Conserved Protein Domain Family
fadE

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PRK09463: fadE 
acyl-CoA dehydrogenase; Reviewed
Links
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Statistics
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PSSM-Id: 236528
Aligned: 236 rows
Threshold Bit Score: 1022.06
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
117926832  27 LSGPIMALMQ--GAMPPLSQTEREALESGTVWWERELFSGRPDWSKLQNLPA-DTLSKEEQAFLEGPVQRLCARLDEWRI 103
294507216  75 VSAGVMGLMEalQFLPTISETEQTAIDAGTVWMEGELFSGKPDFEKTLDQLY-PELSDDEQAFLDEPCEEVCAMVDDWQV 153
220908447  66 LTVPLMQAIQslKLLPPISETERAAIDAGTVWVEGEFFSGKPNWQRINQEPY-PQITPELQAFLDGPVEQVCRLASDWEI 144
294140089   1 --MSLRTQLK--KIMPSISTTEQEALDAGDVWLEGSIFQGKPDFSALRDIPV-AKLTADEQAFLDGPVTSLIEMIDDFAI 75 
268317260  76 VSGPLMAFMRasGFLPKISDTERTAIEAGTVWVEGELFAGKPNFDRLLRETNyPSLTDEERAFLEGPVEELCRMVDDWEV 155
158335306  68 LTSFVVKTLQnlKIFPKISETEKAAIEAGNVWVDGEFFAGKPNFERILNEPY-PQLTLDIQAFLDGPVEQVCRMASDWEI 146
77362285    1 --MSLRTKLK--KVLPSISITEQEALDAGDVWLEGSIYQGKPDFSALRAVPA-AVLSADEKAFIDGPLQDLLGMIDDTEI 75 
42523637   78 VTSGLLAFMKkmQFLPKISDTEKAALDAGAVWVEKDLFSGNPNFGNLLKEDY-PQLTAEEQAFMDGPVNNLCKVLDHWKI 156
83815152   55 VSAGVMGLMEalQFLPTISETEQTAIDAGTVWMEGELFSGKPDFEKTLDQLY-PELSDDEQAFLDGPCEEVCAMVDDWQV 133
170725861   1 --MSIRTRLK--KVLPTISTTEQEALDAGDVWLEGSIYQGVPDFNALKNIPV-AKLSVDEQAFLDGPVATLLEMVDNFAI 75 
117926832 104 KQEEHDLPADLWEMLKQEGFFGMIIPREYGGLGFSARGHSAVITKIASRSVTAAVTVMVPNSLGPAELLMRYGTPEQQRY 183
294507216 154 -HQRGDLSTETWDYLKEKGFFGLIIPEAYGGKGFSVAARSAVVQKLGGHSVPLSITVMVPNSLGPGELLLHYGTDEQQDH 232
220908447 145 -YRRQDLPVQVWDYLKQERFFGMMIPQGYGGLGFTNLAYSTVMAKLASRSFIHTATVGVTNSLGPAKLLLNYGTDAQKDY 223
294140089  76 QGD-KHIPDHILSYLKQNKFFSLIIPKSYGGLEFSPYANSTIVATIAGKSSAVAVTVMVPNSLGPGELLMHYGTSDQRDY 154
268317260 156 -WRRRDLPPEVWQFIREKGFLGIIIPKEYGGLGFSSLANSAVVQKLSSRCGPLATTVMVPNSLGPAELLIHYGTQEQRDY 234
158335306 147 -YQRQDLPPDVWTYLKQERFFGMMIPEEYGGLGFSNLAYSAVMAKLASRSFTHVATVGVTNSLGPAKLLLRYGTKEQRHH 225
77362285   76 QNGI-HLPDYILDFLKKERFFSLIIPKSFGGLEFSPYANSTIVATIATKSSAVAVTVMVPNSLGPGELLLHFGTQEQQAH 154
42523637  157 -HKDKDIPKEAWDIIKKEKFLGMIIPKEYGGLGFSALAHSEVIMKISSRSLSTAITVMVPNSLGPAELLAHYGTDAQKNR 235
