3LM8,3MEL,3CQ9,2OMK,3IHK


Conserved Protein Domain Family
ThiN

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COG1564: ThiN 
Thiamine pyrophosphokinase [Coenzyme transport and metabolism]
Thiamine pyrophosphokinase is part of the Pathway/BioSystem: Thiamine biosynthesis
Statistics
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PSSM-Id: 441172
Aligned: 335 rows
Threshold Bit Score: 127.603
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3LM8_A         2 KTINIVAG---GPKNLIPDLT-------GYTDEHT----LWIGVDKGTVTLLDAGIIPVEAFGDFDSITEQER-RRIEK- 65 
WP_015893704   4 TRILLFAG---GNLGTWAI---------QEIREND----WLVGVDRGALFLVRNGLVPKLSIGDFDSVSSEEM-AEIER- 65 
WP_013118991   5 KRILIFSG---GNLGNWAV---------DEIEQGD----FLVGADRGALFLLQHGIQPDYALGDFDSVTDKEF-AEIKD- 66 
WP_013371460   4 KRAIVFSG---GRLNEEDL---------QQIQPDD----FIIGADKGALFLIEHGITPHVSVGDFDSITSEEQ-EQVKS- 65 
WP_013188840  21 SRCLVVVG---GVQg----LRalcadswDFL-TYE----LVICGDSGQDVARTLGINPDVYIGDFDSSPRPAGqTEFADg 88 
WP_015254606   5 KRIVIFAG---GNLGNDSA---------KFIRPGD----LLIGADSGAARMIELGFVPDLAIGDFDSVSPDEL-ETIRR- 66 
WP_023468760   1 MRAILVCA---GPREEAPDLR-------TFCQPGD----FIVGVDGGVQTIESFGLTCDLTIGDFDSLGYVPEg------ 60 
WP_009256875   6 KRALLFGSvpcGDGA---FLR-------PYL---DgggwTVFCADGGVRNARAAGLRPDYLIGDWDSGGAPEG-D----- 66 
WP_077719429   6 SRVVIATG---GQWGPDDH---------ALIAKDD----FVIGVDGGNDELLQRNITPHLAVGDFDTAQLERV-EALRS- 67 
WP_123040637  10 RRAVIVTG---GRLGDWAL---------DELREGD----YLIGADSGAEFLVSRGLVPDLALGDFDSVPPERL-PAIRE- 71 
3LM8_A        66 ----------------------AAPALHVY-QAEKDQTDLDLALDWALEK-QPDIIQIFGITGGRADHFLGNIQLLYKGV 121
WP_015893704  66 ----------------------LSMHVSSCdPVMKDWTDTEMALTWAIEQ-QPEEIVLLGVLGSRFDHMLANVHLLNKAL 122
WP_013118991  67 ----------------------KCKNLFSCnPVYKDYTDTEMAFNWALAK-RPKEILLLGVTGTRFDHNIANIHLLSKGL 123
WP_013371460  66 ----------------------ASQRMIACdPVHKDLTDTELALEIAMEE-QVDHVLFLGVTGTRMDHTLANVQILVRAM 122
WP_013188840  89 rtrspetlaavpvitpsdavpgDGVEVIVL-PVAKEVTDSEAAVDLAYSR-GYRHIDVIGGLGGRLDHTLGNLGILAKYA 166
WP_015254606  67 ----------------------ISRRTEIVdPVDKDYTDTELAFNRALEL-EPGEIVIAGALGTRFDHSLANVHLLAAAH 123
WP_023468760  61 --------------------------AIVH-PAEKDETDLELALRTVSEKkQFEDTFIIGATGGRLDMTVQNVYLLKRYP 113
WP_009256875  67 ------------------------VPCITL-PVEKDMTDLQAAVDQALEL-DYRELLLCGCTGGRLDHTASNLVLLEWIA 120
WP_077719429  68 ----------------------LGVPVEQL-PRDKDVTDTDYAVTKALQR-QPKEVLLLGAWGTRWDHTLANVNLLERIE 123
WP_123040637  72 ----------------------AARECLAVdAVDKDWTDTELALREAQDR-GYADIRILGGLGTRFDHSLANVHLLRQAL 128
3LM8_A       122 KtnIKIRLIDKQNHIQXFPPgEYDIEKD-ENKrYISFIPFSeDIHELTLTGFKYPLNNCHITLGSTLCISNELIHSRGTF 200
WP_015893704 123 QtgSNCRILDETNEIRLIDR-QSTIEQD-HFD-HISLLPFTpEVTGITLTGFLYPLKDATLRIGDTLGISNLLTEQTGTI 199
WP_013118991 124 KekVPVRLIDEKNEITLIDS-FIEISGN-RFR-YISILPFSyEVKGVTLEGFKYPLHKASLTRGTSIGISNELIEDRATI 200
WP_013371460 123 QhhISCAIMDAHNYIELTES-TLEIQPM-GYT-YTSLIPMTaEVTGIQLEGFMYPLHNATLKMGQSRGVSNKLTAAKGTI 199
WP_013188840 167 HtsARLRWIDGYNMVSLVGPgTHTVPRN-DYR-YFGLIPFDgDVQGLTLAGTRYLVEDFTLVRGSTRGVSNEITAQCATV 244
WP_015254606 124 RrgVRAVVTDDRNEIRLAAGgERLTFRRtDHP-AVSLLPLTpVVTGIALEGFRYPLSGARLEIGQSLGISNVLEADEGAV 202
WP_023468760 114 E----ARLVTKREEVRYLAEgTYTVEAG-SYY-YLSFIPLVp--STLSLSGVKYPLDAHPVPVGGSLTVSNEWCASEAKV 185
WP_009256875 121 DhgGRALLVDADNEVRLLDSgVLRLTNRpCYH-YLSLVPLDrRVTGVTLRGLKYPLTDAVLTRGDTLSVSNEPLGDEVEI 199
WP_077719429 124 RagVRGVMQNYLNRMELVGPgQHVVRRQ-HYH-YMSMIAWQgAVKGIHLSGFRFPLVDATLERMSSLAISNEWIGESGTV 201
WP_123040637 129 ArgGQALLVDEHNEIRLCTg-ECRIEADpRYP-YVSLLPLTeTVTGVTLTGFRYPLTEAVLTLGWSLGVSNVLEADIGNV 206
3LM8_A       201 SFVKGILIXIR 211
WP_015893704 200 TIQTGKLLVVK 210
WP_013118991 201 NIDSGQLLVIR 211
WP_013371460 200 SIKSGLLLVIQ 210
WP_013188840 245 SFTSGRLLMVS 255
WP_015254606 203 TVGEGLLLVIL 213
WP_023468760 186 ELHQGELLMMR 196
WP_009256875 200 CLSAGRALLIR 210
WP_077719429 202 KLREGKLLIIQ 212
WP_123040637 207 TIRGGQVLIIR 217
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