Conserved Protein Domain Family
DUF92

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pfam01940: DUF92 
Integral membrane protein DUF92
Members of this family have several predicted transmembrane helices. One member of the family has been characterized as protein PGR (AtPGR). PGR is suggested to be a potential glucose-responsive regulator in carbohydrate metabolism in plants. This entry also includes protein VTE6, which is a Pphytyl-phosphate kinase catalysing the conversion of phytyl-monophosphate to phytyl-diphosphate.
Statistics
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PSSM-Id: 460391
Aligned: 284 rows
Threshold Bit Score: 116.825
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KDE04711            30 AFAVLLGFHGYRSASLNRSGATAACILGY-ITLANpLKL-FGVALLVFYFAGSRATK--VKALHKL--SLEDRHtpepta 103
agres:mru_0460      13 VLLFILGAISYKRKSLDMLGALIMIFMGI-TIIFS-AGVsWFILIVLFFILSIMATR--FSKPYKKeiGQYE-------- 80 
NZAGRC:Abm4_0222    13 VLLFIMGSFIYQRKALDFLGSLVMIIMGI-VILLS-AGLrWLLIIVIFFLMSIAATY--YSKDYKKrlGEFE-------- 80 
WP_020448449         1 ---MVLSALSLYFGLLTKSGSIASFFIGLaIGVLGaPS--WLILLILFALLGFIVTK--FRMSLKQelGVQEGK------ 67  Candidatu...
EQB69471            15 IVLVILFFLSQIFKLFDVKGAIGAVIIGA-IVSFA-GNLnWLILLILFAFFSHLATK--YKFEEKMklKQQEGT------ 84 
EQB67065            13 IFLIILFVASQIFHIFDLKGGLVALVLGI-IVDFA-GYFtWLILLLIFALVSFAATR--YRFAEKKmiKMQEGE------ 82 
Q6L2D7              13 IILIALFIVSRIFNVFDLKGSISALFVGY-VIAIA-GSLyWLILMIVFAMTSYIATR--FKIKEKTrnGLQEGK------ 82  Picrophil...
Q9HKS6               9 LILAILFVLSLKLRVLDLKGSVAALFIGA-IVSFI-GSIyWLILMLIFVASSFLATK--AFFSKKVkmKVQEGE------ 78  Thermopla...
licsiro:TALC_01161  12 AIVVALCIFSYKVNLMTAGACVVSFFMAT-AIGAAaGIW-WTLAFFTFPAIAFASTKigFKKKSEE--GLQEGK------ 81 
EQB64781            10 VVIPFLFVLGLRIKAFSREGAIAAGVIGS-LIIIG-GGWlYFVMLFLFLGLSYISTLagFEKKRSW--SLQEGI------ 79 
KDE04711           104 sastpkrlfkaGGNRDAFQVACNALFG--AL-CAITWrilyggevlefsqdrratwnaakvgerwcvvdervpsSRALVL 180
agres:mru_0460      81 ------------KTRTAKNVISNGLVA--F----LMAafgs--------------------------------yylpLAG 110
NZAGRC:Abm4_0222    81 ------------GRRTAKNVISNGVVA--F----VMAafgg--------------------------------yylpFVG 110
WP_020448449        68 -----------KGERTYRNVIANSLVPllVAiCAFAFgg---------------------------------eyYNLMAV 103 Candidatu...
EQB69471            85 -----------RGERKISNVAYGGAIG--VM-IALSNlfipf--------------------------------nfpfFI 118
EQB67065            83 -----------KGERKIKNVFYAGIIG--GA-IAAFHladpf--------------------------------llryFE 116
Q6L2D7              83 -----------NGERKTSNVMYAAMIG--LI-IALFNvsklg--------------------------------sfnyFE 116 Picrophil...
