6FHW_A 40 AIALQGALNNIGPDGSAVPGAGAGFVVASPSKANPdyf---------ytWSRDSALTLKMII---------------DEF 95 creosote fungus Q9W391 8 GVRLDYYQRIVHRLILAHQEPVTGLFPASNVNSHA--------------WIRDNVYCILAVWglsmaykkiadqdedRAK 73 fruit fly Q9VLS1 48 VKQLDIYYGIVKRQLLRYQSPITGLFPVMSTdqv-------------vgSVRDSVYCASAVWslyqay---rridddRGK 111 fruit fly Q8YW30 8 QARLEYYYQQIKTVIMIRQNPITGLLPASTAITAHgdy--------tdaWVRDNVYSILAVWglalay---rkvdedQGR 76 Nostoc sp. PCC 7120 Q97V93 207 KSFNDLYKASIYTMLGSIYAP-SGGVIAAPTTSLPeveggkrnwdyrfaWVRDSSIIAEALLeags-------iveaRRI 278 Saccharolobus solfa... Q10211 255 GRYREFVQRNALTLKLLIYEP-TGAVIASPTFSLPedlggvrnwdyrftWIRDSAFTIYALAqlgf-------raeaVEY 326 Schizosaccharomyces... Q9HLE2 203 GMYHSMVMRSALALKVLFYEP-TGMMVAAPTASLPeaiggernwdyrytWIRDTAYVIEALAtigy-------kreaVSF 274 Thermoplasma acidop... Q9KYJ7 222 GPYREAVVRSSIALKAMTYGP-SGGIVAAPTTSLPeeiggqrnwdyrysWLRDASTTLAALLgtgy-------lqeaQAW 293 Streptomyces coelic... Q9S223 231 GPYREAVVRSLITLKALTYAP-TGGIVAAPTTSLPediggvrnwdyrytWLRDAAITLSSLLrtgy-------reeaRAW 302 Streptomyces coelic... Q9RJ38 216 GPHRDAVVRSLITLKALTYQP-TGGIVAAPTTSLPeepggvrnwdyrfcWLRDSTLTLGALLsagy-------leeaEAW 287 Streptomyces coelic...
6FHW_A 96 ILG-NTTLQTIIEQ-YIHAQAVLQTVSNPSGTFLPDgvGLGEPKFMVDGTRFNGP--WGRPQRDGPALRAIALMTYsnwl 171 creosote fungus Q9W391 74 CYElEQSCVKLMRG-LLMAMMNQKDKVEKFKMTQSPydSLHAKYSSKNGLPVVDDneWGHLQIDAVSLYLLILAQM---- 148 fruit fly Q9VLS1 112 SYElGQSTVKCMRG-ILECWVKQASRVELFKQRQSNqhALHSKFQLHTGEKIYPDefYNHLQIDCVSLYLLFLVQM---- 186 fruit fly Q8YW30 77 TYElEHSVIKLMRG-LLFAMMRQAHKVEQFKQTQSPldGLHAKYNTATGDIVVGDdeWGHLQLDATSIFLLMLAQM---- 151 Nostoc sp. PCC 7120 Q97V93 279 INFlLSLINFSSKP-FYYPLYTIEGT-IPPPERELR----WLSGYKNSKPVRIGNgaSSQIQLDIEGFFISALYKYv--k 350 Saccharolobus solfa... Q10211 327 MSFiYHVLKKKNKDgGINIVYSIHGDSQNLEEVELT----HLRGYYNSHPVRIGNaaVHHLQLDIYGELMDSIYIY---- 398 Schizosaccharomyces... Q9HLE2 275 LYDmMDVISRENK---IRTIYSIDNS-DDFVEREL-----DFEGYRGSRPVRIGNkaVDQLQIDQYGSIVRAIHAM---- 341 Thermoplasma acidop... Q9KYJ7 294 RRWlLRAVAGDPEN--LQIMYGITGD-RDLRERELP----WLPGYEGSSPVRVGNgaADQLQLDVYGEVIDTLYLA---- 362 Streptomyces coelic... Q9S223 303 REWlLRAVAGDPEN--LQIMYGIAGE-RELGEAELD----WLPGYEGSGPVRVGNgaAHQLQLDVYGEVTEALHLG---- 371 Streptomyces coelic... Q9RJ38 288 RDWlLRAVAGNPAD--LQIMYGVAGE-RRLPEYELP----WLSGFAGSAPVRIGNdaVNQLQLDVYGEVMDSLSLA---- 356 Streptomyces coelic...
