1JSX,1XDZ


Conserved Protein Domain Family
GidB

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pfam02527: GidB 
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rRNA small subunit methyltransferase G
This is a family of bacterial glucose inhibited division proteins these are probably involved in the regulation of cell devision. GidB has been shown to be a methyltransferase G specific to the rRNA small subunit. Previously identified as a glucose-inhibited division protein B that appears to be present and in a single copy in all complete eubacterial genomes so far sequenced. GidB specifically methylates the N7 position of a guanosine in 16S rRNA.
Statistics
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PSSM-Id: 396880
Aligned: 15 rows
Threshold Bit Score: 153.975
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1JSX_A  20 QKNQLIAYVNMLHKWNKAYNLTSVR--DPNEMLVRHILDSIVVAPYLQGER------FIDVGTGPGLPGIPLSIVRPEAH 91  Escherichia coli
P53363  20 DLQKINLYIKRILLLNTRFNLISNSnsNFNSILNLHVIDSLLGLSTVKEINps---eVLDVGSGAGFPGIILAIFDSSRK 96  Borreliella burgdorfe...
Q55787  41 QIEAMVKLYQGVLVGNARLNLTRIT--APLDFLEKHLWDSLAGVLLSDHSRncpqarVIDIGTGGGFPGLPVALVWPQWS 118 Synechocystis sp. PCC...
O25703   1 MNPLLQDYARILLEWNQTHNLSGAK--NLSELEP-QITDALKPLEFIKDFKs-----CLDIGSGAGLPAIPLALEKPEVK 72  Helicobacter pylori 2...
O54571  21 RYADAVRYAELLAEAGVKRGLIGPR--EVPRLWERHLLNCAVLSEVVPEGVt-----VCDVGSGAGLPGIPLALVREDLK 93  Streptomyces coelicol...
Q50203  36 RLNIAQRYVDLLANTGIERGLLGPH--EANRLWDRHLLNSAVVAELLDPGDr-----VVDIGSGAGLPGLPLAIARPDLQ 108 Mycobacterium leprae TN
P9WGW9  15 rlglARRYAEALAGPGVERGLVGPR--EVGRLWDRHLLNCAVIGELLERGDr-----VVDIGSGAGLPGVPLAIARPDLQ 87  Mycobacterium tubercu...
O66106  26 LCALLKQYLEELILFNTRAHLVHVT--HTEELITHHLLDSLSAWPHFTNARa-----IADIGSGAGLPGIPLACALALYA 98  Treponema pallidum su...
1XDZ_A  22 QLEQFELYYDMLVEWNEKINLTSIT--EKKEVYLKHFYDSITAAFYVDFNQvn---tICDVGAGAGFPSLPIKICFPHLH 96  Bacillus subtilis
P75220   2 NNSKLKQYVQLVQTANQNFNLTGLK--TEGEIYEHLVQEIIELFNEYDSYFdh--kkVADLGSGNGCPGVILKLLFPQIK 77  Mycoplasma pneumoniae...
1JSX_A  92 ----FTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEEf----pSEPPFDGVISRAFASLNDMVSWCHH-LPGEQGRFY 162 Escherichia coli
P53363  97 ----YYLLERSKKKSTFLKMIKLELDLENVKILEYEIEK------EKKKYEFITIRAFRNMNEYALILKN-LLKGGGLIM 165 Borreliella burgdorfe...
Q55787 119 ----VALLDSTHKKINYLEELGHRLGLANLAYLVARAEAvgnqpqHRSQYDLALIRAVGEGVVCAEYALP-LVKVGGTVV 193 Synechocystis sp. PCC...
O25703  73 ----FILLEPRIKRAAFLNYLKSVLPLKNIEIIKKRLEDy----qNLLQVDLITSRAVASSSFLIEKSQR-FLKDKGYFL 143 Helicobacter pylori 2...
O54571  94 ----ITLLEPLLRRTNFLTEVVELLGLDHVTVVRGRAEEvm---gKLPPVHVVTARAVAPLDRLATWGIP-LLRPYGEML 165 Streptomyces coelicol...
Q50203 109 ----VVLLEPLLRRVTFLREVVAELGLD-VEVVRGRAEElwv-rdRIGERDVAVSRAVAALDKLTKWSIP-LLRPGGQIL 181 Mycobacterium leprae TN
P9WGW9  88 ----VVLLEPLLRRTEFLREMVTDLGVA-VEIVRGRAEEswv-qdQLGGSDAAVSRAVAALDKLTKWSMP-LIRPNGRML 160 Mycobacterium tubercu...
O66106  99 peteLTLIERREKRIAFLENACARLALPHLRIVHADAHDl-----TPYTYDAITFRALCPLNHPTVYMLLnKLRPGGVIL 173 Treponema pallidum su...
1XDZ_A  97 ----VTIVDSLNKRITFLEKLSEALQLENTTFCHDRAETfgqrkdVRESYDIVTARAVARLSVLSELCLP-LVKKNGLFV 171 Bacillus subtilis
P75220  78 t---LDLIDSKHKKVNFLKEVIQTLELNNTQALCARIEN------HTEQYDTLCSRGLGSIIEVNAFALK-LLKPNGIIF 147 Mycoplasma pneumoniae...
1JSX_A 163 ALKGQMPEDEIALLPEEYQVESVVKLQVPAL-Dg----ERHLV 200 Escherichia coli
P53363 166 AYKGKFDRINLEVNQIKNLFSKIEVKSLNSKlRv----DRNLV 204 Borreliella burgdorferi B31
Q55787 194 LYRGQWSAAEAEQLERACALLGGKVSATVAAvTpwsgaQRHFI 236 Synechocystis sp. PCC 6803 substr. Kazusa
O25703 144 FYKGEQLKDEIACKDTECFMHQKRVYFYKSK--------ESLC 178 Helicobacter pylori 26695
O54571 166 ALKGDTAEEELKAATAALSKLGAEQTSILHVgEgv--vSPLST 206 Streptomyces coelicolor A3(2)
Q50203 182 AIKGEHVFDEIHQHRRVMASLGAVDVMVVVCgAny--lCRPVT 222 Mycobacterium leprae TN
P9WGW9 161 AIKGERAHDEVREHRRVMIASGAVDVRVVTCgAnylrppatvv 203 Mycobacterium tuberculosis H37Rv
O66106 174 AYKGKRKLIEQETRDFLPQSCSVFPLHVPFLhEa-----RHLV 211 Treponema pallidum subsp. pallidum str. Nichols
1XDZ_A 172 ALKAASAEEELNAGKKAITTLGGELENIHSFkLpieesDRNIM 214 Bacillus subtilis
P75220 148 HIK--QSLDQYLEFEDSEQKDQFKPLFFKFFhGk----RQQIL 184 Mycoplasma pneumoniae M129
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