Conserved Protein Domain Family
COG1912

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COG1912: COG1912 
Stereoselective (R,S)-S-adenosylmethionine hydrolase (adenosine-forming) [Coenzyme transport and metabolism, Defense mechanisms]
Statistics
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PSSM-Id: 441516
Aligned: 356 rows
Threshold Bit Score: 123.329
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_004214871   1 MITIASDFG---SPYPAAMKGVLCQRVgasaetgtgagtgtgtatgtdaetdtdtgttpvtsstsptpstttsttpntdT 77 
WP_012410023   2 FICVIADYGt-gDPAFTEVTQRLLMAF----------------------------------------------------P 28 
WP_013178866   2 LVHLIADYGl-gDLAFAEVVQRLKCYL----------------------------------------------------P 28 
WP_013325075   2 LIHLIADYGt-nDPAFAEVSQRLLQHI----------------------------------------------------P 28 
WP_014103708   6 FVRVIGDYGqlgDMAFAEVSDRLDAQLmd-------------------------------------------------iP 36 
WP_015144056   2 FISLIADYGa-nDPAFAEVSQRLLQHL----------------------------------------------------P 28 
WP_015155196   2 QINLIADYGn-gDPAFAEVTQRLLMSL----------------------------------------------------P 28 
WP_015180670   2 LVHIIADYGl-gDLAFAEVVQRIKLYL----------------------------------------------------P 28 
WP_015193170   2 LINLIADYGi-gDPAFAEVTQRLNQKL----------------------------------------------------P 28 
WP_023560684   2 LITVVADYGt-gDLAFAEVRQTFAALV----------------------------------------------------P 28 
WP_004214871  78 TTRLVDIAHDFPRQDIRASAFWLREI-LPYYPP-A--VHLVVVDPGVGTDRDALVVRAGDhILVGPDNGVLLPVARRlA- 152
WP_012410023  29 HAQIHLL--SVPAFSTLATGFWIAQLgLNPGPSdR--LIYHNCAPRQDDPEARRDNEGEGlTYALLSNGVKVVGVNA-Gy 103
WP_013178866  29 DAEAVLT--PVPPFATLAAGFCLAQLgLNDAPPgT--LIYHNVAPRRDEVAARPDNAGERlAFARLPTGVRVVGVNA-Gy 103
WP_013325075  29 DGQIHCL--SVPPFSTLATGFWIAQLgLNPGPDnR--LIYHNCAPRKDDLEARQNNEGEGlTYALLPNGVKVVGVWA-Gy 103
WP_014103708  37 GAHFSVRLSSVPVFDTIATGFMLAQL-AVNSPLgDrhIFYVNTAPRKDKAQARVDNEGEGlVYAKLKNGVRVVAVNS-Gy 114
WP_015144056  29 TAQIHCF--SVPPFSTLATGFWIAQLgLNPGPEsR--LIYHNCAPRQDNPEARIDNEGEGlTYALLPNGVRVVGVWA-Gy 103
WP_015155196  29 TAQIHWV--SVPPFSTLATGFWVAQLgLNPGTAeR--LIYHNCAPRQDDAQPRKDNEGEGlTYVLLPNNVKVVGVNA-Gy 103
WP_015180670  29 DAEPVLT--PVPAFATLAAGFCIAQLgLNQAPPgT--IIYHNVAPREDDQQARTANAGERlAFARLPTGVRVIGVNA-Gy 103
WP_015193170  29 SAQIQCL--SVPPFSTLATGFWNAQLgLNPGAPqR--LIYHNCAPRQDNPEARFDNEGEGlTYVKLKNEVQVVGVLA-Gy 103
WP_023560684  29 QADVSPL--PVPAFDTVSAGFCVAQLaFGAGPAdR--VIYANVAPRQDEDQPREDNAGERlAAARLPSGVLVVAVGS-Ga 103
WP_004214871 153 --------GvdedasvsgttvkgvLEY--YVIdeteleppavagqggpqrsndntaGPASNTFHGRDVFAPAAGDVHEfG 222
WP_012410023 104 tlsfikdyT---------------KELrvVNV------------------------SRGGSQFRSRDVFPPAAAAIMN-E 143
WP_013178866 104 tfsfvrdaA---------------LELrwASV------------------------PAAGSQFRSRDLFPRAVAAIAL-G 143
