3O4F,1IY9


Conserved Protein Domain Family
speE

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TIGR00417: speE 
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spermidine synthase
the SpeE subunit of spermidine synthase catalysesthe reaction (putrescine + S-adenosylmethioninamine = spermidine + 5'-methylthioadenosine) and is involved in polyamine biosynthesis and in the biosynthesis of spermidine from arganine. The region between residues 77 and 120 of the seed alignment is thought to be involved in binding to decarboxylated SAM. [Central intermediary metabolism, Polyamine biosynthesis]
Statistics
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PSSM-Id: 188048
Aligned: 8 rows
Threshold Bit Score: 410.279
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3O4F_A        13 WHETLHDQ----FGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVL 88  Escherichia col...
Q57761        12 WFTEYHNNn---VALSVRVKDILYREKSGFQEIEIIDTYDFGKALILDNTFQTTERDEFIYHELISHIPLFTHPNPRNVL 88  Methanocaldococ...
P70998         5 WYTEKQTKn---FGITMKVNKTLHTEQTEFQHLEMVETEEFGNMLFLDGMVMTSEKDEFVYHEMVAHVPLFTHPNPEHVL 81  Bacillus subtil...
Q12074        14 WFREISDTmwpgQAMTLKVEKVLHHEKSKYQDVLIFKSTTYGNVLVLDNVIQATERDEFAYQEMIAHLALNSHPNPKKVL 93  Saccharomyces c...
O27950         3 WFFEYYDG----CGLAIKVKKKLYEAEG-VQKVEIYETESMGKMLVIDGKIQLTELDEPFYHEMLVHVPMLSHENPRKVA 77  Archaeoglobus f...
WP_000956207  15 WHETLHDQ----FGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVL 90  Escherichia coli
Q12455        14 WFREINDKsfpgQAFTMTVDSILYEARSEFQDILIFRNKVYGTVLVLDGIVQCTEFDEFAYQEMITHIAMFAHSNPKRVL 93  Saccharomyces c...
1IY9_A         4 WYTEKQTKn---FGITMKVNKTLHTEQTEFQHLEMVETEEFGNMLFLDGMVMTSEKDEFVYHEMVAHVPLFTHPNPEHVL 80  Bacillus subtilis
3O4F_A        89 IIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNaGSYDDPRFKLVIDDGVNFVNQT-----SQTFDVIIS 163 Escherichia col...
Q57761        89 VIGGGDGGTVREVVKHKSVETVDFVELDEKVIEACKKYMPKLS-CEIDNEKVNLIITDGIKYVAET-----EKKYDVIIV 162 Methanocaldococ...
P70998        82 VVGGGDGGVIREILKHPSVKKATLVDIDGKVIEYSKKFLPSIA-GKLDDPRVDVQVDDGFMHIAKS-----ENQYDVIMV 155 Bacillus subtil...
Q12074        94 VIGGGDGGVLREVVKHDSVEEAWLCDIDEAVIRLSKEYLPEMA-ASYSHPKVKTHIGDGFQFLRDY-----QNTFDVIIT 167 Saccharomyces c...
O27950        78 VIGGGDGGALREVLKHN-VERAVLVDIDRNVIDLSRKFLKIDH-GAFEDERVEIAIMDGKEFLRDC------EIFDVIIV 149 Archaeoglobus f...
WP_000956207  91 IIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNaGSYDDPRFKLVIDDGVNFVNQT-----SQTFDVIIS 165 Escherichia coli
Q12455        94 IIGGGDGGVLREVAKHSCVEDITMVEIDSSVIELSRKFLPTLSnGAFDDERLDLKLCDGFKFLQDIgasdvHKKFDVIIT 173 Saccharomyces c...
1IY9_A        81 VVGGGDGGVIREILKHPSVKKATLVDIDGKVIEYSKKFLPSIA-GKLDDPRVDVQVDDGFMHIAKS-----ENQYDVIMV 154 Bacillus subtilis
3O4F_A       164 DCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQ-NGVCFLQQEEAIDSHRKLSHY-FSDVGFYQAAIPTYYGGIMTFAW 241 Escherichia col...
Q57761       163 DCPDPVGPAKGLFEKEFYKNVFKCLNDDGIMVQQ-SESPLYNLDLIQNICRYLKDAgFKIIMPYTYPMPTYPSGFWSFTL 241 Methanocaldococ...
P70998       156 DSTEPVGPAVNLFTKGFYAGIAKALKEDGIFVAQ-TDNPWFTPELITNVQRDVKEI-FPITKLYTANIPTYPSGLWTFTI 233 Bacillus subtil...
Q12074       168 DSSDPEGPAETLFQKEYFQLLNSALTEKGVITTQ-AESMWIHLPIIKDLKKACSEV-FPVAEYSFVTIPTYPTGTIGFMV 245 Saccharomyces c...
O27950       150 DSTDPVGVSDTLFDREFFELARQKCD---VISLQ-SQSPLIQKEYFR--TLLVNSApFERRDVYLSCVPTYPLALWSFII 223 Archaeoglobus f...
WP_000956207 166 DCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQ-NGVCFLQQEEAIDSHRKLSHY-FSDVGFYQAAIPTYYGGIMTFAW 243 Escherichia coli
Q12455       174 DSSDPEGPAEAFFQERYFELLKDALNPNGVVIMQsSENFWLNLKYLHDLKNTAKKV-FPNTEYCYTMVPTYTSGQLGLIV 252 Saccharomyces c...
1IY9_A       155 DSTEPVGPAVNLFTKGFYAGIAKALKEDGIFVAQ-TDNPWFTPELITNVQRDVKEI-FPITKLYTANIPTYPSGLWTFTI 232 Bacillus subtilis
3O4F_A       242 ATDndALRHLSTEIIQARfLASGLKCRYYNPAIHTAAFAL-PQY 284 Escherichia coli K-12
Q57761       242 ASK--KYNPLEVDEARIKeALKDMETKYYDEEVHKGIFLAaPKF 283 Methanocaldococcus jannaschii DSM 2661
P70998       234 GSK--KYDPLAVEDSR----FFDIETKYYTKDIHKAAFVL-PKF 270 Bacillus subtilis subsp. subtilis str. 168
Q12074       246 CSKd-KTCNVKKPLREISdEKEAELYRYYNKKIHEASFVL-PTW 287 Saccharomyces cerevisiae S288c
O27950       224 GGEy-DFSNLEERFERIK-----GKTVHYNPDVHRAAFAL-PEW 260 Archaeoglobus fulgidus DSM 4304
WP_000956207 244 ATDndALRHLSTEIIQARfLASGLKCRYYNPAIHTAAFAL-PQY 286 Escherichia coli
Q12455       253 CSNn-ANIPLNIPQRKIS-EQEQGKLKYYNPQIHSSAFVL-PTW 293 Saccharomyces cerevisiae S288c
1IY9_A       233 GSK--KYDPLAVEDSR----FFDIETKYYTKDIHKAAFVL-PKF 269 Bacillus subtilis
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