Conserved Protein Domain Family
HemYx

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COG3898: HemYx 
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to HemY-type protoporphyrinogen oxidase) [Function unknown]
Statistics
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PSSM-Id: 443105
Aligned: 105 rows
Threshold Bit Score: 265.602
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013385401   5 LLKILTF---VVIVTGVTAGAVWLAEMPGGAVVTLGGVEVTLRPLESVVAIAIVMLLFWAVLRLlglllavLRFINGDDT 81 
AII88449       5 LIKILSF---VAMVMLISFGAGRLMEAQGGVMIQYAGLELSFGALQAALLVLGLLVSFWLVLKLlglvvalLRFINGDET 81 
WP_011383393   2 LLRLIVL---LIFMSPVVLATLWFSDNAGTVQVEWLGWHVDTNVPVLLGILLAVFMLFSGLTRL-------SALVADLPA 71 
WP_011457196   6 LLKIIIF---IAIVVGAVFGITLLTEMDNLGILIIFGREFVITPLLAVIGAVILLLAVWILFKVvgllvafLRMLNGDET 82 
WP_012180075   5 LLKILIF---VTLVAALTFGATLLMETGEQVRISLASTEFTLSPVAAVVLSLVLLGAAYLLFKLaglllatLKFLNGDET 81 
WP_011748284  21 ALKILIF---FAIVLVLTLGAMQLSETGHGLSMVYGSTEYTLGPVQLVIAALVVVLLGWITVRLlglflafLRFLLGDET 97 
WP_025311609   5 LLKVLIF---IAIVGLLTLGVGYLTEMQDAAVLTVAGREFVLTPLIAILGALALLISVWVLFKLvglliatLRFLNGDET 81 
WP_038465746   5 WLSLLFLilkLALAGILVAVAYYLP-GEGNTQLRFVDYIIDIKTGALAAGCVAVIILTFYVFKF-------LAWVKQLPV 76 
WP_039002917   5 LVKILSF---VVLIAALALGAGILAESNEGIRIAVANTEFTLQPLQAAIVSVAFLVLVWLLIKIvglvvavIRFLSGDET 81 
WP_071480995   5 LFKILLF---VGVVVGLAYGAGQLMDSNQTVGLRIFDMEFVLGPMQALIALGVFLAALWLILKLiglsfavLRFMNGDET 81 
WP_013385401  82 AVSRYFSRGRERKGMKALSDSVLALAAGEAKEALARAKVADKYLGAPDVT----HVLLAHTAERAGETHLAEETYKELLT 157
AII88449      82 ALSRYFDRNRERRGFEALSDGLMALASGDGRDAMAKARKADRLLNRPDLT----NLIMAQAAVANGDRQTAKATYKKLLK 157
WP_011383393  72 KLGKSRQARGREKGMLALLAALDAAESGDVGDGRRLGAEAARLLDSPELAarldRLIPRPAAPPAATLRPEPAKGRLFAK 151
WP_011457196  83 ALTRYWSRRSERKGYDALGDAMMALAAGEGRLAIRKAERARKALGRPELT----NLVVAQGAEMVGDKALATETYKAMVT 158
WP_012180075  82 AISRYFMRNRERKGFEALAQGMMALASGEGRVAMAKAARAERYLGRPDLT----QLLTAQAAELSGDRAKATETYKKMLT 157
WP_011748284  98 AINRYFARSRERKGYDALSEGMLAVASGEGKLAQDKAAKAAKFLDKPHVT----DLLAAQAAEVAGDSRKAGEVYRRLLS 173
WP_025311609  82 AISRYFDRRSERKGYEALSEGMMALAAGEGRLAIRKAERAEKYLGRPELT----KLVVAQGAEMVGDRKLATDTYKALVT 157
WP_038465746  77 KLKQQLQERRLRRAKECLLESYIAMSSGELDVALDMATKSKGLDKADVFH----DIFEAQALFMAGEFEQAELKFDKLRH 152
WP_039002917  82 AISRYFDRNRERKGYEALAQGMMALSSGESRVAMAKAARADKYLNRPELT----NLLTAQAAEISGDTQKAEEVYRRLLT 157
WP_071480995  82 AVRRFFMRNREKRGLDALLLALVAQAEGDGKTAIVKAEKAHKLLNRPVMT----NLLVAQAAEMKGNRELAEERYKALLS 157
WP_013385401 158 SDRTRFVALQGLMKQKLTAGDTVTALKLAEAAFKARPENVEVQDVLLRLQAESSDWAGARATLGEKARRGALPRDVYRRR 237
AII88449     158 DPKTRFVGTYGLLQQHLQDGDTEVALKLAEHAFALKPRHGETQDVLLKLQAGQEDWRGVRTTLTAKLKHGSLPKDVHKRR 237