WP_013325075 104 tlsfikdiA---------------ESIytIKV------------------------SRGGSQFRSRDVFPQGAAAIVQ-G 143
WP_014103708 115 sltlikpfT---------------DSIrlIKV------------------------SAAGSQFRSRDNFPVAVGAIAR-G 154
WP_015144056 104 tlsfiknaA---------------SSIhmINV------------------------SRGGSQFRSRDVFPTAAAALVQ-G 143
WP_015155196 104 tlsfiksaA---------------QTIkiVKV------------------------SRGGSQFRSRDVFPQAAAAIAS-D 143
WP_015180670 104 afsfvrdvA---------------EDLrwAAV------------------------AAEGSQFRSRDLFPQAAGAIAL-G 143
WP_015193170 104 tlsflkeeA---------------LQIntIQV------------------------SRGGSQFRSRDVFPQAAAAIAL-G 143
WP_023560684 104 slsflaaeN---------------IPLyaVKV------------------------ADAGSQFRSRDVFPAAVAGLIA-G 143
WP_004214871 223 LdrrdeLLELPFLERtDSVVDctlpsaTVdddrAEGEVLVVDDFGNAITNVPGRFLTaggrdhdndndnghdrN-HVLAN 301
WP_012410023 144 D-----FSLLGDSLKsEQIPD-------V----PPDRIAWIDGYGNIKTTIGAHTLNlep-----------qsKiVIRIG 196
WP_013178866 144 E-----PDALGDALRpGDVPD-------P----PPSCVAYVDGYGNLKTTIAARTTSlpa-----------gaRvRVRVG 196
WP_013325075 144 D-----VSLLGEQIFpEQIPD-------Y----PGDRIAWVDGYGNIKTTIVADRVElkp-----------qtKvIVRVG 196
WP_014103708 155 D-----ESLLGDDVt-HTVPD------AL----PKNVVVYTDGYGNLKCSIDPKDLDahh-----------geKvTVEIN 207
WP_015144056 144 D-----RSLLGDEISpEQIPD-------F----PTDRVAWIDGYGNLKTTILADSVNlkp-----------etKvVVRVG 196
WP_015155196 144 D-----LSLLGDELDpQQIPD-------P----PSDRVAWIDGYGNIKTTISADRVNlep-----------etKvTIRVG 196
WP_015180670 144 Q-----PDALGEEISsSDIPD-------V----PPNCIAYIDGYGNLKTTIKYDISNgqd-----------geTvRLRMG 196
WP_015193170 144 D-----YSLLGETILpTQISD-------P----PLDRVVWIDGYGNIKTTIPASSLNlpl-----------saKvIVRVG 196
WP_023560684 144 D-----DSLLGEQL---TVPP-------P----PSRSVIYTDGYGNLKTSWYEPPApt-------------gtKvRVRIG 191
WP_004214871 302 GERV--PAVDTFAAVPVGERLATVGSHG-----------YVELDVNQGRGDEAFDLG-VGN-AVVLEF 354
WP_012410023 197 DVVSdaVYSDGSFKVSEGTLAFAPGSSGwptgdsgeplrFLELFLRGGSAWERFGRPrVNQ-QVTRIA 263
WP_013178866 197 EVEReaVASDGSFNVAPGHLAFAPGSSGwrlah--gavrWMELFLRGGSAWEHFGRPdVGS-AIEIEP 261
WP_013325075 197 DLVSdaVYSDGSFQVSEGTLAFAPGSSGwqveg-kpplrWMELFLRGGSAWRRFGKPkVNQ-VVSYQV 262
WP_014103708 208 GREQvaMVGTGIFAVADGEYCLAKGSSGwalpd-gsrmeFAEMVKRGGNASKSFGTP-PGGiKVNWR- 272
WP_015144056 197 DVVSdaIYSDGSFRVPEGTLAFAPGSSGwtlpgekrsvrWVELFLRGGSAWRRFGKPkVNQ-LVTYEP 263
WP_015155196 197 DTVSdaVYSDGSFRVPEGTLAFAPGSSGwqdpn-gkqirWMELFLRGGNAWERFGRPrIDR-VVTYSK 262
WP_015180670 197 EREQdaTKSDGSFAVESGQLAFAPGSSGwvnaq-gdstcWMEIFLRGGNAWESFDCPsVGT-PIQINE 262
WP_015193170 197 DVVSdaIYSDGSFRVPEGTLAFAPGSSGwqtsd-gkkvtWMELFLRGGNAWERFGKPkVNQ-MVTYTI 262
WP_023560684 192 DAEAeaVVSDGVFAVPSGALSFAPGSSGwpttt--grrtCFELLSRGGNAAELFNFPrSGT-PVELV- 255
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