4HTT


Conserved Protein Domain Family
tatC

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TIGR00945: tatC 
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Twin arginine targeting (Tat) protein translocase TatC
This model represents the TatC translocase component of the Sec-independent protein translocation system. This system is responsible for translocation of folded proteins, often with bound cofactors across the periplasmic membrane. A related model (TIGR01912) represents the archaeal clade of this family. TatC is often found in a gene cluster with the two other components of the system, TatA/E (TIGR01411) and TatB (TIGR01410). A model also exists for the Twin-arginine signal sequence (TIGR01409). [Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 273355
Aligned: 17 rows
Threshold Bit Score: 163.544
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4HTT_A         5 LTEHLRELRYRLIISIIAFLIGSGIAFYFAKY-------VFEILKEPILKSy----------pEVELITLSPTEPLFILI 67 
O05523        11 LLEHIAELRKRLLIVALAFVVFFIAGFFLAKP-------IIVYLQETDEAK------------QLTLNAFNLTDPLYVFM 71  Bacillus subtil...
BAA75388       8 LMDHIAELRRRILIIVVFFVIALVVGFFLATP-------MITYLQGAPTAQ------------DLPMNAFKLTDPLRVYM 68  Bacillus halodu...
P27857         9 LITHLIELRKRLLNCIIAVIVIFLCLVYFAND-------IYHLVSAPLIKQlp---------qGSTMIATDVASPFFTPI 72  Escherichia coli
AAA92109       3 LVAHLTELRSRLLRSVAAVLLIFAALFYFAQD-------IYALVSAPLRAYlp---------eGATMIATGVASPFLAPF 66  Azotobacter chr...
P44560        10 LITHLVELRNRLLRCVICVVLVFVALVYFSND-------IYHFVAAPLTAVmp---------kGATMIATNIQTPFFTPI 73  Haemophilus inf...
Q9ZM59         5 lkpHLQELRKRLMVSVGTILVAFLGCFHFWKN-------IFEFVKNSYKGT---------------LIQLSPIEGVMVAV 62  Helicobacter py...
Q10702        27 LVDHLTELRTRLLISLAAILVTTIFGFVWYSHsifgldsLGEWLRHPYCALpqsaradisadgECRLLATAPFDQFMLRL 106 Mycobacterium t...
P51264        29 ITEHLEELRQRTVFVFIFFLLAATISFTQIKI-------IVEIFQAPAI--------------GIKFLQLAPGEYFFSSI 87  Porphyra purpurea
WP_010879009  12 LREHIEELRKRLLRVCIILIVAVSISYYVSYPy------LLAFWYSLVG--------------ENPIYVFSPIEWVVIRL 71  Archaeoglobus f...
4HTT_A        68 KISLAVGFIIASPVILYQFWRFIEPALYSHEKRAFIPLLLGSILLFMLGALFAYFIVLPLALKFLLGLGFTQLlaTPYLS 147
O05523        72 QFAFIIGIVLTSPVILYQLWAFVSPGLYEKERKVTLSYIPVSILLFLAGLSFSYYILFPFVVDFMKRISQDLN--VNQVI 149 Bacillus subtil...
BAA75388      69 TFAFTSAFILVFPIILYQLWAFVSPGLHENERKATLAYIPIAFFLFLGGLSFAYFILFPFLIQFIGGLAERLH--INELY 146 Bacillus halodu...
P27857        73 KLTFMVSLILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGV--QVSTd 150 Escherichia coli
AAA92109      67 KLTLMISLFLAMPVVLHQVWGFIAPGLYQHEKRIAMPLMASSVLLFYAGMAFAYFVVFPIMFGFFASVTPEGV--AMMTd 144 Azotobacter chr...
P44560        74 KLTAIVAIFISVPYLLYQIWAFIAPALYQHEKRMIYPLLFSSTILFYCGVAFAYYIVFPLVFSFFTQTAPEGV--TIATd 151 Haemophilus inf...
Q9ZM59        63 KISFSAAIVISMPIIFWQLWLFIAPGLYKNEKKVILPFVFFGSGMFLMGAAFSYYVVFPFIIEYLATFGSDVF--AANIS 140 Helicobacter py...
Q10702       107 KVGMAAGIVLACPVWFYQLWAFITPGLYQRERRFAVAFVIPAAVLFVAGAVLAYLVLS-KALGFLLTVGSDVQ--VTALS 183 Mycobacterium t...
P51264        88 KIAIYCGIVATTPFGVYQVILYILPGLTNKERKVILPILIGSIVLFIVGGIFAYFVLAPAALNFLISYGADIV--EPLWS 165 Porphyra purpurea
WP_010879009  72 GFSLITSLIFLYPYVIYELYLFAKPGLYEHERRFLKAILIPSYGIFLFGTFFAYKFVVPTIYSIALTSAAD-----PYLS 146 Archaeoglobus f...
4HTT_A       148 -VDMYISFVLKLVVAFGIAFEMPIVLYVLQKAgvITPEQLASFRKYFIVIAFVIGAIIAP--DVSTQVLMAIPLLLLY 222
O05523       150 gINEYFHFLLQLTIPFGLLFQMPVILMFLTRLgiVTPMFLAKIRKYAYFTLLVIAALITPp-ELLSHMMVTVPLLILY 226 Bacillus subtilis...
BAA75388     147 gINEYFTFLFQITMPFGVLFQLPVVVMFLTRLgiVTPEFLRSVRKYAFFVLLVVAGFITPp-ELISHLMVTVPLLLLY 223 Bacillus halodurans
P27857       151 -IASYLSFVMALFMAFGVSFEVPVAIVLLCWMgiTSPEDLRKKRPYVLVGAFVVGMLLTPp-DVFSQTLLAIPMYCLF 226 Escherichia coli
AAA92109     145 -IGQYLDFVLTLFFAFGVAFEVPVATFLLIWVgiVDVASLRNSRPYVIVGCFVVGMVLTPp-DVFSQTLLAVPMWLLF 220 Azotobacter chroo...
P44560       152 -ISSYLDFALALFLAFGVCFEVPIAIILLCWTgiTTVKALSEKRPYIIVAAFFIGMLLTPp-DVFSQTLLAIPMCLLF 227 Haemophilus influ...
Q9ZM59       141 -ASSYVSFFTRLILGFGVAFELPVLAYFLAKVglITDASLKAYFKYAIVVIFIVAAIITPp-DVVSQIFMALPLVGLY 216 Helicobacter pylo...
Q10702       184 -GDRYFGFLLNLLVVFGVSFEFPLLIVMLNLAglLTYERLKSWRRGLIFAMFVFAAIFTPgsDPFSMTALGAALTVLL 260 Mycobacterium tub...
P51264       166 -FEQYFDFILLLLFSTGLAFEIPIIQLLLGISgtVSASQMLLAWRYIIIISTIIGAVLTPstDPVTQIIMSSAVLALY 242 Porphyra purpurea
WP_010879009 147 -AEKTLTNAFKLLISFGFFFQIPLFMVLSDRFgvVKYSTYRSLRIPVYILILVFITNLTMdfTGLTQIASLALFIIMY 223 Archaeoglobus ful...
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