6FHW_A 172 IKNGqfAEAKTKIWPI--IANDLSYVGQYWNQSGFDLWE----ETYASSFF--TIQNQHRALVEGAQLAHDLG--V---- 237 creosote fungus Q9W391 149 TASG--LQIVFSLDEVsfIQNLVFYIESAYSIPDYGIWErgdkTNHGEPELnaSSIGMAKAALEAMNELDLFGarGgpas 226 fruit fly Q9VLS1 187 ITSG--LQIIYTHDEVafVQNLVYYVERAYRTPDFGMWErgskYNNGTPEIhaSSIGMAKSALEAINGCNLFGekGasws 264 fruit fly Q8YW30 152 TASG--LQIIYTIDEVnfVQNLVYYIGRAYRTPDYGIWErgnkINHGNAELnaSSVGMAKAALEAMNELDLFGvrGsqas 229 Nostoc sp. PCC 7120 Q97V93 351 MTND--QVFLKDVFSK--VKYIGDWISENWSLKDSGIWE----DRGSPQHYthSKIMMWIALDKIGKLANLIG------- 415 Saccharolobus solfa... Q10211 399 DKKC--QPIAYDLWLE--VRQICDYVCANWKRPDKSIWE----VRGQERNFlySKIMLWVALDRALRIAFTRSlpC---- 466 Schizosaccharomyces... Q9HLE2 342 EKAG--GVVNSYLWDF--VEEMMAKIEYLWKYPDSSIWE----FRTEPKQYvySKVMSWAAFDSAITMARDLGltA---- 409 Thermoplasma acidop... Q9KYJ7 363 YQSG--VAHCADTAVL--HRQLIQHLARRWREPDEGIWE----IRGARRHFvhSKVMAWVAVDRTIRLAEAGAldM---- 430 Streptomyces coelic... Q9S223 372 HMTG--LARNDYASVL--QLKLIRYLEDHWNEPDEGIWE----VRGPRRHFvhSKVMAWVAVDRTIKLIESGDadG---- 439 Streptomyces coelic... Q9RJ38 357 RLAG--MRPRPQMWEL--QCALMEFLATAWREPDEGLWE----VRGGRRQFvhSKVMTWVALDRAVRTLEDRPelG---- 424 Streptomyces coelic...
6FHW_A 238 ---------------------------------------------TCTG--CD-QAPEVLCFL-------Q----SF--- 255 creosote fungus Q9W391 227 vihvladeahkcqavlqsmlpresnskeldsgllcvigfpafavdDAQL--IHnTKDAILSRLqgkygckRflrdGYrtp 304 fruit fly Q9VLS1 265 vvyvdidahnrnrsifetmlpressskgvdasllltlsfpafashEDRL--VEqTKQNVVNRLrckmgfkRftrdGFlsk 342 fruit fly Q8YW30 230 vihvlpdeiartrstlesllpresaskeidaallsiisypafaveDAQL--RErTLNEIINKLqgkygckRflrdGHqtv 307 Nostoc sp. PCC 7120 Q97V93 416 ---------------------------------------------YADI--WAkEREKLRNWIftn--cvK--------- 437 Saccharolobus solfa... Q10211 467 ---------------------------------------------PKHMv-WMdTRDEIYEAIm-----dS----GY--- 488 Schizosaccharomyces... Q9HLE2 410 ---------------------------------------------PIKK--WKgIQDEIWNDVm-----tK----GF--- 430 Thermoplasma acidop... Q9KYJ7 431 ---------------------------------------------DVAP--LVeLRAAIHREVc-----dK----GF--- 451 Streptomyces coelic... Q9S223 440 ---------------------------------------------PLER--WKqLRDDIHRDVc-----eK----GY--- 460 Streptomyces coelic... Q9RJ38 425 ---------------------------------------------GGDLdgWRaLRDEVHREVc-----eK----GY--- 447 Streptomyces coelic...
