Conserved Protein Domain Family
DPH5

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COG1798: DPH5 
Diphthamide biosynthesis methyltransferase [Translation, ribosomal structure and biogenesis]
Statistics
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PSSM-Id: 441403
Aligned: 80 rows
Threshold Bit Score: 245.871
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_014026634   2 PLFIAGFGTSIEYVTLRLLDVLREADKVYIDAYTSI---APGLDADSVARLaP--RAEIVIADRKLLEEkq-sVIIEEAR 75 
BAA79915       9 TLLLVGWGYAPGMQTLEALDAVRRADVVYVESYTMP---GSSWLYKSVVEA-Ag-EARVVEASRRDLEErs-rEIVSRAL 82 
ACR41861       3 ILSLVGLGISKKFITENAIDTLNNSDIIIFDKYTSR---SCDINVDVLRRL-VkgGKTLIEADRSLLENns-kIIMDYLD 77 
ADM26901       1 MLRFIGLGLSIDNIPIGNLKKLFECQKIFIDSYTSIwfpNIDLLVDILVKS----GKSVVVARRDDLEGsairRILSESR 76 
AFH43009      18 ELSFVGLGLSLSHISIEGIKKLKSSDFIFLEGYTSF---YFPEINAAMKVIgIk-SDRFKIISRRDIEEksgqEIIDLLL 93 
AMD29695       1 MFILSGIGQNKDEIPYGLIEEIKIADLVFLEYYTNF---IDEETKEFLLNI----RKDIKIVDRNFVELel-eKIILNNK 72 
WP_010979297   3 TLKLIGLGLSAKFVTREAIDEISKCNVVLFESYTSL---SCDINLDFIKFL----NKNVIIVDRKFIENni-kEIIKLLK 74 
WP_011278171   3 VLKLIGLGLSYKFITEIALNELRTSDVVYADTYTSL---TCGDLISRLHQL----GINPIPVGRDFIENny-kKILELLD 74 
WP_013337125   7 TLYIVGLGLSPANITAEALEVIRSVDVVFLEMYTSK---GPAEFMDQLRSI----RGDLIQVSRRDLEDmnseIIMRVLE 79 
WP_126449903   6 RLYLVGLGLSSNFLTQATLDALRSSDVIFLDGYTSI---SCDLNAELISKL-T--SKEVIVAKRSQLEDea-kQLLKLAE 78 
WP_014026634  76 E-KNIVVLVPGDPMLATTHVTLRIEAVRRGVSVELIHGVSGLQAVVSYTGLQVYRFGRTVTLVYPEEgf-kPYSTVEYTW 153
BAA79915      83 D-AVVAVVTAGDPMVATTHSSLAAEALEAGVAVRYIPGVSGVQAARGATMLSFYRFGGTVTLPGPWRgv-tPISVARRIY 160
ACR41861      78 KnYNVSIASIGDVLIATTHVSLLIEAKQRGHNVKVIPGISVHCYLISKSLLSSYKFGKSVTVTFPYNdf-iDPTPYNVIK 156
ADM26901      77 D-YDICIATPGDPFIATTHSAILSEALRMGIAVEISPSSSIVNVGISMSCLQIYRFGKIVTVVRPKNgi-vYEYPFDVLK 154
AFH43009      94 KgKNISMAVIGDPFIATTHLSLKNYAKEKGCKVNYIPGINIFSYAMSATGLFNYKFGPSATIVYKREgi-lSVYPYLVLS 172
AMD29695      73 D-KKIILITSGNPLFATTHMYFIELCKKNNIEYKIINSPSIFDEI-GKIGLFLYKFGRTVSISFHE-----STEFYDYII 145
WP_010979297  75 EkEDVCIVTIGDPMIATTHVSLIVEVKDKGYNFKVIPGISVHCYIISKSMLSSYKFGKSVTITYPYNnk-iDTTPYDVIY 153
WP_011278171  75 QgKSVGIAVIGDPMIATTHISLVTEARTKGHQVSIIPGVSVHCYIISKSMLSSYKFGKSVTIISSTDygkiDTTPYKVLK 154
WP_013337125  80 GgRNAALLVIGDPMIATTHAVIAVIAKRRGFNVRVINSVSIVCAVLSQLGLSPYKLGPVATITYPRMgv-lSMRAYEVLS 158
WP_126449903  79 LgNVVSIASIGDPMIATTHAALAVDAMSRGIEVKIVPGISVFCYAVSKSMLSSYKFGRSVTITYPTgi--aDVTAIKVIE 156
WP_014026634 154 ENLDRGLHTLILLDLRLDqgRAMSINEAIPILLELEDElvsqtGRKE-----RLIRDSILVGVARAGTREAKCRAGKAEE 228
BAA79915     161 LNLCAGLHTTALLDVDERg-VQLSPGQGVSLLLEADRE-----YAREagapaLLARLPSVLVEAGAGGGHRVLYWSSLER 234
ACR41861     157 DNKERGLHTILYLDLKSE--KAMTANEALQILLRLEDK-----HRKN-----VLSKSDIVIVGARLGCDDEKIVALTVEE 224
ADM26901     155 LNRELNLHTLMLLEIDVEnnYYMNPREAIEILLEIQRM-----RGEE-----ILGKDDKIIVLEALMSSSGRIYIESVES 224
AFH43009     173 GNLSRGLHTFFFLDIDAEr-GPLNASEAIKLLIEMEKE-----ERLG-----IITPETKIVVLERLGWPDEKIYYGKISL 241
AMD29695     146 RNYKNNLHTLVLLDLDPInnRYLDHKEAIKRLLEIDNK------REK-----IFNDNFKLIVCSNLNRKNEKIYYKEIKE 214
WP_010979297 154 DNFIRGLHTILYLDLKED--KIMTAKEAVELLIEMEKI-----KKQG-----LVSDDRIIIVGQRLGCDDEEVVALRLKE 221
WP_011278171 155 ENLERNLHTIFYLEPN------MSARDAVSLLLQMEKI-----EEQG-----IINEDSLIIVGQHLGCDDEEIVSLKIKE 218
WP_013337125 159 DNLIRGLHTILLLDIKDDg-SFMSASEAVELLKKMEDN-----GKLG-----IISKDLAVVYAARIGWGNQSIKVSTIED 227
WP_126449903 157 SNFSQGLHTLTFLDIKDD--KPMRVSEAFDVLREQQSR-----LGRD-----VLGQFQYVVVESRLGCPDEKVSVISVNE 224
WP_014026634 229 VASEA---YPPPPHSLIVTApRLHPIEEEALHLICNL 262
BAA79915     235 LSTAD---VEGGVYSIVIPA-RLSGVEEWLLAAASGQ 267
ACR41861     225 ATLYD---FGNTPHIIIIPG-NLHYMEADAIKWMLMS 257
ADM26901     225 ILRRSpdeYRFYPYTIIIPArVLHPIERECLENIDRV 261
AFH43009     242 LYNMR---F-NPPNSIIIPG-KLHFMEEQSLEAFSIE 273
AMD29695     215 LLNIN---L-DPPICIIIPS-NLNKIELEFLLCMIS- 245
WP_010979297 222 VFNYK---FKEPPHIIVFPTdKLHFMEVEALKCLMK- 254
WP_011278171 219 IAKYN---LKSPPHIIIFPSkSLHYMEIEGLKWLMK- 251
WP_013337125 228 VPN-----IGETPHTIVIPG-LLNPVEQEYLVNVLGA 258
WP_126449903 225 A-DED---VGSPPYVIIFPS-RLHFMEVDALKWLRFK 256
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