7BB4,6RFZ,6RG1,6RGG,6RGJ,6RGR,6RGU,6T96,5C9O


Conserved Protein Domain Family
PLL_lectin
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cd22954: PLL_lectin 
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PLL-type lectin with a 7-bladed beta-propeller topology
This model characterizes a family of lectins with a seven-bladed beta-propeller topology, which may specifically bind to O-methylated sugars, a carbohydrate modification whose function is not entirely understood. The pattern of methylation may be associated with defense agains pathogens, and family members such as PLL2 and PHL could play a role in circumventing host immune system defenses. Family member PLL3 has also been shown to interact with O-methylated glycans, but has higher affinity to L-fucose and its derivatives.
Links
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Statistics
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PSSM-Id: 438567
Aligned: 156 rows
Threshold Bit Score: 160.999
Created: 13-Oct-2021
Updated: 13-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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  next features
Conserved site includes 12 residues -Click on image for an interactive view with Cn3D
Feature 1:putative carbohydrate binding site [chemical binding site]
Evidence:
  • Structure:7BB4: Photorhabdus laumondii lectin PLL binds glycerol, contacts at 4A
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1                  #                                    # # #                            
7BB4_A        23 ALSGIVSVANNa-----------------------------------DNRLEVFGVStd--------------------- 46  Photorhabdus la...
WP_082559084 253 TVSAWAAAVRGggrnt--------------------------vynpdTRTAEIFTLRtd--------------------- 285 Kitasatospora s...
WP_020553691 119 DLPDVATQISKwdlqp--------------------------gdilnSNPHVILFAGwnnkaagtfsyyqessrsrptny 172 Streptomycetaceae
WP_020516335 162 QAGSVGTARRTwstetaalytpirydrirenaapvvhsrpgvvyeddSTFTQAFGRGvn--------------------- 220 Actinoplanes gl...
ONI85264      85 GVSDESGGANTqglagsgist----------------riekdqlkpgDALIDAAGTSntr-------------------- 128 Actinosynnema s...
RKT09791     202 GKAELVAVASRswqggclgtpatetrt-----gaqssrvddlagwvqQVRANATARTa---------------------- 254 Streptomyces sp...
WP_086785852  95 AVATVIVETSLr----------------------------------nYDGGHSSSVGl---------------------- 118 Crossiella equi
WP_089907768  20 AQAPATAAEQSgdplillsc-------------------stystnksVTRSEVIARAqsw-------------------i 61  Lentzea albida
WP_082874453   8 GAPYLAAVENTspgerh------------------------agfskvQTYLERFGYLgpa-------------------t 44  Arthrobacter sp...
WP_148641176  24 TLTAVPAQAASsvd-------------------------------gtITRTEVMERA----------------------- 49  Streptomyces sp...

Feature 1             # # #                                                                      
7BB4_A        47 -sAVWHNWQTApl----------------pNSSWAGWNKFn--------------------------------------G 71  Photorhabdus la...
WP_082559084 286 -gAMIHAYNTN-------------------GEGWSGWHLId-------------------------------------pG 308 Kitasatospora s...
WP_020553691 173 esGSLNASTLA-------------------GHPTSTYSAYrynkia---------------------------ddapdpG 206 Streptomycetaceae
WP_020516335 221 -gDLINTYRLT-------------------NGSWSAWRTI---------------------------------------G 241 Actinoplanes gl...
ONI85264     129 hvVLFEKWADAart-------------kywGFEQSGTNPTvnrkhri--------------------------vkypyeG 169 Actinosynnema s...
RKT09791     255 -sAVYDPAKQTstvftvdnkgrvmgayninGQGWSTWTPIse-----------------------------------rpA 298 Streptomyces sp...
WP_086785852 119 -fQQLQSWGTReqrldpkwstnaflgamekTYPGGRWNKLp-------------------------------------vG 160 Crossiella equi
WP_089907768  62 daGVTYNQGGCytnr-----------ygdyRMDCSGMTSMawglsss--------------------------rttytlD 104 Lentzea albida
WP_082874453  45 prELGVLDDPTeg----------------aLRSFQEFFHLpv------------------------------------tG 72  Arthrobacter sp...
WP_148641176  50 --QAWLNQHVPydqgg---------yyggyREDCSGFVSMawhlsssentdsldsrslttriplsdlqpgdaldndphdG 118 Streptomyces sp...

