Conserved Protein Domain Family
his_ut_repres

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TIGR02018: his_ut_repres 
histidine utilization repressor, proteobacterial
This model represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators. [Energy metabolism, Amino acids and amines, Regulatory functions, DNA interactions]
Statistics
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PSSM-Id: 188194
Aligned: 12 rows
Threshold Bit Score: 345.457
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P12380        12 PFYEKVKQAISEKIHSGVWRPHDRIPSEAELVAQFGFSRMTINRALRELTDEGLLVRLQGVGTFV--AEPKGQSA--LFE 87  Enterobacter ae...
P22773        19 PLYARVKQMIIQQIDNGSWPPHHRVPSESELVNELGFSRMTINRALRELTADGLLVRMQGVGTFV--AEPKGRSA--LFE 94  Pseudomonas putida
EIQ90202       7 PIYQRVKLAIIRQIRTGTWQPHQRVPSESELVTELGVSRMTINRALRELTNEGFLIRMQGVGTFV--AEAKAHSA--LLE 82  Yersinia pestis...
WP_010914586  10 PLYEKVKDYILANIGTGRWGKDRKLPSENELVASLGVSRMTVHRALRELTAAGFLIRLQGVGTFI--APPRPQST--LIE 85  Mesorhizobium loti
WP_000075034   3 PRYLQIKQFMLDNIESGRWPVGYRTPTELELTEQFGVSRMTVNKALRDLVSEGKLQRRPRLGTFVcaAEEKAESP--LLD 80  Vibrio cholerae
WP_011070506   4 PKFAEIKQYITGCIESGEWEENARVPSENQLAELFVCSRMTARRALTELTDNGVLERSQGLGTFV--AGRKSQSS--MLA 79  Shewanella onei...
WP_010970690  12 SLHQRIRNDVERHIMSGEWPPGYRIPFEHEMTRQYGCSRMTVNKALGELVQRGLIERRRRLGTFV--RQPHAQSA--VLE 87  Agrobacterium f...
WP_010918846   4 PLHQRIRADIEARIRSGEWPPGHRVPFETELMADYGCARMTVSKAMAALVDAGLIVRRKRAGTFV--ARPRVHAP--VLN 79  Caulobacter vib...
WP_010915524  14 SLHQRILSDISEKILSGAWAPGYRIPFEHELTTEYNCSRMTVNKALSQLAKAGLIERRRRSGSFV--RRPQSQAA--VLE 89  Mesorhizobium loti
AAM40877      11 tLHQRIRQDLEQRIHSGDWPPGHRVPPEHELMAQYGCSRMTVNKVLGLLADAGMIERRRRTGSFV--ARPHPHLEqvALS 88  Xanthomonas cam...
WP_011002558  10 PAFQRIKEDILSRIRSGEWQEGEMIPGETTLAQTFDVSRMTVNRALRELTADQILTRVQGSGTFV--AQQKYQAT--LVA 85  Ralstonia solan...
WP_006313419  19 PLYERVKEQIKEKIASGQWLTNHRIPSENEMVDMLGVSRMTANRALRELATEGVIVRVQGRGSFV--APKKRSAG--LMG 94  Agrobacterium s...
P12380        88 VRSIAAEIVARHHQHRCEVLLLEETRADHIQATALSVPEGTRIFHSLMVHYENEVPVQIEDRCVNAAVVPDYLHQDYTAT 167 Enterobacter ae...
P22773        95 VNNIADEIAARGHQHSCQVITLTEEAAGSERALALDMREGQRVFHSLIVHFENGVPVQIEDRYVNAAIAPDYLKQDFTRQ 174 Pseudomonas putida
EIQ90202      83 VHNIADEIAARGHRHSSQVLHLEARPASPEEAIALGIQPGQQLFYSQIVHYENDFPVQVENRCVNPSTAPDYMKQDFNQI 162 Yersinia pestis...
WP_010914586  86 INNIAAEIVERGNRHRSEVLVLETIMPTKELALSFEFPKRVAIYHSVVVNFENDLPVQLEERFVNPSLIPDYDKQDFSKT 165 Mesorhizobium loti
WP_000075034  81 IRNIADEILSRGKQYHNKVVEQRALSADEAVAIKLGVMVGSPVFYSEIIHYANDIPMQLEVRWVNSRSVPHYLDQDFTQI 160 Vibrio cholerae
WP_011070506  80 IRNIADEIKDRGHGYSVQQLALEQVNATAPIAIALALDVGSPVFHSILVHCEQGVPLQVEERYVNPAFAPDYLVQDFSEQ 159 Shewanella onei...
