3FSX


Conserved Protein Domain Family
DapD_actino

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TIGR03535: DapD_actino 
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2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
This enzyme is part of the diaminopimelate pathway of lysine biosynthesis. This model represents a clade of the enzyme specific to Actinobacteria. Alternate name: tetrahydrodipicolinate N-succinyltransferase.
Statistics
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PSSM-Id: 274635
Aligned: 12 rows
Threshold Bit Score: 481.165
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3FSX_A         7 TGAAGIGLATLAAD---GSVLDTWFPAPELTE-SG----TSATSRLAVSd----vP--VELAA----LIGRDDDRRTETI 68  Mycobacterium t...
WP_010934713   2 TSALATGLATITAD---GTVLDAWFPAPELTA-VD----TTGTTVLDGDd----iP--EHLRL----LVGEDADRGVRRQ 63  Corynebacterium...
WP_003787244   4 RSAWGLGLATVTDD---GNTLDVWYPRPVLGD-EP----EDGHADL---------L--ASLSA----MERRDEARGVHTT 60  Actinomyces vis...
WP_011211278   4 QGATAVGIANVTTD---GTVLDTWYPSPELGT-FT----ETGTERLTEA------P--EGYAA----LLGVDEARGVEVV 63  Nocardia farcinica
WP_003863790   2 TTASATGIATLTST---GDVLDVWYPEIGSTD-Q------------------------SALTP----LEGVDEDRNVTRK 49  Corynebacterium...
WP_007052463   5 RTAWGWGLASVDAA---GTTLDVWYPELNLGE-A-----PAESDRPNHN------F--GTLAH------DEADARGIRRV 61  Bifidobacterium
WP_011185792  19 RTAWGYGLATVAGN---GAVLDTWFPEPQLGG-I-----PAGREKWIV-------P--AELEA----LAAPDPRRNVTVD 76  Leifsonia xyli
WP_023865408   5 agaagvglatLAAD---GSILDTWFPAPELTG-PG----TSGTSRLALSd----vP--PELTA----LIGRDDDRGTETV 66  Mycobacterium a...
WP_007400934  24 RRAWGWGLATVHED---GGVLDTWYPEPQLGC-PD----DSSA------------P--ADLHRv--tEAGRDAIRNVHTE 79  Propionibacterium
WP_003957035  10 tGAVAAGLATLTAD---GTVLDTWFPAPELAEaPG----PAGTERLTAEq----aG--ELLGAgavkALGPDARRGVEVV 76  Streptomyces cl...
WP_011692645  21 RSAYGYGVATVSTRngeATVLDVWFPAPSLGT-AA----DSLRNVESAD------PvlAEIAA-----AGTDADRGTEQQ 84  Arthrobacter sp...
WP_011273856   2 TSAYGNGFATLTDS---GDVLDTWFFEFDLGS-ADtgtaEAGTQVLDLTdasasaP--DSFRPfa-kLAGADDVRGTRRV 74  Corynebacterium...
3FSX_A        69 AVRTVIGSLDDVAADPYDAYLRLHLLSHRLVAPHGLNAGGLFGVLTNVVWTNHGPCAIDGFEAVRARLR-R-R--G-P-- 141 Mycobacterium t...
WP_010934713  64 AITTTIADLDAAPIDAYDAYLRLHLLSHRLVKPHGQNLDGIFGLLTNVVWTNHGPCEVKNFDITRAKLQ-A-R--G-P-- 136 Corynebacterium...
WP_003787244  61 VVRT-WADLDDAPQTVAGAYLRLHTLSHRLVKPNTVNLDGIFSRLPNVVWTSAGPCRAEDFETTRMRLR-A-AvgR-P-- 134 Actinomyces vis...
WP_011211278  64 AVRTTIADLSAAPVDAHDVYLRLHLLSHRLVKPHEVSLEGQFGLLANVVWTNHGPAAVDGFEQTRLKLR-A-R--G-P-- 136 Nocardia farcinica
WP_003863790  50 IVTTTI-DTDAAPTDTYDAWLRLHLLSHRVFRPHTINLDGIFGLLNNVVWTNFGPCAVDGFALTRARLS-R-R--G-Q-- 121 Corynebacterium...