WP_011383393 152 KPPAPPVVEREPPPPVKAAPPPAPVAVVETPAAPADPSAEDA--AAFAAKLRDGEWAAAQACIDATLSAGRLSPALAARW 229
WP_011457196 159 DDRTRFVGVRGLMQQRLDDGDTDTALKLAEKALVLRPKNADVQTTLISLQSRQEDWQGARGTLAAALKAGNVPRDLHRRR 238
WP_012180075 158 DERTKFVGVRGLLHQKLSEGDTETAMALAEKAFALKPRNGEVQDTLLRLQAGDENWAGARKTLAAKLKSGDLPRDVHKRR 237
WP_011748284 174 DPRTRFVGIRGLMRQKLDEGDTVTALKLAEKAYALKPKHAEVQDTLLQLQTRQGDWKGARAVLKDKRQQGQLPKDVHIRR 253
WP_025311609 158 DDRTRFVGVRGLMKQKLEDGDTDTALELGKRALVLRPKNEEVQTKLLDLQARSEDWQGARQTLAAALKSGNIPRDMHKRR 237
WP_038465746 153 CKKTKFLGLRGLISMRKKQNRQEETRLLLIEALKDRPHSVWVLKELLDHNLKHLEFDKANTVVEQLRITGHLDKQKSHRY 232
WP_039002917 158 DERTRFVGVRGIMKQKLAQGDTVTALALAEKAFALKPRHTETQNTLLQLQTEKHDWQGARRTLKSQVKTGAIPRDVYKRR 237
WP_071480995 158 DNRSRFVAVQGLLRSKLDQGDKEKARALAAKALEMQPAHEPTQNALLQMQTEAEDWGGARKTLLLKKTSGSLPRDVWRRR 237
WP_013385401 238 DAVLALSEAQAVfDDKVPIDARERAIEANRLSPDLVPAAVMAARSYIKDGNPRYATRVLRKAWEVQPHPDLAEAFAEIMP 317
AII88449     238 DAVFALSQSRDLrAEGKLEEAQIYAVEANRLAPGLVPGALLSAEGHREQNNVKQASRILRAAWQLAPHPDLAAGFAALAP 317
WP_011383393 230 RAVVLEGQACLD-SQDDPARSLRLAREALAADPGFLPAALHVLRQEVSEGRRSEAEAVLAAVWRSAPARILLETCSPLWR 308
WP_011457196 239 DAVLALAHARDAmAEGQVVTATRDVAEANRLAPGLVPAAVMSTRLAVEAGNKRQAAKTIRKAWDQAPHPDLAAAFALIEP 318
WP_012180075 238 DAVLAYSEAADAvEAGKMDKAEAHANEANRLAPGLVPSAALAARMAIRAGKQRQATKLLRKAWELNPHPELAAAYAEIVP 317
WP_011748284 254 DAVLALKEASEVlAHGNSISAREAAISANRASPDLIPAAVLAARSYIAQNDPRNAGRVLQKTWSVRPHPSIAATYAEIVP 333
WP_025311609 238 DAVLALAHAREAmAEGKVAEATREANAANAMAPGLVPAAVMAARLAIADGKPRVATKILKTAWDSTPHPDLAAAFAAIAP 317
WP_038465746 233 QALVAWLRALQAkRSGDQSAFETYAHQSLKLDPKLTAATLELAQYYQGQGQSSKCIKTLERGYENLPHLDYLGVFQAVFS 312
WP_039002917 238 DAVLALSEVSILlDETSTIEAREAAIATQKQSPDLIPASVLAADVYIEQGKPKLAARLLKKAWAAQPHPDLAAAFARIDP 317
WP_071480995 238 DAILALQDADKLaAQGELQRAREAAIEANRLSPDLIPAAVAAAQALSAQGKGSYAAKVIKRAWKAQPHPDLAAAFAAIEK 317
WP_013385401 318 DERPDQRLARFETLTNLRTDHAENKMLRAELLIANGDFPAARRALGELVEgADATSRSLALMAAIERGMGAD-ESVVRGW 396
AII88449     318 DEASVARLKRFGQFTKGTESHPETKMLMAELYVAMADFDAARQALGDLAK-TDPTMRALTILAAIERGDGAD-DQSVRRL 395
WP_011383393 309 EDDAESRLKRLEVLAEWAPHDPEGHLAAGEAAVAAAKWGVARRHLMAALK-IAPDALGCRLMAEIEDKEPGG-AERAEIW 386
WP_011457196 319 DETPALRLRRFRPLLGKHPTHPEVKMLEAELHIANEDFPAARKALGDLAE-SAPTARSLTIMAAVERGEGSP-DRIVRGW 396
WP_012180075 318 DETAAARIKRFEALVKPNPNHDESRLLMAELFIAAEDFPAARKAMGDLYE-TKPNARSLTIMAAVERGEGSD-DAIVRAW 395
WP_011748284 334 DEKPAARLRRFEDLMRQNPDHEETRLLRAELLLAAEDFPGARRALGDLAE-KHPTVRSLSILAAVERGEGGD-DAVVRGI 411
WP_025311609 318 DESPSDRLKRFRPLLAKHASDPESKMLEAELHIAAEDFPAARRALGDLAE-TLPTARSLTIMAAIERGQGAE-DRVVRAW 395
WP_038465746 313 QETTLDQYRLVENIIGKKLDHRASHVILATLAIAAKLWGQARLHINILNE--RPTQLVYSLLADLERAEHPNhSQTISDY 390
