Conserved Protein Domain Family
YBD

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pfam17725: YBD 
YAP binding domain
TEA domain transcription factors contain an N-terminal TEA domain pfam01285 and a C-terminal YAP binding domain (YBD). This entry corresponds to the YBD that binds to the oncoproteins YAP and TAZ. The structure of the YBD shows that it has an Ig-like beta sandwich fold.
Statistics
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PSSM-Id: 435993
Aligned: 5 rows
Threshold Bit Score: 321.351
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EGD82889     203 LRLALDYFSAGITyp--fhQGVHKFFELsgsyhfaDPSMEC--IDLYQIADKFPQ-LEELYRAGP-KEAFFLVKVWADLN 276
CAP23992     267 SKLSLHGFSAYVQcn--ktLERTELVKI-------DNTLEKdhIDISLFYEKYPRlLRELFEKAErKDVFFLAKCWANIN 337
EDQ88370     189 LRLALDYFHAFVDyp--mgAGSHNFVELtgsyhfaDPQMEC--IELSQIADKFPR-LHEAYLQGP-PEAFFLVKFWVDMT 262
XP_024510141 236 SKLVLCGFTAYIRen---tGEQIDIVKInq---isDEPLES--IKFDLIASKFPEeFRVLFDEGP-PDSFFLAKCWGNLA 306
VDN06351     165 SMLTLCGFIAYVEpipsdiTSRVDLVRIpk---laDEPLEAhtFKLEDIAEKYPPvLGELFAAGP-RDGFFLVKCWANID 240
EGD82889     277 ydaeqttqiaHEDDNGNinpqpsdAIFNLATRFESLERMPVECRTSAISLGNVAAEKIQVTEPRYEGGRFLYDLTSGTMC 356
CAP23992     338 ----------VSDDVQN-------CQYAVDSLYASREKFQLKVSTMACSFGSQAVEKIEQYFPIEVDGSYSFMLNNSPMC 400
EDQ88370     263 fdpnq-tmhaMADTETPghgindrSFFGLTCRFESLECMVVEISMCAIQLGKPVVEKIHVEEPIHDQSRYVYAMNRSPLC 341
XP_024510141 307 f--------nLPSEDRKa-----nVIYAVDSFYDSLTKFDISVSTKAITFAKQIVEKVEVYSSVQKDNRYHFALESSPMC 373
VDN06351     241 f--------nLPDDNS--------ALYAVDSFYESTQRFDITVSTKVCSFGKQVIEKVEIYSPVENGRKFNFRLEGSPMC 304
EGD82889     357 EYMTQFISHL-HGVNGVDVINLVLENFAVMQVVRSQTTGEVLFSMACLFEAVPPGTPTgVHVYKL 420
CAP23992     401 DYMVKFIAEL-KKLNAIETMNNVLENFTVLQIVTNSETDELLMVLCFVFEVSQEPEPS-CSVYRL 463
EDQ88370     342 EYMATFAQRL-RALDDIDMMNKVLENFHVTQTVRNQSTGEVLFSFACVFEVAKPGLGCgHHVYKL 405
XP_024510141 374 EYMVDFITKLiKEVSGNELKNRVLENFTVLQVIKNRQTNETVMTIAFMFEVSPDPDPT-SRLYRL 437
VDN06351     305 EYMVKFVAEL-KKLQSHDLMNSVLYNFTVLQVVTNRETKEPLMVIGFVFEVSPVPEST-CRLYRL 367
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