Conserved Protein Domain Family
bile_salt_hydro

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NF038245: bile_salt_hydro 
choloylglycine hydrolase
Bile salt hydrolase, also known as choloylglycine hydrolase, enables commensal or pathogenic bacteria in the digestive tract to escape the antimicrobial activity of bile acids, which are cholesterol derivatives conjugated to glycine or taurine.
Statistics
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PSSM-Id: 468428
Aligned: 62 rows
Threshold Bit Score: 440.032
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009488525   1 MCTGLRFTDTAnNLYFGRNLDLDeNNYGEQPILAPEGYEMQYRHMPAKK-LSTAIIGMGVNAGGYPLFFEACSARGMGIA 79  Catellicoccus m...
WP_003415413   1 MCTALSIKADNgEYFFGRNMDLA-YEFNQCPMIIPRNYEIENKVTGEYLsNKYAIMAMGTIIDNHPALADGMNEKGLACA 79  Clostridium but...
WP_004031964   1 MCTTFSIQTEDgNNFVGRNLDLA-YNVNEYPIILPRNYLLQDKVTGDMQiTSKAIIGIGTVIDNHPSMVDAMNENGLVCA 79  Methanobacteriu...
WP_006785385   1 MCTAITLKTQDgLHALGRNLDIV-ALLDVAVILIPRSYAFTHTIMSLKKkNKYAMVGMSTTFENHVLLVDGMNEKGLACA 79  Turicibacter sa...
WP_012577775   1 MCTGVRFSDDEgNTYFGRNLDWS-FSYGETILVTPCGYHYDTVFGASGKaKPNAVIGVGVVMADRPMYFDCANEHGLAIA 79  Bifidobacterium...
WP_015449931   1 MCTGVRFADEDgNMYFGRNLDWS-FSYGEKIVVTPRGYQTPVAFNATVA-NPKPVMGVGIIVEGMPMYFDCANDEGLAVA 78  Bifidobacterium...
WP_012798358   1 MCTGIRFVDNDgNMYFGRNLDWS-CSYGEQVVITPTGYTPVSPFNAITE-IKHAVFGMGIVQQHVPLYFDCANDAGLAVA 78  Slackia heliotr...
WP_006294150   1 MCTGVRFTDADgNLYFGRNLDWT-VDYGEKVTMTPAGFTYQTKFGAPDG--KRAVLGMGITCDGIPLYFDCANENGLAVG 77  Bifidobacterium...
WP_009138584   1 MCTAVRFTDENgGLFFGRNLDWM-ESYGEKILATPRGFAYDYALGATHSeQPYAVVGVGCIMDSKPMYFDCANEAGLAVA 79  Slackia piriformis
WP_004217908   1 MCTAVRFDDGQnNMYFGRNLDWS-EDYGEKIVFAPHDYHYAPAFNAEDK--NHPVIGIGIIVEDTPLYFDCMNDAGLAVA 77  Bifidobacterium
WP_009488525  80 GLNFPRNAYFAPEGDQTkkYNVTPYEFMVWALDEFESVAELREALKDTYLIGTDFAPGMPLSPLHWIISDANETIVVEQT 159 Catellicoccus m...
WP_003415413  80 GLNFTGYGYFEEKPVEGk-INIAPYDFIGWILSNHTTVDEVREELSNLELVNVPINDKTPVSILHWMITDKSGKSIVVEK 158 Clostridium but...
WP_004031964  80 GLNFEGFAHFEEKPVPGk-TNITPYDFIYWVVSNYDTIDEVKSALSNIDLVDVPLNDQTPVPTLHWMITDKTGSSIVVEK 158 Methanobacteriu...
WP_006785385  80 VLELPKYASWSKVLDKDk-INVAPYDFVYWILANFQSLEEVKDGLKNVNLVNESLEGKEVSVDVHWIVTDRTGQSIVIEK 158 Turicibacter sa...
WP_012577775  80 GLNFPGYASFVHE-PVEgtENVATFEFPLWVARNFDSVDEVEEALRNVTLVSQIV-PGQQESLLHWFIGDGKRSIVVEQM 157 Bifidobacterium...
WP_015449931  79 GLNFPGYAQYADA-PVDgtVNVAAYELPFWIARSFSTVDEVEEALKNVTVVGKQVNEQYPVSFLHWIVGDGKRSIVIEAM 157 Bifidobacterium...
WP_012798358  79 GLNFPGYAQYAPN-AIDgkTNVAAYEFPLWVTASFRTVDEVEAALAHVAIVDEPINEKYPSSLLHWIIGDAKRSIVVEYT 157 Slackia heliotr...
WP_006294150  78 GLNFPGYAQYEEG-PVDgkTNVAAYEFPFWIARNFDTVDEAEAALKDVAIVGVPVSDEYPVSMLHWIIADKDRSIIVEYM 156 Bifidobacterium...
WP_009138584  80 GLNFPRCGAFPHE-PVEgkCSVATFEFPLWVARNFASTDEVEHALADTQIVSLVQ-PGQPESLPHWLIADSTRSIVVEST 157 Slackia piriformis
WP_004217908  78 GLNFAKYCKYATE-AVNftTNVAAYEFPLWVTRNFTSVDDVQEALKNVTIVGKPINDRFPVATLHWIIADNTRSIVVECT 156 Bifidobacterium
WP_009488525 160 KEKGLMVYENNVDVLTNNPEFPWHIQNLNNYIGLSANDRSNTTWNRQELQFQGIGTGQLGLPGDSSTQSRFVKTAFLNAN 239 Catellicoccus m...
WP_003415413 159 TKDKFAVYNNPVGVMTNNPTFDWHLTNLNEYVKLSPDNPSDTSWSDKKLSPLGIGAGTLGIPGDFASVSRFVRIAYIRAN 238 Clostridium but...
WP_004031964 159 TKEQLAVYDNPVGVMTNQPTFDWHLMNLNRYISINPNQPEPVKWSDQLLQIHGVGAGTLGLPGDSHSVSRFVRIAYARAH 238 Methanobacteriu...
WP_006785385 159 TKGNFRIYNNKVGVLTNAPTFDWHLINLNRYMNIQVTNPHKVKWGHQELSFDSEGFGGIGLPGDVSSSSRFVKAAFLRNH 238 Turicibacter sa...
WP_012577775 158 ADG-MHVHHDDVDVLTNQPTFDFHMENLRNYMCVSNEMAEPTSWGKASLTAWGAGVGMHGIPGDVSSPSRFVRVAYTNAH 236 Bifidobacterium...
WP_015449931 158 ADG-IHVHHDGVDVLANQPTFDWHTENLRNYLSMDPRVPEPVKWGTQELSAWGSGSGMRGIPGDYSSPSRFVRAAYTNAH 236 Bifidobacterium...
WP_012798358 158 ADG-MQVFHDEFDVLTNQPGFAWHAENLRNYINVTPGVPGPLSWGAGELTAYGSGGGMRGLPGDYYSPSRFVRVAYLNAH 236 Slackia heliotr...
WP_006294150 157 ADG-LHLYHNPVDVLTNQPTFGYHLENLRNYMGAKPEFPATETWDKLELTPWGSGTSMFGLPGDYSSPSRFVRAAYANAH 235 Bifidobacterium...
WP_009138584 158 KAG-LHVYENRADVLANSPELPWHIANLDNYLHTSNESPRPSSWGAQELRAWGIGAGMQGIPGDPSSPSRFVRAAYANAH 236 Slackia piriformis
WP_004217908 157 EDG-MHVYDDDVDVLTNQPPFPQQIEHLDNYAYVSPRTGKSVKWGSSELETNQDSNSSQGLPGGYGSMARFVRAAYNNTH 235 Bifidobacterium
WP_009488525 240 YPTQEGEEANVARMFNTLMDVAMPYGsvINEH--GAIEFTIYTSCYSQATQTYYYHIWNEAEIKHASITDENRKGTEIVT 317 Catellicoccus m...
WP_003415413 239 MPSIENDIKAITQFFHMLDYVKMVKG--GVITadGLEDLTLYSSCMDQEKGIYYYKNYNNSRINAVDMNKEDLNAKEIKK 316 Clostridium but...
WP_004031964 239 MPVLEDDISAVTQCMHMLDYVKMVKA--GVLTe-GMAEKTTYSACMDQENGIYYYKNYGNSRINAVNMHKEELDGDEVIK 315 Methanobacteriu...
WP_006785385 239 IRVEKGEDALITSTFHILSNVAVIKG--TAVTchQQYLKTQCTSCMCLETGVYYYNTYNNNQINAIHLFDENLDASEVKV 316 Turicibacter sa...
WP_012577775 237 YPQQNDEAANVSRLFHTLGSVQMVDGmaKMGN--GQFERTLFTSGYSSKTNTYYMNTYDDPAIRSYAMADYDMDSSELIS 314 Bifidobacterium...
WP_015449931 237 YPVQKTEESNVSRLFHTLDSAAMVDGcaLMSN--GQYEKTIYTSGFSAKTNTYYKNTYEDPAIKSYRMADFDLEGAQLQT 314 Bifidobacterium...
WP_012798358 237 YPRKDTEEENVSRLFHTLGGVSMVDGaaRMTN--GEFELTIYTGGVSCRTNTYYYSTYDDPAIRSVSLSDYDAQGCDLVI 314 Slackia heliotr...
WP_006294150 236 YPDMKGEKDNVQRLLKTLQNSAFILGgaEVAG--GQFEKTIYSSCYSALTNTYYYNTYEDYTVKAHALSDFDLTSDQIQQ 313 Bifidobacterium...
WP_009138584 237 HPAKTTERENVARLFRTLASVQITEGtaKSAE--GHFEKTIFTSGFSSSTNTYYANTYDDFEIRAFPFESFDLDGRELQT 314 Slackia piriformis
WP_004217908 236 YPTQSGENANVNRLFKTLSTAAVIEGtaISAN--GEFEKTLFSDCYSTATQTVYLKKYDDMAVHSYAVKDFDASSNQLQS 313 Bifidobacterium
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