6FHW_A 256 -----------------------WNGKYIVSNINVN---------NGRTGLDGNS--------------ILGAISTFDID 289 creosote fungus Q9W391 305 kedpsrlyyerwelrmfenieceWPLFYCYLILFHAfqsdkraveEYASRLEKIMvrse-------dgiLLVPESYAVPQ 377 fruit fly Q9VLS1 343 nedksrryyhsgelkefegleceWPLFFIAMIIDGVfknnneqieEFQNDLRRCLrtd--------vngDPVVTMYYAPD 414 fruit fly Q8YW30 308 ledtqrlhyepwelkqfehieceWPLFFTYLALDGLfcddskqaqFYQEQLEKLLierdgvsanighslRLLPELYYVPA 387 Nostoc sp. PCC 7120 Q97V93 438 --------------------------NNYFIRYCGN-----------TDDVDSSL--------------LSAPLYGFIEV 466 Saccharolobus solfa... Q10211 489 -----------------------NMEKGFFAQSFEN-----------NDILDASV--------------LVMPLVSFISP 520 Schizosaccharomyces... Q9HLE2 431 -----------------------DPQTNSFVQYYGS------------KNVDASL--------------LRLPILGFIPA 461 Thermoplasma acidop... Q9KYJ7 452 -----------------------DPVRNTFTQAYGS------------QELDAAT--------------LLIPRTGFLPP 482 Streptomyces coelic... Q9S223 461 -----------------------DKERNTFTQSYGS------------QALDASL--------------LLIPQMGFLPP 491 Streptomyces coelic... Q9RJ38 448 -----------------------DPVRNTFTQYYGS------------RELDASV--------------LLIPRVGFLPP 478 Streptomyces coelic...
6FHW_A 290 AYcdspt---------lqpchSQSLANFKVLTDT-FRNLYTINAGIPEGQgvaVGR-YAEDVYM---------------- 342 creosote fungus Q9W391 378 DLvgfeyqkpgsqvrevvgrcPFLWGQSLFILGR-LLQEGFLAVGELDPL---NRR-LGAQKKPdvvvqvviiaedneir 452 fruit fly Q9VLS1 415 GDgsymr---------apsqsLFLWGQSFFIIAQ-LLTAGLLHINELDP----IRRyLPSYNRPrragrysafqgtatdl 480 fruit fly Q8YW30 388 ENveaeklapqtqprlpnenvPLVWAQSLYYLGQ-MLSEGLLAVGDVDPL---GRH-LTIGKKRealvqivllaededlq 462 Nostoc sp. PCC 7120 Q97V93 467 SD-------------------STFINTLTKIEND-LKTDVF------------VKR-YKTDFmg---------------- 497 Saccharolobus solfa... Q10211 521 TD-------------------PRFLSTMDNIMKP-LEKDGLMSNGL-------IFR-YNNFVYEdgv------------- 559 Schizosaccharomyces... Q9HLE2 462 ND-------------------ERFIGTMKRIEDE-LMVDGYL-----------FRR-YREDdgl---------------- 493 Thermoplasma acidop... Q9KYJ7 483 DD-------------------PRVIGTVDAVRRE-LSTD----DGL-------VYR-YPTCSEDagad------------ 518 Streptomyces coelic... Q9S223 492 DD-------------------KRVIGTIEAIQRElSTSDGF------------ILR-YPTDGEAegvd------------ 527 Streptomyces coelic... Q9RJ38 479 DD-------------------PRVVGTVDAIGAE-LARDGL------------VRR-YSTEGDPvdg------------- 512 Streptomyces coelic...