83815152  134 -HQRGDLSAETWDYLKEKGFFGLIIPEAYGGKGFSVAARSAVVQKLGGHSVPLSITVMVPNSLGPGELLLHYGTDEQQDH 212
170725861  76 -QGAKHIPDDVLTFLKTNKFFSLIIPKAYGGLEFSPYANSTIVATIAAKSSAVAVTVMVPNSLGPGELLMHYGTDEQRDF 154
117926832 184 YLPRLANGREIPCFALTSPRAGSDAGAIPDTGVVCRGNFRGETVVGIRLNWDKRYITLAPVATLLGLAFRLYDPDNIMGN 263
294507216 233 YLPRLARGEILPSFALTEPNAGSDAGAMESTGEVFEDE---DGELKLRLNWEKRYISLAAISGVLGLAFKLHDPENHLGK 309
220908447 224 YLPRLAQGEEIPCFALTEPTAGSDAASITAQGVVFRGA---DNQLYLRLDFRKRYITLGTIATLIGLAFKLSDPDNLLGK 300
294140089 155 WLPRLAKGLEIPCFALTSPEAGSDAGGIPDVGIVTMGEFEGKQVLGLSITWDKRYITLAPIATVLGLAFKVQDPKGLLGG 234
268317260 235 YLPRLARGEEIPAFALTEPGAGSDAGAIQASGVVFRGE---DGKLYIRLNFQKRYITLAAIATVLGLAFKLRDPDNLLGK 311
158335306 226 YLPRLARGEEIPCFALTEPKAGSDAASITSSGVVFKGE---DDQLYLKLNWNKRYITLGAIATILGLAFQLHDPNNLLGK 302
77362285  155 YLPRLANGTDIPCFALTSPEAGSDAGGIPDLGTVTKGMYNGEEVLGLEITWDKRYITLAPIATVLGLAFKVVDPDGLLGG 234
42523637  236 YLPRLATGDEIPCFGLTEPTAGSDAGSITSTGVLFKGP---DGKLQIKLNWNKRWITLAAISTTIGLAFRLRDPENLLGK 312
83815152  213 YLPQLASGEILPSFALTEPNAGSDAGAMESTGEVFEDE---DGELKLRLNWEKRYISLAAISGVLGLAFKLHDPENHLGK 289
170725861 155 WLPRLANGLEIPCFALTSPEAGSDAGGIPDIGTVTFGEYEGNQVLGLSVTWDKRYITLAPIASVLGLAFKVQDPKGLLGG 234
117926832 264 IRDLGITLALIPTQTAGVSIGTRHDPLGVPFLTGPTRGHQVFIPM-SYLIGGEQGIGQGWRMLMACLSEGRGISLPALSV 342
294507216 310 GEDLGITCALVPTDTPGVKLGRRHDPLGVAFFNCPTEGEDVVLPL-DAIIGGRDGAGEGWAMLMDALSAGRGIMLPAQAV 388
220908447 301 GENPGITCALLPASTPGITISTRHDPMGVPFFNSPIAGQDVVISV-DQIIGGVEQAGQGWKMLMQTLAAGRGISFPASCT 379
294140089 235 KENLGITCALIPKSHPGVQLGNRHDPMGVNFYNGTTRGENIFIPM-DFIIGGQANIGRGWSMLVACLGAGRGISLPALGA 313
268317260 312 GEDLGITCALIPTNTPGVKLGMRHDPLGVPFYNCPVEGHDVVVPI-DAIIGGPEWAGKGWRMLMESLAAGRGISLPASSA 390
158335306 303 GEHPGITCALIPTETSGVIHNRRHDPMGVPFYNSPLEGHDVIVPI-GQIIGGIEQAGQGWKMIMQTLAAGRGISFPATCT 381
77362285  235 KENLGITCALIPKEHPGVELGNRHDPMNIRFYNGTTRGNKVFVPM-DFIIGGQKNIGRGWQMLVSCLGAGRGISLPALGV 313
42523637  313 GEDVGITCALIPSSTPGVVLGRRHDPLGIPFYNCPTQGKDVIVNAeDAIIGGVAGAGKGWLMLMECLAAGRGISLPAQAT 392
83815152  290 GEDLGITCALVPTDTPGVKLGRRHDPLGVAFFNCPTEGEDVVLPL-DAIIGGRDGAGEGWAMLMDALSAGRGIMLPAQAV 368
170725861 235 DEDLGITCALIPKAHPGVQLGNRHDPMGVNFYNGTTRGEDVFIPM-EFIIGGQKNIGRGWAMLVACLGAGRGISLPALGA 313
