1EHH,1WGT,1IQB,1ENM,1WKX,1ULM,1ULN,2LB7,1ULK,1EHH,1IQB,1ULM,1ULK,1P9G


Conserved Protein Domain Family
ChtBD1

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cd00035: ChtBD1 
Click on image for an interactive view with Cn3D
Hevein or type 1 chitin binding domain
Hevein or type 1 chitin binding domain (ChtBD1), a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins such as hevein, a major IgE-binding allergen in natural rubber latex, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.
Statistics
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PSSM-Id: 211311
Aligned: 31 rows
Threshold Bit Score: 33.8982
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
carbohydrate
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:carbohydrate binding site [chemical binding site]
Evidence:
  • Structure:1EHH: Urtica dioica agglutinin binds tri-N-acetylchitotriose, contacts at 4 A
  • Comment:Sequence variations in the binding site can affect binding specificity and binding affinity.
  • Comment:Glycines stabilize the site and may not directly contact the substrate
  • Structure:1ENM: Urtica dioica agglutinin binds N-acetyl-D-glucosamine, contacts at 4 A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                            # ### #    #               
1EHH_A         2 RCGSqggGATCPg---LRCCSIWGWCGDSePYCGr-tCEn----KCW 40   great nettle
1ULM_A         3 ECGErasGKRCPn---GKCCSQWGYCGTTdNYCGq-gCQs----QCD 41   American pokeweed
1ULN_A         3 ECGErasGKRCPn---GKCCSQWGYCGTTdNYCGq-gCQs----QCD 41   American pokeweed
Q9AVB0       255 RCGRnfgFRTCPn---ELCCSSGGWCGSNdAHCGk-gCQs----QCD 293  American pokeweed
Q9AVB0        44 ECGReasGKVCPd---DLCCSVFGHCGVSvQHCGd-gCQs----QCV 82   American pokeweed
1EHH_A        48 RCGAavgNPPCGq---DRCCSVHGWCGGGnDYCSggkCQy----RCS 87   great nettle
1ULM_A        44 RCGRdfgGRLCEe---DMCCSKYGWCGYSdDHCEd-gCQs----QCD 82   American pokeweed
XP_001754906  23 DCGWqanGARCSp--sTVCCSQWGYCGVTpEHCGt-gCQs---gSCT 63   Physcomitrella patens subsp. patens
XP_384927    420 ECGSr-nGRTCAgsglGNCCSANGYCGSTgSHCGq-gCQkgassACL 464  Gibberella zeae PH-1
1ULK_A        85 RCGKdfgGRLCTe---DMCCSQYGWCGLTdDHCEd-gCQs----QCD 123  American pokeweed

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