WP_007052463  62 PVFV-VSQLDEPISNAADAYLKLHLMSMRMAKPNTLNLDGIFAQLANVVWTNYGPFAVEDFTLRKADVE-R-A--S-Tea 135 Bifidobacterium
WP_011185792  77 IVTVEI-DLDAAPASTPDAYLRLHILSHLLARPNTVNLEGVFGHLPIVAWTDGGPVLPDDLDRLRPALQ-R-D--G---- 147 Leifsonia xyli
WP_023865408  67 AVRTVIGSLNDVAADAYDAYLRLHLLSHRLVAPHGLNAGGLFGVLTNVVWTNRGPCAIEGFEAVRARLR-R-H--G-P-- 139 Mycobacterium a...
WP_007400934  80 VVHTVI-DLDAAPVDVSDAYLRLHLLSSRLAIPRTINLDGIFGVLPNNAWTTIGPIRMADLEKARMEARiA-H--A-P-- 152 Propionibacterium
WP_003957035  77 AVRTVISSLDDKPLDAHDAYLRLHLLSHRLVKPHGQSLDGLFGLLTNVAWTSLGPVAVDDIETVRLNAR-A-E--GlH-- 150 Streptomyces cl...
WP_011692645  85 VVFVQV-HLDEAPADTADAYLRLHLLSHRLVRPNTINLDGIFGKLPNVVWTNFGPAAVEGFELTRAKLR-K-R--G-A-- 156 Arthrobacter sp...
WP_011273856  75 AVTTKIADLDTPPADAYDAYLRLHLISGRKIKPHGCNLDGLFGLLSNVVWTNHGPCAVPGFESVRARLQ-AeR--G-P-- 148 Corynebacterium...
3FSX_A       142 ------------------VTVYGVDKFPRMVDYVVPTGVRIADADRVRLGAHLAPGTTVMHEGFVNYNAGTLGASMVEGR 203 Mycobacterium t...
WP_010934713 137 ------------------VTVYLVDKFPRMVDYVLPSGVRIGDADRVRLGAHLAEGTTVMHEGFVNFNAGTLGNSMVEGR 198 Corynebacterium...
WP_003787244 135 ------------------VQVHSVDKFPRMTDYVLPSGVRIGNGANVRLGAYLSEGTTVMHSGFVNYNAGTLGRSMVEGR 196 Actinomyces vis...
WP_011211278 137 ------------------VTVYSVDKFPRMVDYVVPAGVRIGDADRVRLGAHLAAGTTVMHEGFVNFNAGTLGASMVEGR 198 Nocardia farcinica
WP_003863790 122 ------------------VTVYSVDKFPRMVDYVVPSGVRIGDADRVRLGAYLADGTTVMHEGFVNFNAGTLGASMVEGR 183 Corynebacterium...
WP_007052463 136 alafasqaglpaaapaatVNVFGVDKFPRMIDYVVPTGVRLGDADRVRLGAYLSSGTTVMHAGFVNFNAGTLGVSMVEGR 215 Bifidobacterium
WP_011185792 148 ------------------LHVTAIDKFPRLLDYVTPDRVRIADASRVRLGAHLAPGTTVMHEGFVNFNAGTLGASMVEGR 209 Leifsonia xyli
WP_023865408 140 ------------------VTVYGVDKFPRMVDYVLPTGVRIADADRVRLGAHLAPGTTVMHEGFVNYNAGTLGASMVEGR 201 Mycobacterium a...
WP_007400934 153 ------------------FTVLLIDKFPRMVDFVVPTGVRIGDADRVRLGAHLAVGTTVMHEGFVNFNAGTLGHSMVEGR 214 Propionibacterium
WP_003957035 151 ------------------LQVTSIDKFPRMTDYVAPKGVRIGDADRVRLGAHLAEGTTVMHEGFVNFNAGTLGTSMVEGR 212 Streptomyces cl...
WP_011692645 157 ------------------VTVYGVDKFPRMVDYVVPAGVRIADADRVRLGAYLAEGTTVMHEGFVNFNAGTLGTSMVEGR 218 Arthrobacter sp...
WP_011273856 149 ------------------VTVYSVDKFPRMVDYVVPTGVRIGDADRVRLGAHLAEGTTVMHEGFINFNAGTLGSSMVEGR 210 Corynebacterium...
3FSX_A       204 ISAGVVVGDGSDVGGGASIMGTLSGGGTHVISIGKRCLLGANSGLGISLGDDCVVEAGLYVTAGTR-VT-M--------- 272 Mycobacterium t...
WP_010934713 199 ISAGVVVDDGSDVGGGASIMGTLSGGGKQVISLGKRCLLGANSGCGIPLGDDCVIEAGLYVTAGSK-II-Vrgavaeatg 276 Corynebacterium...