WP_039002917 318 NEDAKARLKRFEALTNQRTGHPETIMLLAELLISAEDFPTARRKMGTLAE-TSPSSRSLALMAAIERGEGAD-DATVRGW 395
WP_071480995 318 DETPKQRKTRFEKLLRMHPNAAETKLLRAELLISAEDFPGARRALGDLYE-SDPTVRALTIMAAIERGEGAD-DAVVRGW 395
WP_013385401 397 LTRALTAPRGPQWVCGQCGKVHAQWLPVCASCHGFDTLAWTTPPASD--FAMPggaAMLPLIVGapvapvdlsgdvveqa 474
AII88449     396 LTQAISAQRDPQWICDNCGHVHHDWEPVCLNCEAIDSIAWKRPPMSE--AVSP---DMLPLIVGhmars----------d 460
WP_011383393 387 RRREREAPAAPTWVCEACGATSGSWAPYCSACAAGAAIQWTRPAHKP--ENPPapaSVPPSAEA---------------- 448
WP_011457196 397 LARAVTAPRGNQWLCDNCGHVHEDWTPVCVNCESFDTLDWAEPRQSE--TSLAgptQMLPLIVGaled------------ 462
WP_012180075 396 LAKAVTASRGPQWTCENCNNIHASWTPVCGNCGAFDSLSWVEPPESE--IALTnsaEMLPLIVGaiad------------ 461
WP_011748284 412 LARALVASRGPQWVCDKCHNVMADWSPTCDSCGGFDTLTWCEPDTPAwgATASngvEMLPLLVGaphgnga------gad 485
WP_025311609 396 LAKAVTASRGPQWICEVDGKAYPEWQPVTD--GGFDTLTWKTAPQSE--AALAgpaQMLPLIVGaledq----------- 460
WP_038465746 391 LKLAVQGMPEGEWVCHNCHTTQLSWNVFCPSCQAFDQITWETQA--------------MPTSSIalik------------ 444
WP_039002917 396 LAKAVTAPRSEAWVCDNCGQVHGVWVPVCTKCNSIDTLSWKTPSEPE--SESTnsaSMLALITEsirn------------ 461
WP_071480995 396 LARALTAKRGPQWVCSKCQHVHASWQAVCDNCGAFDTLEWHDAPDST--GPSAtqtELLPLIVGnlpkp----------- 462
WP_013385401 475 vkpAPTPAPQtk-------------------------------------------------vEDAEEEVILp--pPPDve 503
AII88449     461 edfPPLLEPEd---------------------------------------------------LSQADASAVki-aADDa- 487
WP_011383393 449 ---PPA---------------------------------------------------------------------PAE-- 454
WP_011457196 463 qsdAPEAAPEag-------------------------------------------------pDAEEEAEILd----DT-- 487
WP_012180075 462 qsaKKDPEEe----------------------------------------------------VIVPDVVDIt---PTE-- 484
WP_011748284 486 vpaPPVPAAQaratppvpqpeapapeagpveiadvspgmvpresdyrrvspgvggvepamtvTDPEPAAVApp-aPEPlr 564
WP_025311609 461 ----------------------------------------------------------tpgsAAAQEAEIVedaaPAQaa 482
WP_038465746     --------------------------------------------------------------------------------    
WP_039002917 462 ddlDDEEDV--------------------------------------------------------QDAEIVp----DE-- 479
WP_071480995 463 ----------------------------------------------------------vetsDAVVEGDIVe---TAD-- 479
WP_013385401 504 ---lP------------EET 508
AII88449     488 ----P------------LKE 491
WP_011383393 455 ----Prvs------riqAES 464
WP_011457196 488 ----P------------AEP 491
WP_012180075 485 ----T------------GDD 488
WP_011748284 565 e-pvPgvqgdilpvrpdVEP 583
WP_025311609 483 dtatPg----------dAQP 492
WP_038465746     --------------------    
WP_039002917 480 ----P------------KTS 483
WP_071480995 480 -----------------VEN 482
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