2KFS


Conserved Protein Domain Family
Rv2175c_C

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pfam18367: Rv2175c_C 
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Rv2175c C-terminal domain of unknown function
This is the C-terminal domain of unknown function found in actinomycetes such as M. tuberculosis Rv2175c. Rv2175c has a DNA binding activity and possesses a winged helix-turn-helix fold, furthermore it is identified as a substrate of the PknL kinase.
Statistics
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PSSM-Id: 436442
Aligned: 36 rows
Threshold Bit Score: 83.0478
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2KFS_A                   80 VKSLPGLLTILHDGGYRDTEIMRWLFTPDPSLTitrdgsrdavsnA-RPVDALHAHQAREVVRRAQAMA 147
WP_068894214             68 VKGLPGTLTVLLDAGYDDVEALRWLFTPDETLP------------G-SPVDAIRAGRHTEVKRRAQTLG 123 Planomonospora
WP_034226769             66 VPALPGTLTLLADAGFSDEAAVRWLFTPDETLRglgtg---pvrpS-TPVEALAAGHKTEIRRRAQAEA 130 Actinotalea fer...
KGM15435                 61 VPTLPGTLVLLADAGFSDEEAVRWLFSPDPTLTpvgwp---dgavP-APIDLLAAGQKTEVRRRAQALG 125
WP_043123101             54 VDSLKGTIAVLADAGFSDEELITWLFTPDESLK------------G-RPIDALREGRKTEIRRRAQILA 109 Sinomonas humi
PRJNA293260:AL755_08190  61 VDSLRGTITVLHDAGFDDEEAITWLFTADESLP------------G-RPIDALHEGRKTEIRRRAAALG 116
KZE90670                 60 VTSLRGTVIVLQDAGFSDDELIDWLLTEDESLG------------H-APIESLRAGRKSEVRRIAQALA 115
KQQ51027                 58 VHNLRGTLTLLSDNGFDDEAAMVWMLEDDDAI-------------GtSPIEALRAGRRSEVRRVAQALA 113
EJZ88130                 58 VDGLSGTLTVLQDAGMDLVQATTWLLEGDDTFV------------G-RPIDALKQGRKKQVNSYARSLA 113
Q0RFM5                   23 VKGLPGLLTLLADAGFTDDEALDWLFREDPSLP------------G-TPMQALVENRGKEVKRRAQALA 78  Frankia alni AC...
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