Conserved Protein Domain Family
hemH

?
PRK00035: hemH 
ferrochelatase; Reviewed
Statistics
?
PSSM-Id: 234585
Aligned: 447 rows
Threshold Bit Score: 230.451
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
68537091    9 AIAPDSGLLLLSFGGPEKAEDVVPFLENVTRGRGIPRARLEKVGEHYFALGGRSPINDQNKQLIRNIEAELarr------ 82 
48478020    1 ----MRRLILLSYGSPESIDELGEYLSMVFYGNPVPERIYNENRKKYELYNGRSPSNDILKCIEEKLKKALre------- 69 
226355379   6 VSPDTVGVLFMAYGGPETLDDMPGYLADIRAGRVTPSAVLEEITNNYRQIGGRSPLPEFTRAQVDATMQALeat------ 79 
16081447    1 ---MKSALLLLSYGSPERIEDLDEYLKNIFNGKPVPESVREENLRKYEMFGGRSPSNRIIESIARKLHEKIg-------- 69 
297567365   1 -----MNVLFMAYGTPYQRSETLPYYTDIRRGRPPTQELLEELEERYRRIG-RSPLNEITYAQAVRLEAALnatlplfpe 74 
291295789   4 IPGEPMNVLLMAYGTPYRQEEIEPYYTDIRRGRPPSPELLAELAERYHLIG-RSPLSEITYAQAVRLEAALnatlplypq 82 
15806151    5 TNQKPLGVLFMAYGGPENLGEMPGYLADIRAGRVTSQAILDEITNNYRLIGGKSPLPEFTRAQVEATMEQLast------ 78 
46198539    1 -----MNVLLMAYGTPYAPEEVEPYYTDIRRGRRPSEELLKELAERYEAIG-KSPLNEITLAQAVRLQALLnleappypk 74 
28493700   26 GASQYDAVVLLSFGGPEGPEDVVPFLKKVTSGRGVPDERLYEVAEHYNHFSGISPINDCNRRLRGALEKELfsr------ 99 
13542124    1 ---MKTAVLLLSYGSPEKMSDIDEYLSKIFGGKPVPKGVAEENYRKYEMFGGLSPSNRIIQSIRDRLQKRFdq------- 70 
68537091   83 -----------diDLPVYFGNRNWEPYVEDALQQMARDGIRHVYVFATSAWGGYSGCSQYQEDLRRAIAACEEagleAPK 151
48478020   70 ------------yDFDVTQAYKHWKPGIENIVEDS--KDFDEIFAIPLFPFSTNNVKNSYEKPFNEALKKYNV----TAR 131
226355379  80 -----------grPLKAYIGMRHWTPWIEDTVRQMLDDGIQKAVAIVLAPHFSSMSVAKYQKKIKAGLEMHHG----HID 144
16081447   70 ------------dDMDVILAYKHWNPSIEEAVKGL--GSYDNIVAIPLFSFYSQNVKDSYLNPLESALRRYGF----SPR 131
297567365  75 pl-aaspgprvqgPARVYLGTKHWHPFIAEAVKAMAQDGVKQAVGIVAAPHFSGRSIAEYQEKVTQALAELGD----PFE 149
291295789  83 pf-qsspgprvrgPARVYLGTKHWHPFIAEAVQAMAQDGVKQAVGIVAAPHFSSRSIAEYREKVEKALAELGH----PFR 157
15806151   79 -----------grPLKAYIGMRHWSPWIEDAVREMLDDGIEQAIAIVLAPQYSSLSVAKYQKKIKAALEMNHG----HID 143
46198539   75 rllgpfppraphgPARVYVGTKHWHPSIGEAVAAMHEDGVRRAVAIVAAPHYSLRSVAEYREKVDSALKTLPE----PID 150
28493700  100 -----------giRIPVLWANRNWQPQLEEVLREAYDRGFRAFLTLFTSAYSCYSSCRQYREDIAHAVERAGLs--gRII 166
13542124   71 -----------sgDVDVFTAFKHWYPSIGEVVPDL--KGYDNIVSIPLFSFFSENVKASYYKPLAEALEKNDI----RTK 133
68537091  152 VERLPQFHRHPTFIAEFARAVDaareQLR--------A--EHGEevaaqA----DLVFTAHSVPTVADKAAGPhkfg--- 214
48478020  132 VRFLNGLEDQELLYSAWIEKISghm---------------------yneS----PFLFAAHSLPLY--SDEST------- 177
226355379 145 FEFVNQYHTEPGYITALAQRVR----EGI--------Q--SFPEseqsdV----HVVLSAHSLPVRITREGDP------- 199
16081447  132 LEFVNGLANSDLFLPMWANIIS----EDAse-----------------dS----FYLFDAHSLPAP--DREED------- 177
297567365 150 IRFVEEYYDHPGYIRAVATRVV----EQLwrlv------------epqkA----LFLFTAHSIPERAA-QDGR------- 201
291295789 158 FRLVEAYPDHPGYIQALAHRVL----EQVwrlr------------epgrA----LFLFTAHSIPEKSAQDGV-------- 209