Feature 1                                                                           #            
7BB4_A        72 VVt---------------------SKPAVHRNs-----DGRLEVFVRGT----------DNALWHNWQTAa--------- 106 Photorhabdus la...
WP_082559084 309 ARf--------------------vGGPAVVHNp----vNNTLEVFATGT----------NGFMYRATWSR---------- 344 Kitasatospora s...
WP_020553691 207 PAia-------------------tASRASAYNp----sTQTSEIFAVGA----------DGSMLHDSNTA---------- 243 Streptomycetaceae
WP_020516335 242 DWki-------------------aGDPVPVYEp----nTKSTEVFGRGN----------DGRLIHTWQAA---------- 278 Actinoplanes gl...
ONI85264     170 SNaheykpyrynkivddeqseeavSAPVQAVYeq---nTKTTEVFARGV----------DNRLIRVWNTN---------- 226 Actinosynnema s...
RKT09791     299 GTkp------------------fiGSPTALYNp----aTAAIELFAVDS----------DGLMWHTYYLAd--------- 337 Streptomyces sp...
WP_086785852 161 EVaqgv---------------qrsAHPTRYQPea---aDAQRIVDALGQpgetsvnvpaNRAVYEPSTATteffargerg 222 Crossiella equi
WP_089907768 105 QVshvi--------------prseLKPGDALNk----yDEHVAIFAGWA----------DAARTQPIVLN---------- 146 Lentzea albida
WP_082874453  73 VFddat--------------reamMRPRCGLPdv---rPGELAFATTCAw--------aDRTLTYAFDTGta-------- 119 Arthrobacter sp...
WP_148641176 119 NIl--------------------gSGHVILFDhwvdkaAHKFQYIAEGSr--------aTGTFSTADYLDggg------- 163 Streptomyces sp...

Feature 1               ###         #                                                            
7BB4_A       107 -------DTNt--------WSSWQPLYGGIt-----------------SNPEVCLNs--------dGRLEVFVRGsd-nA 145 Photorhabdus la...
WP_082559084 345 -------ATG---------WGPWTTTGDWKf----------------rGNPTTVYNpd-------tRTAEVFALRt--dG 383 Kitasatospora s...
WP_020553691 244 -------GAG---------WSGWTTLGPGAkf---------------kGAPVAAFNps-------tNAMELFALG----T 281 Streptomycetaceae
WP_020516335 279 -------GGA---------WSAWAGIGTWKi----------------sSDPVAVYEpn-------aGVTEVFARG----L 315 Actinoplanes gl...
ONI85264     227 -------GQG---------WSEWAAHGDWQm----------------kGHPAGVYQpn-------tDTTEVFARG----T 263 Actinosynnema s...
RKT09791     338 -------AQG---------WRAWTGTGTTKf----------------sGGASAVYNps-------tRTAEVFATTtd-gP 377 Streptomyces sp...
WP_086785852 223 emvhvwnTDGq--------WSPWETHQPGFhi---------------kGNPVSVYDta-------tQTTEVFARD----S 268 Crossiella equi
WP_089907768 147 -------HGGdpv---yahRTVWSAAFAARftpirydnivddvtvagnEAPAVVVEg--------nGAMQVFARDtntgK 208 Lentzea albida
WP_082874453 120 -----dvAGNaefdairqaIQTWQAVGGLTf-----------------TEVAVGSS----------PDIRIGWRPa---A 164 Arthrobacter sp...
WP_148641176 164 ----dgqIGGh-------pASGYFGLRYNNiaada--------pppapAPVAAAATagqsvynadtKTAEVFAIG----T 220 Streptomyces sp...

Feature 1                                                                                        
7BB4_A       146 LWHIWQTAa-HTNSWSNWKSLGGTLt--SNPAAHLNa-DGRIEVFARGADNALWHIWQTAahTDQWSNWQSLKSv--iTS 219 Photorhabdus la...
WP_082559084 384 VMAHLYNT--NGEGWSGWYALDPAArfaDEPTVVHNpvNNTLEVFATGTNAFMYRATWSR--ATGWGPWTTTGDwk-fRG 458 Kitasatospora s...
WP_020553691 282 DNAVWHAYy-FQGGWSDWSVMGATSkfaETPTAVFNpaTSAFELFGRGTDNSIWHAYNQN--GTGWSDWSVMNAsakfKG 358 Streptomycetaceae
WP_020516335 316 DGTLVHTWrnPNGTWGAWDSIGTWQi-dGEPAAVYEpnTGATEVFAKGNDGRLIRTWRNP--DGTWGAWGGIGTwh-lTS 391 Actinoplanes gl...
ONI85264     264 DNRLIHTYntAGAGWSEWHVLGGDWeiaSDPVAIYQphTRTTEVFARGMNGQLIHIWNTE--GSGWSEWHAIGDwh-iQG 340 Actinosynnema s...
RKT09791     378 VAHAYYTP--GMTDWSPWANIYDRKf-nGAPSALYNpaTDAVELFAIERNSTMYHTYWFNd-GKPWSDWLPLDGaa-fAG 452 Streptomyces sp...
WP_086785852 269 ADRLVHTWhaRGAGWSNWEVIGDVAl-kGDPAATYDaaTRTVEVFARDTADRLVHAWHEP--GKGWSGLEALHPdwrlAS 345 Crossiella equi
WP_089907768 209 LVTSWQSG--AGSGWSGWTALPTNAv--GTPSAHVDg-LGQMNVFTRRDDGHLIHLWQDGp-DGAIDRGADLGGd--fAG 280 Lentzea albida
WP_082874453 165 DPDHSMVG--GVLAHADFPPGCSVIt-tTLPKPVHF--DDSEHVWSVGAVASAFDIETVA--LHEFGHIVGLAH----TS 233 Arthrobacter sp...
WP_148641176 221 DGVMSHSYssNGGAWSDWATLGTNYhftGRPVAVYNpvTKVTEVFAVGTDGVMSHNYNFN--GGTWSGWSTLDTgykfTG 298 Streptomyces sp...

