Conserved Protein Domain Family
dapto_LiaX
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NF038025: dapto_LiaX 
daptomycin-sensing surface protein LiaX
LiaX (lipid-II###interacting antibiotics X), as described in Enterococcus faecalis, is expressed under control of the the LiaR response regulator, and is involved in the process of resistance to daptomycin and to antimicrobial peptides of the innate immune response.
Links
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Statistics
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PSSM-Id: 468317
Aligned: 20 rows
Threshold Bit Score: 678.271
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_010769140   1 MKERERILDLVKKGVLSTEEALDLLESMATAKDEKHIEQAADKVSSTNkdltdkekhsseeendqvSDLIDALENGQEVE 80  Enterococcus ph...
WP_010754075   1 MNERERVLDLVKKGVLSTEEALDLLEGLAKEKGEKHIQKANEEVIAEKkd--------------avDRLLEDPEDKDFAQ 66  Enterococcus asini
WP_010759962   1 MNERQRVLELVKKGIISTEEGLDLLESMAKAKDEAQIEQDADKVDSYHrd--------------qaANLADEWENGQEER 66  Enterococcus pa...
WP_010740058   1 MNERQRIMELVKKGILSTEEGLDLLETMAKAKDEAQIKQAADKVDSYHrd--------------qaTNLVDEWEKGKDTE 66  Enterococcus ma...
WP_007208051   1 MNERERILDLVKKGVLSTEEALDLLESIAKEKDASQIKRAAEEVKANN----------------------NASDKIADKT 58  Enterococcus it...
WP_016185258   1 MNERKRILDLVKKGVLSTEEALDLLEGIAQDKDASQIEKAAEQVQAKK----------------------AEAQPTDES- 57  Enterococcus su...
WP_015077189   1 MKERERILELVKEGVISTEEALVLLENSAHKEGKAAVKKEQANIQKPIlkkapvapipeikeeksaEPVLSDIEDVAEEG 80  Carnobacterium ...
WP_007721537   1 MKQRERILELVKQGIISTEEALVLLENAAKKEGKEAIKKENAHTHVEEpqptppkd--tffediteDPAFSQLNEDSQN- 77  Carnobacterium ...
WP_010009008   1 MNERERILDLVKQGVISTEEALMLLENLAQDKNTAEQHSTTKTQTERQ-------------------------STETTT- 54  Loigolactobacil...
WP_014569364   1 MNERERILDLVKKGVISSEEALVLLENLAKQQGT-QAGSPADDTAPEA-------------------------HSEQTET 54  Lacticaseibacil...

WP_010769140  81 EPTPnFKDKENEDKENLEKILDDLATEANKTSVELDEVNAEIQGVRTEIKETQEQLMQLDTKEELGNLTEEELSSRSALQ 160 Enterococcus ph...
WP_010754075  67 d----IQDQEAEDKKTLDSLLDDLATEANRTSVELDEVNVELAGVASQLAEAQSKLMELNTKEELDILSDEELAERKELE 142 Enterococcus asini
WP_010759962  67 e----TK---EDGLEDLEAYFDELATEANQISTRIDEINREKQELKEDIREKQEVLMELNTKEELDALSEEDEAIRERVE 139 Enterococcus pa...
WP_010740058  67 e----ADRSEEQDLEELEAYFDDLATEANQISAHIDEINQKKKELKAALHEKEEVLMELDTKEELDTLSEEDDDIREAVE 142 Enterococcus ma...
WP_007208051  59 -----IEELEMEDKENLEAILESLTQKATQASAELDELSVELDGIAKEQAEVAEQLMQLNTKEELGELTADEQRQRQALE 133 Enterococcus it...
WP_016185258  58 ------EFIDEQESEDLEAILDELASQTTSISASLDQVQEQMNFVTKERQTIKDTLTEYYTHEELEEVSDEEIKVRERLE 131 Enterococcus su...
WP_015077189  81 EARL--EQEQNQDRERLEAILEELANEASGYSAKLDETNKVIDDLKEQINAKKEVQMVFETKEELDELSAEEEAEVNILE 158 Carnobacterium ...