Q9HKS6              79 -----------HGERRISNVTYAALVG--IM-ITLIYgiyph-------------------------------mhnyFFE 113 Thermopla...
licsiro:TALC_01161  82 -----------RGERSTLNILGVGTIP--TV-IALAYfftdg-------------------------------agfeqTV 116
EQB64781            80 -----------KGERGARNVVAAGALP--AA-ISLLSfws--------------------------------isPKLVFF 113
KDE04711           181 AAIAFWACCAGDTLASELG-ILSStPPRLITSLRSVPRGTNGAISLWGLFVSLLGGILIG----FA--------AAISLa 247
agres:mru_0460     111 GFIGAVATATADTLASEIGvLQ---EPRLITSFKKVPAGTDGAISILGTSAAIVGAGIIG----IAs-------FLLGIm 176
NZAGRC:Abm4_0222   111 GFIGAIATATSDTLGSEIGiLS---EPRLITTFKKVPAGTDGAVSVRGTVAGIIGAAIIG----ISa-------FLLGVl 176
WP_020448449       104 AYIASISVAAADTVASEVGsLSP--KVYMITTGKKVKAGIDGGISVEGTIACIIGGIAAAylgcSLifselwgtEFIIL- 180 Candidatu...
EQB69471           119 MFAAAFAAITSDTFGSEIGvLD-D-RTYLITTFRRCETGINGGISIIGTFAAFLGSFLIA----LSy-------VILTRs 185
EQB67065           117 LFAISFAVVTADTFGSEIGvLD-P-NVIMITTLKRTQRGINGGISVLGEIAALFGALIIG----LCy-------ILLKIg 183
Q6L2D7             117 LFAISFATVNSDTFASELGvFD-K-NVFLITNFKRVRPGTNGGISLLGESSALFGSFIIG----LTy-------SLLMYr 183 Picrophil...
Q9HKS6             114 LFAISFAVINSDTFASEIGvID-Q-RVYMITTFKRVRPGVNGGVSLTGELAAILGGFIIA----MFy-------SIFAYh 180 Thermopla...
licsiro:TALC_01161 117 AFVSALAVSCSDTVASEIGvRDK--RVYMITTLKPCEVGLNGGISRFGMFVSAASALLFSfvafSLvmqd---------- 184
EQB64781           114 LYLVALGTILSDTAASEIGsLDE--NTYMILTLKPAETGINGGISILGTVVSFVFPIFFSilgyIIygvltsipL----- 186
KDE04711           248 wenpecsglkvtrivlgggKvvlslpwwgwIVGL--GAWGGL---VGSLIDSLLGATLQPSyysltrkkivhsptnpkdp 322
agres:mru_0460     177 p----------------dpLi---------AIKI--SVISGT---VGCFIDSILGAVLERR------------------- 207
NZAGRC:Abm4_0222   177 p----------------diWi---------ALKI--SIISGT---VGCFMDSLLGAVFERR------------------- 207
WP_020448449       181 ----------------------------------------GIigiIGCMIDSLIGATLERR------------------- 201 Candidatu...
EQB69471           186 l----------------nwEe---------PFFL--ILVAGF---LGSNIDSLLGAIFENK------------------- 216
EQB67065           184 d----------------vsMi---------ALLI--ITLFGF---LGCQIDSVLGALLENK------------------- 214
Q6L2D7             184 a----------------ffVy---------PVLV--ITLLGF---LGCQVDSILGSLLENR------------------- 214 Picrophil...
Q9HKS6             181 g----------------fnVp---------RIAE--VTAAGF---VGCQIDSILGALFENR------------------- 211 Thermopla...
licsiro:TALC_01161 185 ---------------------------ldvRFLI--PAFAGI---MGNIFDSLFGALFENK------------------- 213
EQB64781           187 ------------------------------IYLLdlTFLSGIlafAGCLFDSVLGETLENR------------------- 217
KDE04711           323 qeeiirvsgsgfAILSNNQVNLISSALTG 351
agres:mru_0460     208 ------------NFINNEHVNLLATISGA 224
NZAGRC:Abm4_0222   208 ------------RYLNNEHVNLLATITGC 224
WP_020448449       202 ------------GIVGKLGTNVISMACGA 218 Candidatus Methanomassiliicoccus intestinalis
EQB69471           217 ------------NKMSKGQVNLVASIVAV 233
EQB67065           215 ------------GKLSKGQVNFLSILFTV 231
Q6L2D7             215 ------------GRMSKGQVNLTATLISV 231 Picrophilus torridus
Q9HKS6             212 ------------GKLNKGQVNFLSSFLTV 228 Thermoplasma acidophilum
licsiro:TALC_01161 214 ------------GRMSKYTVNCSTSLIGA 230
EQB64781           218 ------------GYLTKYSVNFLSALFAT 234
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