Conserved Protein Domain Family
CxxCxxCC
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pfam03692: CxxCxxCC 
Putative zinc- or iron-chelating domain
This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.
Links
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Statistics
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PSSM-Id: 308985
Aligned: 35 rows
Threshold Bit Score: 36.4487
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q9HSD2  29 ECTR----C-GACCKseaddPHTATVFPDEVRDVQAAAGAETDRDWRDVARpmpygldedgagetfewalqadSCGDCTF 103 Halobacterium salinarum
O59556  18 KCKF----C-LDCCK-----GRHVYLTLNDIKRLIDAGYDPQDFLTISIEDgkirfv-----------lsvreWDLGCVF 76  Pyrococcus horikoshii
Q9HXX6  19 ACKPg---C-HDCCG-------PVTASSEEMARLPVKSEAEHDAALAEW---------------------------NCVH 60  Pseudomonas aeruginosa
O28834   4 NCFDgssfC-GKCCY-----ETEMPLTEEDIARIEALGYSRSDFTVKDGEIvrl-----------------rnVNGKCFF 60  Archaeoglobus fulgidus
O27978   7 VCSR----CgGKCCI-----DAKPPITERRLRILLDSGISLELFDFEEYTHpk------------------mkENGYCVF 59  Archaeoglobus fulgidus
Q55439   5 YCMQg---C-GACCN----------LTPEDRPELAEYLAPEELTLYHSLVG----------------------ADGWCVN 48  Synechocystis sp. PCC...
O25459 336 PCTS----C-GLCCK-----------NIAGIIELIGFDA----------------------------------GNGVCKF 365 Helicobacter pylori
Q9PBV8  72 ACRYg---C-SACCH------YKVDLLPIEAELIAISLGQAPLPLPTTFQNg---------------------HGKRCPF 120 Xylella fastidiosa
O28384  13 ACYPgi-kCfNECCK-----NLNLALTPYDVLRMARGLKITTTEFLEKYTSrhvgmatg------lpvvvlrmVDERCPF 80  Archaeoglobus fulgidus
Q58349  16 ECIN----C-AYCCSc---kGWRIYLNYFDRLKLKDYEYAIEPCEGEFKYRlk-------------------vNEKGCVL 68  Methanocaldococcus ja...

Q9HSD2 104 YREDDDgtgACSV-----HGSRPLICQTYPFSvalggts----qpmgeaVDEAGMVRAHECE 156 Halobacterium salinarum
O59556  77 QDPETG---LCKV-----HPHRPLICRIYPFMvskkplgikgekkfeinGKSFWLYYDENCP 130 Pyrococcus horikoshii
Q9HXX6  61 LGPN-----GCEA-----YEERPLICR------------------------LFGTTPNLPCP 88  Pseudomonas aeruginosa
O28834  61 LDSEN----RCRI-----YQHRPEGCRIYPAV-----------------FDGRDVIADRFCP 96  Archaeoglobus fulgidus
O27978  60 FDEKEK---KCLI-----HSIKPETCVAGPFTfdl-----------regKIDIYLKKESICP 102 Archaeoglobus fulgidus
Q55439  49 YNHGDR---LCQI-----YEDRPSFCRVKPDNfarm----------fgiAPAEFDEFASHCC 92  Synechocystis sp. PCC 6803
O25459 366 LDLETN---LCKI-----YESRPLICRIDEAHkkly---------phipLKEFYAKNAEVCN 410 Helicobacter pylori
Q9PBV8 121 LSKNG----QCNI-----YSIRPMACR----------------------RHFMFTNSDYWCN 151 Xylella fastidiosa
O28384  81 VTER-----GCSI-----YAHRPTPCRLYPLArvr-----------vgeEIQYYLLREDFCL 121 Archaeoglobus fulgidus
Q58349  69 LNNN-----LCRIhlekgYEFKPLMCMIFPFScmi------------kwDGTPLLIIKHYCS 113 Methanocaldococcus jannaschii DSM 2661
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