1GHH


Conserved Protein Domain Family
DinI

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pfam06183: DinI 
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DinI-like family
This family of short proteins includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and is positively regulated by the co- protease activity of RecA. Escherichia coli DinI, a LexA-regulated SOS gene product, shuts off the initiation of the SOS response when overexpressed in vivo. Biochemical and genetic studies indicated that DinI physically interacts with RecA to inhibit its co-protease activity. The structure of DinI is known.
Statistics
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PSSM-Id: 428810
Aligned: 22 rows
Threshold Bit Score: 79.6058
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GHH_A           14 PAGAIDALAGELSRRIQYAFPDneGHVSVRYAAA-NNLSVIG-ATKEDKQRISEILQETWESADDWF 78  Escherichia coli
wugsc:CKO_01890  18 PDGAVPALEAELLRRLSQNYEG--VKLTIRRAGA-DGLSILG-GEKGDKQRIEEILQETWESADDWF 80 
wugsc:KPN_01181  15 lPGAREAILNELTKRMQRIFPE--AEVRVKPMMTlPAINTD--ASKHEKELISRTVQEMFEEADMWL 77 
P0A1G3           15 lPGAREIILNELTKRVHQLFPD--AQVKVKPMQA-NALNSD--CTKTEKERLHRMLEEMFEEADMWL 76  Salmonella enterica subsp...
jgi:Rahaq2_1379  15 ipnASEKIEAELVKRVHRLFPE--AEVKVKPMQA-NGLNTHG-ASKQERSQLNQMLEEMFEEADDWL 77 
IEC:ABF-0016414  15 lpNAAEQIKNELAKRIHRVFPD--AEIKIKPMQA-NAINSN--ASKQDKSTINRIIEEMFNEADEWL 76 
CCH:MU9_2984     14 PAHLIQSLEVQLKRRILPLYPD--MQFRIAQSSQ-TTINISGvKSPDDKQSLMDTIQTIWED-DSWM 76 
Q8ZMS6           38 SQSTLDALESELYRNLRPLYPK--TVIRIRKGSS-NGVELTGlQLDEERKQVMKIMQKVWED-DSWL 100 Salmonella enterica subsp...
BAN99305         14 SQSVVDAFREEVDKRVIALFPN--AVVQVRQGSY-NKIEMPGvEVDEDRRRLNDLLQNVWAD-DSWL 76 
WP_011705785     14 PTSTMEALRQELLKQLGEKFPD--LHVRVAPGSA-MALTVSR-ASKEDKELAEAMVQEVWENADSWM 76  Aeromonas
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