WP_007721537  78 -EDF--SNEEQKDREQLEKILESLANEASSYSVKLDEKNLEIAMIKSKLRLVQEKLMVLETKEDLEGLNPEKLPEMNQMK 154 Carnobacterium ...
WP_010009008  55 --------AAEKETTDNTAALAELQDQIKEVD-------AQLKDAQHELKAQQEHLQVLDTMEDLETLSADKLAERDRTK 119 Loigolactobacil...
WP_014569364  55 DDQS--TQEQQEANKDTDAALTELNTEIAEAAGALDAATAQVTSIGKQIEANNEQIIVLDTMEDLEALSPEKYQKRGELK 132 Lacticaseibacil...

WP_010769140 161 EELTGLEDSLDGLLEEKLTLEAELKNIRKNQWSETKESIGSKFDipDDWKDQATDTINQVGE-------KMAEAGSQLGK 233 Enterococcus ph...
WP_010754075 143 AELKALELSQEDLEAEKENLESHLKGVKKDQWSQMKDDFRSKFN--DEWKDQASDALNQAGE-------KMAEAGSQIGK 213 Enterococcus asini
WP_010759962 140 AEIKVWEEQLIRLENQELEQQEALESIREDQ-EAKGKRIYMNFEipEDLKEQASETFNQVGE-------KLGEAGVQFGK 211 Enterococcus pa...
WP_010740058 143 EAIDNLKEKIAELEEEAEEKEEELKNVQDNQNETRKERNRARFDipDDLKDQASETFSQVGE-------KLGEAGVQLGR 215 Enterococcus ma...
WP_007208051 134 QESKDLTEAAEELKAEKEAVEDQVKSIRKQQWKQTKEKVSQKFDipDDWREQANEKLNQANEtlnqvsdKLLKNGSKLGK 213 Enterococcus it...
WP_016185258 132 DEVKQLDHQLTKLHQQKRELEEQMKEIRREQWIYSKEKMSQKFDipEDWKEQATEKLTNAs-------eKVVKHGTKFSK 204 Enterococcus su...
WP_015077189 159 NEIDALEDEVAILEDEKEELEEKLKTVKKQQWGTHKKNITEKFEipDDWKETATETLNTVGD-------KVTEAGTQFGK 231 Carnobacterium ...
WP_007721537 155 NEINELKAQLEDLEEDKSELENQLKTVKRKQWGTQKKQISEKFEipEDWKETMDETLNQVTG-------KVVDTGNQFGK 227 Carnobacterium ...
WP_010009008 120 ETIGKTESQIAVLNDEKTALQKQVAELHKAQRDHYKERLADKLNlgDDWKDTATDTLNQVGE-------KVGDAGSQLGK 192 Loigolactobacil...
WP_014569364 133 QENQKLNDQLAELKGQVETMKANLATLRRQKHDLERQKISDKIf-nDDWQKDARDVFSEFGK-------NIGDATSQLGG 204 Lacticaseibacil...

WP_010769140 234 FLKQTFQTVSESVNDNMEWKDVSLRVPGIATTKFDHEFYYEAPQASILDVKVANGNVQFKTWEKEDVKVEAKIRLYGKMD 313 Enterococcus ph...
WP_010754075 214 LLKQTFSTVSQTLNDNVEWKDINMRVPGVANTKFDHTFEFDASEATILDVKVANGNVEFDVWEEDHVKVDAKITLYGKMD 293 Enterococcus asini
WP_010759962 212 FMKKAIKTVSETVEENVDWKDINVKVPGVATTKFEHQFLYSDVEPTLIDVKLANGKVTFKSWDEKDIKVDAKVKLYGKMN 291 Enterococcus pa...
WP_010740058 216 LMKKTWKTVSDTVEENVDWKDFNVKVPGLVTSKFEHQFLYTDVEPTLIDIKLANGKVTLKAWDDAAIKVDAKIKLYGKMN 295 Enterococcus ma...