WP_010970690  88 IHDIEREVQAIGLVYGYRLDKRRLRPAGKEDGAAMALAADAPVLELTCTHFAGGVPFCLEERIVNIAAVPEAEGTDFSQV 167 Agrobacterium f...
WP_010918846  80 IPDIQSEIVARGETYAFRLLSRTLRQPDRDSPEEVALAAGGKLLALDGVHDADGRPFALERRLVSLKAVPEIAEADFAQT 159 Caulobacter vib...
WP_010915524  90 LHDIRIEVEALGLAYRYERLEQLKRRSNAEDRALLGLSAAGSVLWIEGLHFAGERPFALEQRLINLSAVPEAGDEEFLEI 169 Mesorhizobium loti
AAM40877      89 IPDIEVEMTTRGHVYQFQLLSRRVRAVRQRVPQERALGSRGKLLALESVHLADGSPFALEQRVIDITTVPEALAQPFDTI 168 Xanthomonas cam...
WP_011002558  86 IRNIAEEVAARGHRHRAELHKLERVRATEGMAAPFGVPAGRTLFHSLIVHFENDAPIQVEDRWVSAELAPDYMEQDFTQT 165 Ralstonia solan...
WP_006313419  95 VRNIADEIKERGSTHRPSLILAQTEVCGPDLATALEIGVGTKVFHSIIVHHEDDVPIQLEDRFVNAEIAPDYLMQDFTTL 174 Agrobacterium s...
P12380       168 TPHDYLSLIAPLTEGEHIVEAVQATAEECALLHIHAHDPCLLIRRRTWSTTHIVSHARLLFPGSRYRLQGRFGS 241 Enterobacter aerogenes
P22773       175 TPYAYLSQVAPLTEGEHVVEAILAEPEECRLLQIERGEPCLLIRRRTWSGRQPVTAARLIHPGSRHRLEGRFSK 248 Pseudomonas putida
EIQ90202     163 TPYSYLTQAAPLTEGEHIVEAVMPSPIERQLLELSEHEPCLLIRRRTWYGKAIVTAAQLLYPGPRYQLYGRFTP 236 Yersinia pestis PY-02
WP_010914586 166 ATYDYLMQKTPVTEVEHIISAIPADAETARHLNIDVGSCCLFLHRRTWTGAIVATISKLTYAGSRYSLGSRYSP 239 Mesorhizobium loti
WP_000075034 161 TPNQYLSQNCPLSAIEHTVEAIVADAHVKQALALAANEPCLLLNRRTWSGDKLVSSALLYHPGSRYKLSSKILF 234 Vibrio cholerae
WP_011070506 160 TPHEYLSQVAPLTEAHHTIEAIIASSELQQRLAIPATEPCLQISRRTWSRQGVVSFAKLVHPGSRFKLGGHLTF 233 Shewanella oneidensis
WP_010970690 168 GPGTWLLKMVPWSAAEHRISAVSADRKNAVALGIASGAACLVIDRRTWHGADYITRVRVTYPGDRHALVAQFSP 241 Agrobacterium fabrum
WP_010918846 160 PPGAWLLEHVAWTEAESRISAVNADPDDARLLALDEGAACLVVDRRTWREGQHVTRVRQIFPGEAYDLVARFGP 233 Caulobacter vibrioides
WP_010915524 170 AAGPWLIGRVPWSEAEHRIRAMAADEAIADALDIDPGAPCLVVERRTWSAEHPVTHVRFIYPAESHTLVARFTP 243 Mesorhizobium loti
AAM40877     169 APGSWLLRNVPWTRAEHRISAISADPAQARCLQVADGAACLVIDRHTWRGDQPVTYVRQLFLGGSYDLIARFAP 242 Xanthomonas campestri...
WP_011002558 166 TPNAYLMRAAPLQGVEYRIEARLPPREIAEMLRMDVREPCLMLRRKTLSQGQVASVATMWHPGERYQFTGSF-- 237 Ralstonia solanacearum
WP_006313419 175 TPNAYLTAAAPISRTEQFIEAASPQPWECKLMAISRNEPCLLVRRRTWSSSRAVTSVRLLYPGSRYRLESQE-- 246 Agrobacterium sp. ATC...
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