6803
ZP_00016424 154 VVLDVDTFLTFGT 166 Rhodospirillum rubrum
2293002     153 TLLDIDRLMDPSR 165 Rhodobacter sphaeroides
1881576     153 ILLNVFKIFNYGE 165 Lyme disease spirochete
2688217     152 VLIDIAKIFDKCE 164 Lyme disease spirochete
6225150     151 IVLDIHKLFSSKE 163 Treponema pallidum

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