WP_007208051 214 TFIKTIQTLTDTIGENVEWKNIHVKVPGVAATKFEKTYEFPASEATLIDMKVANGKIEVKQSLDDTVKIEAAIKLYGKLT 293 Enterococcus it...
WP_016185258 205 VLLRTLQNVSDSISENVEWKDFHVKVPGVASTKFDKEFVFDATPATILDVKIANGAIVLKRWSEDFVKVDAKIKLYGKFH 284 Enterococcus su...
WP_015077189 232 FMKETFS----SVIENVDWKDVNIRVPGLATTKFDHDFVYPASEATILDVKVANGDVVFKNWDSEDIKIEAKIKIYGRLD 307 Carnobacterium ...
WP_007721537 228 FMKNTFS----TVIENMDWKDVNVRVPGLASTKFTHEFNYPESSASILDVKVANGNVLFKNWDSQDIKVEAEIKIYGKID 303 Carnobacterium ...
WP_010009008 193 FIKNTAQ----TIMENVDWKEVNIRVPGIATTKFDHDFVYENASATILDVKVANGDVNFKTWDSPDIKVSAHVKLFGKME 268 Loigolactobacil...
WP_014569364 205 FVKDTVN----NVLDNVDWKNVTVTVPGLATEKFEHVFKFPDSQATILDVKVANGDVKFKTWDQPGIQVEAAIKLYGKMD 280 Lacticaseibacil...

WP_010769140 314 AETPFAAFEQRSQIEVDDDRISFQIPNKRIRADLVFYLPARTYDHVSIKLLNGNITIEVLDAKDIYTKSTNGNILFNQVK 393 Enterococcus ph...
WP_010754075 294 GATPLDAFNARSRMEVDDDHILFHVPNKRVRADLTFYLPTQVYDHVALKLLNGNVVVKKLEAKDVYTQSTNGNMDFKEID 373 Enterococcus asini
WP_010759962 292 EATPLQSFMERSQIEVNDEHITFQVPNKRVNAELVFYLPKRTYDHVAVKLLNGNLMVEELDAKDVYAKSTNGNIVFKQIN 371 Enterococcus pa...
WP_010740058 296 EATPLQSLMERSQIEVNDEHISFQIPNKRVQAELVFYLPKRTYDHVAVKLLNGDLNVEEMDAKDVYAKSTNGNISFKQID 375 Enterococcus ma...
WP_007208051 294 GEDPEEVFANRSQVSVDEERISIQIPNKRIRADLVIYLPAKTYDHVSIKTLNGELDIKDLEAKDVYFKSTNGNINLQELS 373 Enterococcus it...
WP_016185258 285 SENAEELFAERSQIEVDNEAIRLHIPNKRVRADLVVFLPDQTYDHVAIKMLNGTIIVDELTAKDVYMKTTNGDIQLHHID 364 Enterococcus su...
WP_015077189 308 VENPFEAFLERSTIEVNDEHLLFHVPNKRIRSDLTFYLPERTYDHTAVKLLNGNLRFEEFEAKDIYAKSTNGNIVFDRLT 387 Carnobacterium ...
WP_007721537 304 TATPLEAFEKRSTVEVTDEKMLFHVPNKRLRCDLVFYLPERVYDHTAISLLNGNVKFEDFEGKDFYIKCTNGNVFFQNLT 383 Carnobacterium ...
WP_010009008 269 SDSPLENFLQRSELANTADTLTFKVPNKRIQADLTFYLPERTYDHTTIKLLNGNVTLEGFEGDDLFIKGTNGQLTFSSVN 348 Loigolactobacil...
WP_014569364 281 ADSPFEAFKDRSRIDVTDDHFSFQVPNKRVQADLVISLPKRTYDHVSVRLLNGSADLTGVNGKDFYVKSTNGQMNFTNVD 360 Lacticaseibacil...

WP_010769140 394 ATMLEIEGVNGNIDVRSSEVLDSIIETVNGNVTIEDAPQNLAVSLVNGDVRVTAKNLDLHKIEASSVNGNVKVALPLELG 473 Enterococcus ph...
