3HJG


Conserved Protein Domain Family
ribazole_cobC

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TIGR03162: ribazole_cobC 
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alpha-ribazole phosphatase
Members of this protein family include the known CobC protein of Salmonella and Eschichia coli species, and homologous proteins found in cobalamin biosynthesis regions in other bacteria. This protein is alpha-ribazole phosphatase (EC 3.1.3.73) and, like many phosphatases, can be closely related in sequence to other phosphatases with different functions. Close homologs excluded from this model include proteins with duplications, so this model is built in -g mode to suppress hits to those proteins. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Statistics
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PSSM-Id: 274461
Aligned: 32 rows
Threshold Bit Score: 160.48
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3HJG_A         8 IYLMRHGKVDAAPGLH--GQTDLKVKEAEQQQIAMAW-KT---K----G---YDVAGI--ISSPLSRCHDLAQILAEQQL 72  Vibrio parahaem...
WP_002075847   3 LYLIRHTTPEIPKGICy-GQTDIPLISDFNSEFQFLLqKI--------N---VVFDLI--YSSPSSRCRKLSEFLNNQYL 68  Leptospira inte...
WP_014224326   3 IYLIRHTSVDVPAGTCy-GQTDVPLKPSFEAEAATVKkEL---D----R---YAFDAV--YTSPLSRCTRLAAYCGYPEA 69  Tannerella fors...
WP_005873573   3 ITLIRHTTPDVPAGICy-GQSDVPLRASFEEEAEVVRrRL---S----G---MDFDAV--YTSPLSRCARLAHFCGYPD- 68  Porphyromonas g...
WP_010993040   3 VILIRHTSVDVPKGVCy-GQTNVPLRDSFEEEASITAqQL---Q----N---DVFDAV--FTSPLSRCTRLADHCGYPD- 68  Bacteroides fra...
WP_011467115   2 LYFIRHTQIKLTEGTCy-GRLDIPLAGSYFEERALVKaRL---ArllgD---TPAEQIefHTSPLGRCEALAQYLA--VG 72  Saccharophagus ...
WP_011002318   3 IILIRHARPAMAAGLCy-GRTDLPLDEPMDPDAASIAdKL---A----A---HPPQRL--LASPLQRSVLTAQALARATR 69  Ralstonia solan...
WP_011371746   3 LTLVRHCEVDKRYKNCynGHNDIGLSKNGEFQAKELAqKI---D----S---LEFDAV--FCSDLRRAKES---LKHSLH 67  Sulfurimonas de...
WP_004193433   3 VVLIRHPAVALGTGVCy-GASDVPLAAGAAAGAAGIRrRL---R----SlgvARASRV--WSSPLARCADVARALAGGVR 72  pseudomallei group
WP_011352900   3 VVLIRHPAVGVEPGICy-GRSDVPLAASADTGAQAVRaHLsalC----A---PLPEQV--WTSPLTRCVSVAERLAHACD 72  Burkholderia lata
3HJG_A        73 LP-M-TTEDDLQEMDFGDFDGMPFDLLTEHWKKLDAFWQSPAHHSLPNAESLSTFSQRVSRAWSQIIND-INDNLLIVTH 149 Vibrio parahaem...
WP_002075847  69 SK-L-EYSDLLMELNFGSWEGKPWSEIPKK--EYSYWAKDFVNFKVPNGESYQGLYERVSKFLDKILHSfSDEKIGIVTH 144 Leptospira inte...
WP_014224326  70 L-----RDDRLKEIHMGDWEMQRFDAITD--PRMQEWYDDYLHVATTNGESYQELFGRVASFLDEVRRL-PFERIAVFTH 141 Tannerella fors...
WP_005873573  69 ---A-IQDGRLMEINFGLWEMQRYDHIDD--PRLQDYYADYLRTPATGGESFVMQLERVSNFLEEVTAM-PFGHIAIFTH 141 Porphyromonas g...
WP_010993040  69 ---A-IRDARLKELNFGEWEMQEFDKICD--PRLEEWYNDYFHVAATGGESFMMQLQRVSEFLNEVSGk-EYKRIAVFAH 141 Bacteroides fra...
WP_011467115  73 EA-I-SADDRLLEMNFGDWEGKSWAEIPVA--EVDAWAKDTAHYVVPNGESYRDVESRCANFLLELA---SDKTHVIVTH 145 Saccharophagus ...
WP_011002318  70 LP-MpELDARLVELDFGAWEGCPWDDIPRA--ELDRWARDVLHGNPHGGESAADLVKRVTDWAAAMALA-PVPCVWAVTH 145 Ralstonia solan...
WP_011371746  68 VKsA-IYSDKLREKSWGEHEGMSYDEIVLR--EKIAYISFLQWIKILDGEPYLDYIKRVKEFFLDYLPSlKKENILVITH 144 Sulfurimonas de...
WP_004193433  73 AP-L-EIDPRLREIDFGAWEMQSWDAIGRD--ALDRWSADLMHAREHGGESAAQFVARVRPAFATLAVAa--RTSWVLTH 146 pseudomallei group
WP_011352900  73 VP-L-RRDADWQEMDFGAWEMQRWDDIDRAALDAW--AADLMHACAHGGESVARFAA--RVARRADAVAqFDGPQWAVTH 146 Burkholderia lata
3HJG_A       150 GGVIRIILAHVLGVDwrNPQWYStLAIGNASVTHI 184 Vibrio parahaemolyticus
WP_002075847 145 AGVIRTALCKLLNIP--LERGFY-FDLNYGSINKI 176 Leptospira interrogans
WP_014224326 142 GGVLMSARIYAEALP--PEEALR-NLTPYGGIVRI 173 Tannerella forsythia
WP_005873573 142 GGTILCAQVYAGLYE--LETCFE-HQTPYGGIVML 173 Porphyromonas gingivalis
WP_010993040 142 GGVLICAQIYAGILR--MEDAFD-ALTPYGGVVRL 173 Bacteroides fragilis
WP_011467115 146 AGVIKACIKLIKKQS--LKQVLK-MHIGFGEIISL 177 Saccharophagus degradans
WP_011002318 146 AGCMRALAAHWLQRP--VTETMQ-WPLQWGSACgf 177 Ralstonia solanacearum
WP_011371746 145 AGVIRVLLSIIHNIS--LEEAFS-IKVEYNSITLL 176 Sulfurimonas denitrificans
WP_004193433 147 AGVIRALASHALDAP--LDAMLA-RPIAMGGIVWL 178 pseudomallei group
WP_011352900 147 AGVIRAFASHVLRVP--LDTVLS-RPVPTGGVVWL 178 Burkholderia lata
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