117926832 343 GAAKLAARSSGNYSRVRKQFGLAIGRFEGVQEALGRIGLNAYRMESARTLTVTILDQGERPSVAAGIVKYHLTEGMRQTI 422
294507216 389 GGGKMVTRVAGGHAAVREQFGLSIGKFEGIEEPLARIAGYTYIMDAARTYTNGAVDQGEKPGVVSAIMKYNTTELQRDLV 468
220908447 380 GVAKLVARVTGAYARVRQQFGLSIGRFEGIEEPLARIGGLTYLLDAARIYTCGAVDGGERPPVVSAIAKYHFTEIARKLV 459
294140089 314 AVSQCSFKSSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQESMRVLTTEGLGIGLKPSVVTAIAKYHMTELGRDIL 393
268317260 391 GGLKLIYRVASAHARVRRQFGLPIGMFEGIEEPLARIGGFNYLVEAGRVYTCGGLDRGAKPAVVSAIMKYNTTELGRQAI 470
158335306 382 GVTKLVARVAGAHAVVRKQFGLSIGRFEGVEEPLARIGGFTYMIDAARLYTCGAVDQGEQPAVVSAIAKSQTTELARRVV 461
77362285  314 STAQVAFKSASEYAAVREQFGLAIGQFEGIQEKLADIAGKTYLQEAMRVLTTEGLGMGLKPSVVTAIAKYHMTELGRDVL 393
42523637  393 GGAKLAARVVSAHSLVRRQFGMSIGRFEGVEEPLARIGAAAYQLEAMRRYCLGAIDKGIKPGVITAMQKYYATEMGRQVI 472
83815152  369 GGGKMVTRVAGGHAAIREQFGLSIGKFEGIEEPLARIAGYTYIMDAARTYTNGAVDQGEKPGVVSAIMKYNTTELQRDLV 448
170725861 314 SVSQCSFKSSAEYAAVREQFGLSIGKFEGIQEKLADIAGKTYLQESMRVLTTEGLGIGLKPSVVTAIAKYHMTELGRDIL 393
117926832 423 NDAMDIWGGTAICRGPHNLLAHAYQAIPIGITVEGANILTRTMMIFGQGAIRAHPYLLQEMEAVTGQQpvaerVIAFDRL 502
294507216 469 NDGMDVLAGNGISQGPSNLMGLSYQAQPISITVEGANILTRTMMIFGQGAIRCHPYALDEIEALMEGD-----VDAFDDA 543
220908447 460 NDGMDILGGAGICRGPRNLLANIYTAMPIPITVEGSNILTRTMMIFGQGVIRCHPYLYREVTALQNRE-----AIGFDQT 534
294140089 394 NSAMDIQAGKAIQRGPQNTLASAYFAQPIAITVEGANILTRNLMIFGQGVMRCHPHMQSMVEAIHSDHkn--aDKVFNSI 471
268317260 471 NDGMDILGGNGISRGPRNLLAHGYIAAPIGITVEGANILTRTLMIFGQGAIRCHPYAFKEISALERGD-----VQAFDDA 545
158335306 462 LDGMDILGGAGICRGPRNLLANIYTAMPIAITVEGANILTRSLMIFGQGAIRSHPYIYDEILALEQSD-----VAAFDQA 536
77362285  394 DSAMDIQAGKAIQNGPQNTLASGYVAQPIAITVEGANILTRNLMIFGQGVMRCHPYLQSMVESIHSEDkn--aDKEFNRI 471
42523637  473 NDSMDIMGGAGISMGPRNVLAEIYIATPIGITVEGANILTRTLMIFGQGALRAHPFAYAEVKTAEAGD-----LKGFDRA 547
83815152  449 NDGMDVLAGNGISQGPNNLMGLAYQAQPISITVEGANILTRTMMIFGQGAIRCHPYALDEIEALMEGD-----VDAFDDA 523
170725861 394 NSAMDIQAGKAIQRGPQNTLASGYVAQPIAITVEGANILTRNLMIFGQGVMRCHPYLQSMVEAIHSDDtn--aDKVFNSI 471
117926832 503 LWAHVGYTMMNGLRALVYGLLGNAGAAApqgVCATERKCYQRISHWSAAFAFMSDLALARLGGSLKRRESLSALLGDALS 582
