Conserved Protein Domain Family
rSAM_QueE_Clost
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TIGR03963: rSAM_QueE_Clost 
putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, clostridial
Members of this radical SAM domain protein family appear to be the Clostridial form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in preQ0 operons species that lack members of related protein family TIGR03365. [Protein synthesis, tRNA and rRNA base modification]
Links
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Statistics
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PSSM-Id: 188478
Aligned: 8 rows
Threshold Bit Score: 380.193
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDY31996   1 MKVVEKFISINGEGRRAGELAVFIRFKGCNLNCSYCDTKWANEPACDYEELSPDDICEYVSETGIKNVTLTGGEPLLQKD 80  Ruminococcus lactar...
EDU37208   8 FKVVERFVSINGEGRRSGQLAIFIRFAGCNLNCSYCDTLWANEKDVSYQLISSKDIYDYIKSQKIKNVTLTGGEPLMQKG 87  Clostridium sporoge...
EDO58623   4 FKVAERFVSINGESVKAGELAVFIRFTGCNLNCSYCDTKWANEADAPYEELTDEEIYDYIKRTGVRNVTLTGGEPLIQKD 83  Clostridium sp. L2-50
EDS17917   4 YKVVEKFISINGEGSRAGQLAAFIRFHYCNLNCSYCDTRYANDSNSNYELLSAQNILDYLKANKVVNVTLTGGEPLLQQN 83  Erysipelatoclostrid...
EEG37992   4 YPVVEKFVSINGEGQKAGKIAAFIRMRGCNLACNYCDTSWANTKDCPCEFLSAEELITWLKEHSIENVTLTGGEPLLTEE 83  [Eubacterium] halli...
EDS20966   4 FKVVETFVSINGEGKKAGRLAMFIRLKGCNLNCSYCDTTWANKRDARCELLTAPQIVERIKEAGVELVTLTGGEPLLDEN 83  Clostridium sp. SS2/1
EDQ97963   2 FNIIEKFVSIDGEGPTAGELATFIRFQGCNLRCSWCDTTYSFDKSEITEVLSAQEIYDYIKSTGVSNVTLTGGEPLFQEN 81  Intestinibacter bar...
EEH90077  10 FPVVEIFDSIDGEGKRTGYMATFVRFAGCNLRCSYCDTAYAWDASQAKEWLSEDNLFQQITAYPWKRVTLTGGEPMLQP- 88  Acidaminococcus sp....

EDY31996  81 IRSLVEKLLNKSDIRVEIETNGAVDIAPLANAfsKEKLSLTMDYKLPSSGCEEKMILSNMEVLRKQDTVKFVSGSVKDLE 160 Ruminococcus lactar...
EDU37208  88 IVELLKVLSKDKELYVEIETNGSVLLDEFLDI--ENSPSFTMDYKLPSSNMENKMALDNFRYLTNKDTVKFVSGSIEDLE 165 Clostridium sporoge...
EDO58623  84 IDKLLLMLAMDEELQVEVETNGSVDIAEFKAL--TDRVAFTLDYKLPGSGMESNMCFSNYNYIDKKDAVKFVSGSIKDLE 161 Clostridium sp. L2-50
EDS17917  84 IDYLID-LLLKNGFSVEIETNGSIDIKPFIKE---TRPIFTLDYKVPSSTMENEMCLNNYQYLTKNDVVKFVVSNLSDLN 159 Erysipelatoclostrid...
EEG37992  84 IAPLIE-ALGTAGFSVEIETNGSVSLNTFDTL--AHRPAFTMDYKCPDSGMENAMNTDNFSLLIPKDTVKFVVSSISDLD 160 [Eubacterium] halli...
EDS20966  84 VSELIGSILMMPKVEIEIETNGSVPIRYYKER--DNRLTMTMDYKLPSSNMEENMCLENMEYLKPWDVVKFVIGSREDLN 161 Clostridium sp. SS2/1
EDQ97963  82 INEVLSLLNDDKNLVVHIETNGAIDILPFKEK--YPNIIFILDYKLASSNMTHLMKLDNLNYVTNKDVYKFVLGSDEDLQ 159 Intestinibacter bar...
EEH90077  89 IETLCR-RLGDAGYEVNIETNGAAAL--FLER--PDRLFYTMDIKSPSSGEKDRMRWENLSLLTADDVLKFVVGSVEDLR 163 Acidaminococcus sp....

EDY31996 161 CAEKIIGKFHLTERCQVFISPVFGSIEPVEIVNFMTSKRMNDVRLQIQMHKVIWNPEERGV 221 Ruminococcus lactaris ATCC 29176
EDU37208 166 KAKEIIKKYNLVNTTNIYISPVFGKINLDTIVEFMKNNKMNGVNLQLQLHKIIWDPNKKGV 226 Clostridium sporogenes ATCC 15579
EDO58623 162 TARDIIHEWALDIKSNVYISPVYGKINPEDIVDFMIENEMNGVKLQLQLHKYIWDPEMRGV 222 Clostridium sp. L2-50
EDS17917 160 KAKEIIDTYDLVNRTKVYFSPVFGKIEPRMIVDYMVKHHLNGINMQLQMHKFIWDVNQRGV 220 Erysipelatoclostridium ramosum DSM 1402
EEG37992 161 KAREICIQYKVAEHCPIFLSPVFGRIEPKEIVEYMIEHHWNEARLQLQMHKFIWPPEQRGV 221 [Eubacterium] hallii DSM 3353
EDS20966 162 RAKEIIERFRLCEKAIVYFSPVFGKIEPEEIVEFMKENKLNKVRFQIQIHKVVWDPDKTGV 222 Clostridium sp. SS2/1
EDQ97963 160 EAYELITKFNLTNKCLVYFSPVFSAIKLEDIVEFMKEKNLNKVRLQVQLHKVIWDPNMKGV 220 Intestinibacter bartlettii DSM 16795
EEH90077 164 YMETILSTYSI--KAQIYVSPVFGKIEPVALVDFVKHHQLSRVCVQVQLHKVIWDPEARGV 222 Acidaminococcus sp. D21
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