Conserved Protein Domain Family
CBS_CbpB

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NF041630: CBS_CbpB 
cyclic-di-AMP-binding protein CbpB
CbpB (c-di-AMP-binding protein B) has two CBS (cystathionine beta synthase) domains (see PF00571). When levels of c-di-AMP are low, CbpB activates RelA, a bifunctional (p)ppGpp synthetase/hydrolase.
Statistics
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PSSM-Id: 469514
Aligned: 86 rows
Threshold Bit Score: 157.607
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_006447515       1 MQEFTLQHEDIARLIIDAEDVACVHPAHSAEHALLVLIKSGYSAIPVVDSAGRVVGIISKTLILDRILGlERIEFEALSQ 80  Alicyclobac...
6_ncbifamImport    1 TAVKELLLEKQETFLVPAENVANVMCLNPLSHAALVLSQVRYSKIPVLDKGDRFVGLIGLTDVVDKMFDlTSVDFEKLNE 80 
30_ncbifamImport   1 QTVEKILLENQENFLVPAENVASVFYNHPLSHALLVLSKVGYSKIPVLDSEDHLVGLISLSNIVERMMDlTGFSMENIEG 80 
39_ncbifamImport   1 KKTRELMEIPETDFIIPADNVATVLYNHPLEHALLVLSKVGYNQIPVLDSDDRLVGLISLANIVNRMMGlTGFDEKLIEN 80 
53_ncbifamImport   1 PAIEKLMKEHEEAMVIPAENVANVMKEHPLEHALLLLSQAGYSTIPVLDKEDHFVGLLSLNDIVKKMLGiNGIDTSNLEE 80 
54_ncbifamImport   1 RAIEELMSEKKDAMMIPAENVANVMVGNPLEHALLVLSKVGYSKIPVLDKGDRFIGLLSLNDVVNKMMDlNGIDTKNLSK 80 
62_ncbifamImport   1 KYTKSLLLENKDSFLIPSDNVATVLYSHPLEHALLVLSKVGYSKIPVLDSSDHLVGLISLANIVDKMMDiDGFNSNVLDG 80 
64_ncbifamImport   1 TTIEKLMLEKAGSFLIPAENVANVMSSHPLNHAVLVLSKVKYSKIPVLDKNDQFVGLISLADIMGKMFSmTSIDLKNLNK 80 
66_ncbifamImport   1 TTVQELLLEDQDNFLVPAENVASLMYSNPLDHALLVLSKVGYSKIPVLDKDDRFVGLIGLNDIVGKMIDlRKIDTDNLAG 80 
69_ncbifamImport   1 EKTEQLLLENQENLVIPAENVATVLYTHGLEHALLVLSKVGYNQIPVLDHEDRFIGVIGLSDVVNKMMGlTGLDVAALEN 80 
WP_006447515      81 FTVADVMRTDFHRIHHDDTFLRALQMSIDAPFLCVEDDDERFVGLLTRHGILAYLNGIIRKNL 143 Alicyclobacillus
6_ncbifamImport   81 FTVADVMEVNVPVIGESWDLEEVLHLLVDASFLPVVDDNQRFKGIITRKEILKAVNHMAHELE 143
30_ncbifamImport  81 LTVADVMEVNVNCIKENDELESMLHLLVDQAFLPIVDDDNVFVGIITRKEILKSVNHLAHEIE 143
39_ncbifamImport  81 LTVADVMEVNVPCVADN-DLEDILHLLVNRSFLPRVDEQGVFCGIITRKEILKAVNHLVHRLE 142
53_ncbifamImport  81 LTVADVMKTDVSVMRPDAELEDVLHLLVDASFLPVLDEEGIFCGIVTRREILKAVNYTFHVFD 143
54_ncbifamImport  81 YTVADVMDTEIDVVKENCDLEDIMHLLVDAAFIPVLDDDGIFKGIVTRREILKAVNHTFHELD 143
62_ncbifamImport  81 LLVSDVMEVNVASLQQEDDLEDVLHLLVEASFLPIVDANNTFEGIITRKEILKSVNHLAHELE 143
64_ncbifamImport  81 YTVSDVMEREVTVIHEDWELEDVLHFLVDTSFLPVVDKYQCFKGIITRKEILKAVNHLAHELE 143
66_ncbifamImport  81 LTVADVMEIGVDYAKEDAQLEDILHLLVNNAFLPIVNSERIFLGIITRKEVLKATNHLVHEME 143
69_ncbifamImport  81 LTVADVMEVNIPCITHN-DVEEILHQLVNRPFLPQVDENGVFTGIVTRKEILKSVNHLAHQLE 142
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