WP_010754075 374 ATMLEINGVNGNITVASGDVRDTIIENVNGNITVKTTPQTIGASLVNGDIRLTFAGTNLKKVDASSVNGTVKAAFAPTLG 453 Enterococcus asini
WP_010759962 372 ATMLEIQGVNGNIEIREGEVLDSIIETVNGTISSRAAVQNYGISLINGDVKLTVGHDTLKKIKASSVNGNVKVSLPKALG 451 Enterococcus pa...
WP_010740058 376 ATMLEIQGVNGNIEIREGAILDSIIETVNGNITSKAAVQNYGISLVNGDVKLTAGHDSLQKIKASSVNGNVKVSLGKNIG 455 Enterococcus ma...
WP_007208051 374 ATMLEIEGVNGEMNVQSGTIRDMVIESVNGGISITTTPETAAISLVNGDIKCSFSKESLRQLKATSVNGNIKLAVPVTIG 453 Enterococcus it...
WP_016185258 365 ATMLELEGVNGSIGIEAGTIRDTVIENINGAIIVTTTPETALLSLVNGDIKLTFEQENLRKLQASSVNGDVKVALPVTLG 444 Enterococcus su...
WP_015077189 388 ATMLETEGVNGNVSVLDSQIRDLLISSINGGITARGDIKSGNLSTVNGTVKATLTGTDLKRLEASSVNGAVKVAIPSNLS 467 Carnobacterium ...
WP_007721537 384 ATMLETDGVNGTVTVLDSTVRDLMVKSVNGGIVTRGKIKSGNLSTVNGTVKVTLEGEDLTRLAASSVNGSVKVSFPKNYS 463 Carnobacterium ...
WP_010009008 349 ASMLEVEGINGNIKVSGGRLIDALVNTVNGEVRFVSNVESAELTTVNGDVKATITENTLTKLVASSVNGNVKVAVPTELA 428 Loigolactobacil...
WP_014569364 361 GVMIESEGVNGSIKVQGSHTHDLLLTTVNGDVSVDADPATAALKTVNGTVRATYHT-DFTKIEGTSMNGNVKVAVPASIA 439 Lacticaseibacil...

WP_010769140 474 VDGYAKTSLGRINSRMTEYEVVREKKERTNQMLQFRRVSDEAMAQVSLSTTTGSIYLKD 532 Enterococcus phoeniculicola
WP_010754075 454 LEGTAKTSLGKINSRMSDYEVIREKKAKMNQLLQFRRVAEDSWAQIELATTTGNVLIKD 512 Enterococcus asini
WP_010759962 452 LEGIAKTSLGSINHRLSDYEVVREKKEKTNRLLQFRRTNEQ-MAQIDVSTTTGSIFLKD 509 Enterococcus pallens
WP_010740058 456 LEGLAKTSLGSINDRLSNYEVIREKKEKTNRLLQFRRVADK-MAKIDVSTTTGSIFLKD 513 Enterococcus malodoratus
WP_007208051 454 LNGTAKTSMGSIQSRLTHYEVIREKKEKMNQLLDFERVNEE-MATIDLGTTTGTIYLKD 511 Enterococcus italicus
WP_016185258 445 LAGEAKTNIGAVQSRMTGYEIIREKREKMNQLLEFERVMDH-MAQIDVSTTTGSVYLKD 502 Enterococcus sulfureus
WP_015077189 468 VEGTSKTNLGSIQSRLENTEIIKEKKDRTNQFQEFRRVASENILVVKLSTTTGSIMLKD 526 Carnobacterium maltaromaticum
WP_007721537 464 VEGEAKSNLGTIQNRVENLETLKERKDRTSQLLEFRRIADTQSLILKLETTTGNILLKE 522 Carnobacterium sp. AT7
WP_010009008 429 ISGKSKTRFGAIKSRLSNVDVLNERHNTGNSVYDFERDLGDTPAKLELSTTSGNVLLKD 487 Loigolactobacillus coryniformis
WP_014569364 440 LKGEARTHFGSIKSRLSNVAEP----AKGLKRFELDRP-GTGNSELKLNTTSGNIQLKD 493 Lacticaseibacillus rhamnosus
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