Feature 1                                                                                        
7BB4_A       220 DPVVINNC----DGRLEVFARGaDSTLRHISQIGSDs-VSWSNWQCLDG---VITSAPAAVKNi-SGQLEVFARGADNTL 290 Photorhabdus la...
WP_082559084 459 GATTVYNPd---TRTAEVFALRtDGVMAHLYNTNGE--GWSGWYALNPGg--VFVGRPAVLHNpvTNTLEVFATGTDASV 531 Kitasatospora s...
WP_020553691 359 APTAAYNPd---TQALELFALGtDNAVYHAYFQSAT--GWSEWSSMNVGf--KFKGTPSVAYNpaTHALELFALGTDGSV 431 Streptomycetaceae
WP_020516335 392 DPVAVYQPn---TQVAEVFARGsGDELIHTWRNPNGtwGAWDVVGEWDI---DGKPAAVYQPN--TQTTEVFAKGTDDRL 463 Actinoplanes gl...
ONI85264     341 TPSVVFQPn---TNTTEVFARGtNNQLIHVYNTNGGgwSEWHALGDWEL---ASDPVPLYQPN--TKTTEVFARGKSNQL 412 Actinosynnema s...
RKT09791     453 SPSLVYNPs---TKTAEVFATTtDGPLAHRYYTPGM--TGWSNWSTINGd-yRFAGAPSALYNpaTDAIELFATGRNSFL 526 Streptomyces sp...
WP_086785852 346 DPAPVFDPa---TATTEVFARGtDGTLIHTWHPPGK--GWAAFEVLPGG---TIQGTPFPVYEahSRTVEVFARDTADRL 417 Crossiella equi
WP_089907768 281 DPVVITKA----DGAKVVFLRGtDGRLWHKWQTGPG--SAFSDSALVRDdfgTIIGKPSVQVDa-EGRFTVFAVRSDNHL 353 Lentzea albida
WP_082874453 234 VANAVMAPtvsaNFTKRALTQD-DIDGFRALYPAAP--AAWSGWNSLGG---IITSDVTVANNk-DGRMEAFARGTDGAV 306 Arthrobacter sp...
WP_148641176 299 SPSAVYNAa---SNAIELFGIGaDGVMSHMYNINGGawSGWSTMGTFKF---AGTPTAVYNAD--TKTAEVFATGTDGVI 370 Streptomyces sp...

Feature 1                                                                                    
7BB4_A       291 WRTWQtsHNGPWSNWSSFTGi---IASAPTVAKNs-DGRIEVFVLGLDKALWHLWQTtsstTSSWTTWALIGGITL 362 Photorhabdus laumondii
WP_082559084 532 YRATWs-STTGWGPWTTTGSw--kFGSSPAAVYNpdTRTAEVFGQGTDGVMARLYNTn---GGGWSGWSVVGGIPT 601 Kitasatospora sp. M...
WP_020553691 432 WHNYIq-NGTAWEGWSVMDAgs-kFTAIPTAVFNpdTQAMELFGLGTDNAVWHNVFQe---STGWVGWSVMGLDFK 502 Streptomycetaceae
WP_020516335 464 IHTWRn-PNGTWGAWGAIGDw--kLSGDPVAVYQpnTQSTEVFARGNSGMLIHTWRMp---NGTWGTWANIGSYQM 533 Actinoplanes globis...
ONI85264     413 IHIWNt-EGSGWSEWHAIGDw--qFKGTPSAVFQptTNTTEVFARGMDNRLIHTYNTn---GSGWSEWFVLGGDWE 482 Actinosynnema sp. A...
RKT09791     527 YHAYWfnNGKPWSAWEALGDwrfaAGRIPTSLFStsSNTVDVFAGGADGAVNHTSYKp--gLPKWAPLDTLSGSTL 600 Streptomyces sp. 11...
WP_086785852 418 VHAWHp-PGKGWAGLEAVPGdw-rLASDPVAVYDpsTTTTEVFARGAQDELMHVWHQk---GAGWSNWEVLHSTWK 488 Crossiella equi
WP_089907768 354 ITAWQt-EPGGAFTTADLGGa---FAGDPVAISKa-NGAKVVFVRGTDGQLWHKWQTs--pGSAFSDSALVRGDLG 422 Lentzea albida
WP_082874453 307 WHRWQttPSGDWSGWNSLGGv---ITSEIAEGNNq-DGRLEIFARGTDNALWHRWQTt--pNGNWAGWNSLGGGIT 376 Arthrobacter sp. OY...
WP_148641176 371 SHAYSt-NGGAWSDWATLGTny-hFTGTPAIAYNpvNKVTEVFAVGTDGVMSHNYNVnd-vERLVDPRHRLQVHRQ 443 Streptomyces sp. CB...

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