4WJ1,6XZC


Conserved Protein Domain Family
EspB_PE
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pfam18625: EspB_PE 
ESX-1 secreted protein B PE domain
The ESX-1 secretion system is an important virulence determinant in Mycobacterium tuberculosis. ESX-1 secreted protein B (EspB) contains putative PE (Pro-Glu) and PPE (Pro-Pro-Glu) domains, and a C-terminal domain, which is processed by MycP1 protease during secretion. This domain represents the PE domain located at the N-terminal region of EspB which carries the conserved YxxxD/E secretion motif.
Links
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Statistics
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PSSM-Id: 465827
Aligned: 15 rows
Threshold Bit Score: 56.9685
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4WJ1_A         13 PGLERKAHECEStrPE---GPGDAT--KPDELATTASVYSKLXASAAKLKATFAAGDREGERIAAAIRAAAGAYQKIEEQ 87  Mycolicibacter...
EKF25860       12 EDLRNKANMMKN--SPw-kNPFTEPvaPPDQLPSTLAAIENLNTNARTLADFQEWGQAEKNRLADMLIGAADEYERVDRE 88 
KWX23446       10 EELTKRATWISEqaGRw--PTEAPKasPPDDLSSTKTAVDNLNAYGESLQKFTDVSKEESLRLARTLEKVAKAYSDVDEN 87 
WP_019512274    9 DELDATANARSG--AQw--PPVETKaqAPDGLQSSAAAVEKLNANAAALAKYQTIADQQNMTLTHMLHSTASAYRKVDKE 84  high G+C Gram-...
WP_036399447   11 ADLRGLAGAMRA--VFw-yQPDAQAm-PPDQLPLAITATANLNDNAAELAQYQKLAEAQGHRLAEMLDSAAKAYDEVDEK 86  Mycolicibacter...
KQY07075       10 GDLRTKARQVSNveFAdaeGLSSGLq-APDSLPHTKRTIEHLQANADYLAKNQAFAKTEQQRLADTLNSVAKAYDDFDEA 88 
jgi:Mkms_0085  11 ADLRARATTLDEeiTDesqRPT-----PPCGLPFVTASAAGIAAGSDTLRSHLISGNREAERLAAVLSEAADVYQQIDNR 85 
B2HNQ9         12 QEILNRADEVEApmAT---PPTDVPq-APSGLTAANNAAEQLAVSADNVRLYLQAGERERQRLATSLRNAAAAYGEVEDE 87  Mycobacterium ...
KLO48113       12 TEILARAAEVESamTA---APTDVVa-DACALQVAVNAAQQLNLNADNMRTYLAAGYQEWKKLAQSMRNAAKAYGEVDEE 87 
VBC:MMAR_5435  12 SEIVARATEVEApiAD---PPGGAVl-AACALDPAVAGATQLALSAESMRAYLQSGAQARQRLAKFMRDAAKAYEQIDEG 87 

4WJ1_A         88 K 88  Mycolicibacterium smegmatis MC2 155
EKF25860       89 F 89 
KWX23446       88 W 88 
WP_019512274   85 Y 85  high G+C Gram-positive bacteria
WP_036399447   87 Y 87  Mycolicibacterium cosmeticum
KQY07075       89 A 89 
jgi:Mkms_0085  86 A 86 
B2HNQ9         88 S 88  Mycobacterium marinum M
KLO48113       88 S 88 
VBC:MMAR_5435  88 A 88
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