294507216 544 FWSHIGHVVRNGFRALGLSLTRGRLASSp--VRGSAAPYYRKMAWASASFAFFADLAMGSLGGMLKRKEKITGRFADILS 621
220908447 535 FWQHLGFLVRNSCRALLLGLTRGRIAYSp--VRGPTARYYQKLTWASTTFALLTDLVLLGYGGSLKRQEKLTGRLADMVS 612
294140089 472 FRKTLGYSVNNSLRAFRLGLLPFTASSSs--KLPEVATYEKAVNKLASKLAVYADFSLLVLGGKLKQAEMLSARLGDVMS 549
268317260 546 FWKHVGLVVRNGARALLLSLSRGRLARTg--VSGPAARYARKLAWASASFAFLADLAMAALGGNLKRKEKLTGRFADIFS 623
158335306 537 FWSHLGLIVRNGVRAGLLCLTRGRLTRSp--VQGETAMYYRKLAWAAATFANFSDLAMLSLGGSLKRREKLTGRFADMLA 614
77362285  472 LRKTVSYSVANSLRAFRLGVLPFTAGASs--TLPEVREYEKAAHKLSAKLAVYADFSLLVLGGKLKQAEMLSARLGDVMS 549
42523637  548 FWGHIGHVIRNTCRAVLLSCSRGFLASTp-dVHPQMKVYVRRLTWTSATFALLSDVAMGVLGGQLKAKQKITGRFADILA 626
83815152  524 FWSHIGHVVRNGFRALGLSLTRGRLASSp--VRGPAAPYYRKMAWASASFAFFADLAMGSLGGMLKRKEKITGRFADILS 601
170725861 472 FAKTVGYSVNNSLRAFRLGLLPFTAQATs--TLPEVIPYEKSVNKLASKLAVYADFSLLVLGGKLKQAEMLSARLGDVMS 549
117926832 583 HLYMASAILHRYSKD---GSPPQDRPIMEAALEDSLLQVRQALVEVVRNFPDPVVALLMRLVVFPTGLAQR---RLPQHH 656
294507216 622 WMYLGTAVLTRFEKE---GRPEEQEAFLHWSMQHAFAQMQEAFDGLFENLKVPGGTWLLRGLVAPWSRLNTigeRPGDDL 698
220908447 613 WMYLGTASLRRFTAE---GSQPADLPFVHWSLQYSLAQIQLALEGILGNLP---LPAIARHLLLGYGRLNPigaLPQDSL 686
294140089 550 YLYAAMASIRYYEQKlpsEQRAQAAPYFHYATRWSLCKAEEALLAFLENFPSSATRKLMRVLTVTFSAKMP---KVNDNL 626
268317260 624 WMYLATATMRRFEAE---GRREEDRPFFDWAMQYAFHRMQQAFDGLFDNLRIPGLTWFLRGPAAWWSRLNRlsaPPSDRL 700
158335306 615 WMYLGSATLRRFEAE---GQQVKDLPLVHWPMQYAFSQIQKAVEGVIYNLP--ILSAGLRHPILGLWRLSPlgtEPSDEL 689
77362285  550 FLYAAMASIKYYEQKvssSEREQAAPYFHYATRFALQSAEEALHKFLDNFPASGTRKFMRFITMNYSTKMP---KISDDL 626
42523637  627 NMYMATAILRRFEYE---GRREEDLAFAHYNLKRCMANIQTGFDGIFDNLKIPGLRWFFKGWIGAWSRINSvgsQASDGW 703
83815152  602 WMYLGTAVLTRFEKE---GRPEEQEAFLHWSMQHAFAQMQEAFDGLFENLKVPGGTWLLRGLVAPWSRLNTigeRPGDDL 678
170725861 550 YLYAAMASIRYYEQKlpkEQREQAAPYFHYATRWSLCKAEEALLAFLENFPSSATRKLMRLLTVTYSAKMP---KVNDDL 626
117926832 657 LHRVAILMQQSGPARERLTAGIYLGGGDEGDsMAELEAAFIATERSDEAEKRLIQWMKSRrwdpiLSNGMHVpEGYLQSA 736
294507216 699 GGTLARAIQEKGGAREWLTEDLYVPDDPDQP-LGELERAFRLSREAYHVGQKIKAAIRAG-----DLPKRRP-HQLLEEA 771
220908447 687 GHEIAQALQTPGNERDRLTGGIYLPDHPDEA-LGRLEEALQLVTQANDIFNRIKAASRTG-----QLPHLPV-EQLIDTA 759