15806151  144 FAYIDNYHTEPGYITALADRVR----IGIqef--------------pedErddvHVILSAHSLPVRIIKEGDP------- 198
46198539  151 FVWVESYEAHPGLIAAYARRLE----EVI--------W--RLKNpg--kA----AYVFTAHSIPLSAVEKGDP------- 203
28493700  167 VDKLRQFFDHPGFVLPFIEGIQ----DCLeqvkergfK--VSRT----------AILFSTHSIPELDAAFSGPedahfgk 230
13542124  134 MEFVNGISNYDLFIPMWIHLIE---------------EkeKGDS----------FYLFDAHSLPHP--ENEED------- 179
68537091  215 gnlYSQQVLDASRLIQQAssfantpgsgadygwtgqlarhenvggrgdgpahtgetvgvdvgAGt----DLDVELVWQSR 290
48478020  178 ---YENLIINTARRLSNTf-------------------------------------------------lKDDYFYGFYSQ 205
226355379 200 ---YADQLLESARLVAQQ--------------------------------------------AGl---nEEQWSWSFQSA 229
16081447  178 ---YLFWLRYSTYKISQI--------------------------------------------LG-----LSRSDFGFQG- 204
297567365 202 ---YPGQIRATAALVAQTl-------------------------------------------------gLLHWDTAWQSA 229
291295789 210 ---YQAQVRTTAERVAQK--------------------------------------------LG-----LAHWDTAWQSA 237
15806151  199 ---YADQLHETARLVAAQ--------------------------------------------AGl---tDEQWSWSYQSA 228
46198539  204 ---YPRQVEKTAELIAKK--------------------------------------------LA-----LPRFHVAYQSA 231
28493700  231 ygaYVSQHKAVVEVIMSR--------------------------------------------LRvtdpdLQNYQLVYQSR 266
13542124  180 ---YLFWLRYSTYKITQI--------------------------------------------MG-----LRSSDFGFQG- 206
68537091  291 SGSPhvPWLEPDVCDHIEARAEaGNTRAIVLCPVGFITDHMEVKWDLDTEARDAAAKAGIPFVRVATPGLTAGFAGMVVD 370
48478020  206 GEHG--KWLYPSIYDYIDKLKE---YNSVTVIPIGFIYEHLEILYDLDIEFKNKLKDYGISYDRVETPSCSDTLVMAIRN 280
226355379 230 -GRSpePWLGPQLDEHLQALAE-KGVKKVVSVPVGFVSDHVEILFDIDIAAQEVARELGMTLVRPPALNTDPLFIGTLAS 307
16081447  205 -GHL--GWLGPSIYDVLNRIDA----SKITVIPISFLYDHLEILYDLDYEFRKAVEAKGMHYRRVRMPNDSAMMVNMIER 277
297567365 230 -GRTpePWIGPDINQKLEEAQA-AGYREVVVTAVGFPSDHLEVYYDLDYEAQNTAQKLGIRLLRTRSLNADADYIEVLRD 307
291295789 238 -GRTpePWIGPDVNERLEEAAA-QGYQEVVVTAVGFPSDHLEVFYDLDYEAQNTAARLGLRLLRTRSLNADPDYIEVLRD 315
15806151  229 -GRSpePWLGPQLDEHLRDLNE-QGIKKVVSIAIGFVSDHVEILFDIDIAAQEVAHELGMTLVRPPALNTDPLFIGTLAS 306
46198539  232 -GRTpePWLGPDINELLRTLKE-EGYEEVAVQAVGFPADHLEVFYDLDLEAQATARELGLRLLRARSLNADLDYIQVLKD 309
28493700  267 SGDPstPWLEPDINDAIRVLRG---CEAVLIVPLGFISDHMEVLWDLDNESMQTARECGLFAIRTPTPGTHPLYISGMVD 343
13542124  207 -GHE--GWLGPSIYNVYRKAKE----KKIIAVPISFLYDHLEILYDLDYEFRKKIEEDGYSYERVPMPNDSAIFITLLER 279
68537091  371 LVVGsDA 377
48478020  281 KIIS-NI 286
226355379 308 VIER-KV 313
16081447  278 AARS-AI 283
297567365 308 IVAR-KW 313
291295789 316 LVVR-EW 321
15806151  307 VIER-KA 312
46198539  310 LVEA-AW 315
28493700  344 LIVE-RL 349
13542124  280 IVSS-SI 285
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap