1G6S,1UAE,1RF6,1RF5


Conserved Protein Domain Family
EPT-like

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cd01554: EPT-like 
Click on image for an interactive view with Cn3D
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Statistics
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PSSM-Id: 238795
Aligned: 4 rows
Threshold Bit Score: 552.211
Created: 12-Aug-2003
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Conserved Features/SitesClick to see Conserved Features Help
 
active sitehinge
Conserved site includes 11 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Structure:1G6S_A: Escherichia coli EPSP Synthase contacts with substrates shikimate-3-phosphate and glyphosate
  • Structure:1UAE: Escherichia coli Udp-N-Acetylglucosamine Enolpyruvyl Transferase contacts with substrate
  • Citation:PMID 1939260

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1               ##   #                                                                
1G6S_A     12 VDGTINLPGSKSVSNRALLLAALahGKTVLTNLLDSDDVRHMLNALTALGVSYTLsadrtRCEIIGnggplhaegalelf 91  Escherichia coli
1UAE       12 LQGEVTISGAKNAALPILFAALLaeEPVEIQNVPKLKDVDTSMKLLSQLGAKVERn---gSVHIDArdvnvfca---pyd 85  Escherichia coli
1RF6_A     10 LHGIIRVPGDKSISHRSIIFGSLaeGETKVYDILRGEDVLSTMQVFRDLGVEIEDkd--gVITVQGvgmaglkapqnaln 87  Streptococcus pneu...
1RF5_A     10 LHGIIRVPGDKSISHRSIIFGSLaeGETKVYDILRGEDVLSTMQVFRDLGVEIEDkd--gVITVQGvgmaglkapqnaln 87  Streptococcus pneu...
Feature 1          #                            #                                             
1G6S_A     92 lgnagTAMRPLAAALClg--sNDIVltgeprmkeRPIGHLVDALRLGGAKITyleqenyppl-rlqggftggNVDVDGsv 168 Escherichia coli
1UAE       86 lvktmRASIWALGPLVarfgqGQVSlpggctigaRPVDLHISGLEQLGATIKleegyvkas---vdgrlkgaHIVMDKv- 161 Escherichia coli
1RF6_A     88 mgnsgTSIRLISGVLAga--dFEVEmfgddslskRPMDRVTLPLKKMGVSISgqterdlpplrlkgtknlrpIHYELPia 165 Streptococcus pneu...
1RF5_A     88 mgnsgTSIRLISGVLAga--dFEVEmfgddslskRPMDRVTLPLKKMGVSISgqterdlpplrlkgtknlrpIHYELPia 165 Streptococcus pneu...
Feature 1      ##                            #                                                
1G6S_A    169 sSQFLTALLMTAPLApeDTVIrikgdlvskPYIDITLNLMKTFGVEIEnqhyqqFVVKGgqSYQSpgtYLVEGDASSASY 248 Escherichia coli
1UAE      162 sVGATVTIMCAATLAegTTIIena---arePEIVDTANFLITLGAKISgqgtdrIVIEGveRLGGg-vYRVLPDRIETGT 237 Escherichia coli
1RF6_A    166 sAQVKSALMFAALQAkgESVIie-----keYTRNHTEDMLQQFGGHLSvdg-kkITVQGpqKLTGq-kVVVPGDISSAAF 238 Streptococcus pneu...
1RF5_A    166 sAQVKSALMFAALQAkgESVIie-----keYTRNHTEDMLQQFGGHLSvdg-kkITVQGpqKLTGq-kVVVPGDISSAAF 238 Streptococcus pneu...
Feature 1                                                                                   # 
1G6S_A    249 FLAAAAIKg-gTVKVTGIgrnsmqgdirFADVLEKMGATICWGd-------dYISCTRg--eLNAIDMDMNh----iPDA 314 Escherichia coli
1UAE      238 FLVAAAISr-gKIICRNAqpdt---ldaVLAKLRDAGADIEVGe-------dWISLDMhgkrPKAVNVRTAphpafpTDM 306 Escherichia coli
1RF6_A    239 WLVAGLIApnsRLVLQNVgine--trtgIIDVIRAMGGKLEITeidpvaksaTLIVESs--dLKGTEICGAlip-rlIDE 313 Streptococcus pneu...
1RF5_A    239 WLVAGLIApnsRLVLQNVgine--trtgIIDVIRAMGGKLEITeidpvaksaTLIVESs--dLKGTEICGAlip-rlIDE 313 Streptococcus pneu...
Feature 1                                                                            #        
1G6S_A    315 AMTIATAALFAKGTTTLRniynwrvketdrlFAMATELRKVGAEVEEGHDYIRITPpekLNFAEIAtyndhRMAMCFSLv 394 Escherichia coli
1UAE      307 QAQFTLLNLVAEGTGFITetvf------enrFMHVPELSRMGAHAEIESNTVICHGvekLSGAQVMat-dlRASASLVLa 379 Escherichia coli
1RF6_A    314 LPIIALLATQAQGVTVIKdaeelkvketdriQVVADALNSMGADITPTADGMIIKGksaLHGARVNtfgdhRIGMMTAIa 393 Streptococcus pneu...
1RF5_A    314 LPIIALLATQAQGVTVIKdaeelkvketdriQVVADALNSMGADITPTADGMIIKGksaLHGARVNtfgdhRIGMMTAIa 393 Streptococcus pneu...
Feature 1                       #            
1G6S_A    395 al--sdTPVTILDPKCTAKTFPDYFEQLARI 423 Escherichia coli
1UAE      380 gc-iaeGTTVVDRIYHIDRGYERIEDKLRAL 409 Escherichia coli
1RF6_A    394 allvadGEVELDRAEAINTSYPSFFDDLESL 424 Streptococcus pneumoniae
1RF5_A    394 allvadGEVELDRAEAINTSYPSFFDDLESL 424 Streptococcus pneumoniae

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