294140089 627 VRELAEQAQ--LNTEFKKNLTHLIKPVVGDG-NYINEQAYLAKLDCLELLAKVKKGLKSRe----FKSGIRF-PITLDNA 698
268317260 701 GHRVAQLMLTPGEQRERMTAGMYVPSDPNEA-LGRLERAFRLAYQEDELLRKIYAAVKRG-----ELPRARP-EQLVRQA 773
158335306 690 GHQVSQILLMPGPERDRLTRDIYLPNHTEEA-VGRLEEALRLSVQTASILKTIKNAIARG-----QLPPSKP-SQLVDKA 762
77362285  627 IRELAKQAQ--LDTAFKAQITHLVKPVKGDG-HYINEQAYKAKMASLGELAKVKKALRAKt----IKAGIRF-SITLDNA 698
42523637  704 SHGIAAAMLKEGGIRERLSDGIYLPTDRNEA-IGRLEHAFSVTNKAEAAEKKVKKAIREG-----VLPKKKV-HLLLDEA 776
83815152  679 GSTLARAIQEKAGAREWLTEDLYVPDDPDQP-LGELERAFRLSREAYHVGQKIKAAIRAG-----DLPKRRP-HQLLEEA 751
170725861 627 VRELAEQAQ--LNTEFKRNLTHLIKPIPGDG-NDINEQAYLAKMDCLPLLAKVKKGLRSRq----FKAGTRF-SITLDAA 698
117926832 737 VQEGVISELEAKQLDDTLERRMRVVRVDEFPAVCWLGE------------------------------------------ 774
294507216 772 VEHGVITEEDRDLVRRADAARERYIQVDAFDLEEYRQGrmlpgqpadrgaldssiveglerdvtdvevtpedvdggaphp 851
220908447 760 LSAGLVSQPEVKLLRECELVRHDTIQVDAFVLKEYSHIsfprnskng--------------------------------- 806
294140089 699 LAAKVINATEHKQLQSYNLKRERAIRVDEFDFNMNLISekadlkian--------------------------------- 745
268317260 774 VEKGIITAEEASIIQEAEAARWDAIQVDAFTLEEYRRYynappsgiea-------------------------------- 821
158335306 763 LEEGIINTQEARSLQKAEISRSNTIQVDSFTLEEYQQRdaiavds----------------------------------- 807
77362285  699 LAANVITAAEHTQLIDYNTKREKAIRVDEFDFDMNLLDdnaqpv------------------------------------ 742
42523637  777 LQKNVITQDELKLIQESDAVRYDAILVDDFSQEEYMSR------------------------------------------ 814
83815152  752 VEHGVITEEDRALVRRADAARERYIQVDAFDLEEYRQGrmlpgqpadrgaldssiveglerdvtdvevtpedvdggaphp 831
170725861 699 LEAKVIELSEHKLLQDYNLKRERAIRVDEFDFDMNLITeka--------------------------------------- 739
117926832 775 ---------------------EVAA 778
294507216 852 rgdgapdatdedepeadrsgaREPA 876
220908447 807 ------------ektrdginyCPAN 819
294140089     -------------------------    
268317260 822 ------------agdgsreavATES 834
158335306 808 ---------------pifkqvVTGS 817
77362285  743 ----------------nplksVVNQ 751
42523637  815 -----------------------HS 816
83815152  832 rgdgapdatdedepeadrsgtREPA 856
170725861 740 -------------------elKIAN 745
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