WP_003787244 197 ISQGVVIGDGSDVGGGASTMGMLSGGGRQRVALGKRCLLGANSGLGIPLGDDCVVEAGLYLTAGTK-VSlMpqgg--vvp 273 Actinomyces vis...
WP_011211278 199 ISAGVVVGDGSDIGGGASTMGTLSGGGTTVISIGERSLLGANSGLGIPLGNDCVVEAGLYLTAGTK-VT-T--------- 267 Nocardia farcinica
WP_003863790 184 ISAGVTVDDGTDVGGGASIMGTLSGGGQHVISLGKRCLLGANSGCGIPLGDDCIIEAGLYITAGTK-VL-F--------- 252 Corynebacterium...
WP_007052463 216 VSQGVVVGDGSDIGGGASIMGTLSGGGKLRNSIGEHSLLGANAGIGISLGDNCTVEAGLYITAGTK-IT-Iwdkak-aaa 292 Bifidobacterium
WP_011185792 210 VSQGVVVGDGSDIGGGASIMGTLSGGGVQRVSIGERALLGANSGIGISIGDDTVVEAGLYVTAGTKvVV-Vdgpv--das 286 Leifsonia xyli
WP_023865408 202 ISAGVVVGDGSDIGGGASIMGTLSGGGTEVISIGKRCLLGANAGLGISLGDDCVVEAGLYVTAGTK-VI-T--------- 270 Mycobacterium a...
WP_007400934 215 ISQGVIVGDGTDIGGGASIMGTLSGGGKERVTIGRGCLLGAEAGIGISLGDNCVVEAGLYVTAGTK-VT-L--------- 283 Propionibacterium
WP_003957035 213 ISAGVVVGDGSDIGGGASTMGTLSGGGNVIISIGERCLIGAEAGVGIPLGDECVVEAGLYVTAGTR-VT-M--------- 281 Streptomyces cl...
WP_011692645 219 ISAGVVTGDGTDVGGGASIMGTLSGGGKEKISLGERVLLGANSGVGISIGDDSVVEAGLYVTAGTR-VR-Vigpk--dad 294 Arthrobacter sp...
WP_011273856 211 ISGGVVVGDGSDIGGGASVMGTLSGGGKEVISIGERCLLGANSGVGISLGDDVTVEAGLYITFGTK-VT-Ltdevakqlg 288 Corynebacterium...
3FSX_A       273 -P-----D-SNSVKARELSGSSNLLFRRNSVSGAVEVLARdgQGIALNEDLHAN 319 Mycobacterium tuberculosis H37Rv
WP_010934713 277 lN-----D-GDTTKALELAGANNILFRRNSISGAIEATAWksQAVELNDALHAN 324 Corynebacterium diphtheriae
WP_003787244 274 gNhglfkE-PRVVPARELAGASNVLFRRNSQSGAVEALARggKSIELGSTQHAG 326 Actinomyces viscosus
WP_011211278 268 -A-----D-GQVVKAADLSGRDNLLFRRNSTTGAVEVVHRkgTGIELNEDLHAH 314 Nocardia farcinica
WP_003863790 253 -------D-GSLHKASTLAGSNGLIFRRDSVSGQVVAVPNt-KVVELNTALHSN 297 Corynebacterium glutamicum
WP_007052463 293 gE-----P-LEVVKGAELSGKDNILFIRNSVNGRIEARYRk-VGIELNAKLHKN 339 Bifidobacterium
WP_011185792 287 gR-----P--QTVKAVELSGAHGLLFRRNSVTGAVEVLRRdgAGVRLNTALHA- 332 Leifsonia xyli
WP_023865408 271 -P-----E-GKQLKARELSGGNNLLFRRNSLTGAVEVVARggTGITLNEDLHAN 317 Mycobacterium avium
WP_007400934 284 -P-----N-GKVVKASELSGASDILYIRDSTTGIVKARGRgnHKIELNSDLHQN 330 Propionibacterium
WP_003957035 282 -P-----D-GEIVKARELSGASNILFRRNSVTGAVEARPNnaVWGGLNDVLHSH 328 Streptomyces clavuligerus
WP_011692645 295 gE-----DtTRVVKAVELSGVPNLLFRRNSASGAVEVLPRkgQTVELNEALHAN 343 Arthrobacter sp. FB24
WP_011273856 289 kQ-----E-GESVKASELSGASGILFRRNSISGAVEAVANa-SAIELNEALHAN 335 Corynebacterium jeikeium
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