6FHW_A 343 --------------------------------------------------------GGNPW------------------- 347 creosote fungus Q9W391 453 dklaehdlhvqti--------------aevapievqparvlshlytylgrnrklglSGRKSrdvgilstsklyslkdrif 518 fruit fly Q9VLS1 481 vvqivliaesmrlqammatygiqtqtphevepvqiwsstelikvyqhlgvnnkvglSGRPCrpvgslgtskvyricgmtv 560 fruit fly Q8YW30 463 aqlavhgietqtp--------------kqvapiqvrqaselstiytqigrndklglTGRPVrrlrslttsrvfrlrgeti 528 Nostoc sp. PCC 7120 Q97V93 498 -------------------------------------------------------eAKHPF------------------- 503 Saccharolobus solfa... Q10211 560 ------------------------------------------------------ggDEGAF------------------- 566 Schizosaccharomyces... Q9HLE2 494 ------------------------------------------------------kgDEGSF------------------- 500 Thermoplasma acidop... Q9KYJ7 519 ----------------------------------------------------gltgDEGAF------------------- 527 Streptomyces coelic... Q9S223 528 ----------------------------------------------------glpgDEGAF------------------- 536 Streptomyces coelic... Q9RJ38 513 -----------------------------------------------------lpgGEGTF------------------- 520 Streptomyces coelic...
6FHW_A 348 ------------------------------YLITTA-------------------------------------------- 353 creosote fungus Q9W391 519 aftpqfadlsrfyiasdnelmidilkgeinFLKSAWdllgrplvtlvlkrihldqdkiplamiqtmrklksgyingtrvm 598 fruit fly Q9VLS1 561 lcyplifevsdfylyrdmalliddiktelqFVGKYWrlsgrptvcllireehmrdpqfkemldllamlkkgycdgmkvri 640 fruit fly Q8YW30 529 vflpsfldsqqfyltldyhflvdqirselaYIQKYWsdlgrpiltlmlthtmletgsqallelmqelkdgvcngvavklg 608 Nostoc sp. PCC 7120 Q97V93 504 ------------------------------LLTTVW-------------------------------------------- 509 Saccharolobus solfa... Q10211 567 ------------------------------TMVCFW-------------------------------------------- 572 Schizosaccharomyces... Q9HLE2 501 ------------------------------LMLTFW-------------------------------------------- 506 Thermoplasma acidop... Q9KYJ7 528 ------------------------------FLCAFW-------------------------------------------- 533 Streptomyces coelic... Q9S223 537 ------------------------------LACSFW-------------------------------------------- 542 Streptomyces coelic... Q9RJ38 521 ------------------------------LVCSFW-------------------------------------------- 526 Streptomyces coelic...
6FHW_A -------------------------------------------------------------------------------- creosote fungus Q9W391 599 lgslkdflntsaitdlsflgstedgypdrlhpdvqtyldehllrsfsnrstmnlrggqlrprtlrrrmsckgaikktrsi 678 fruit fly Q9VLS1 641 grlqnlisssciehldfmnqsdltdnenaf-------------------------------------------------- 670 fruit fly Q8YW30 609 rlnqlmltgaiqridflqdvefyqsavqd--------------------------------------------------- 637 Nostoc sp. PCC 7120 Q97V93 -------------------------------------------------------------------------------- Saccharolobus solfa... Q10211 -------------------------------------------------------------------------------- Schizosaccharomyces... Q9HLE2 -------------------------------------------------------------------------------- Thermoplasma acidop... Q9KYJ7 -------------------------------------------------------------------------------- Streptomyces coelic... Q9S223 -------------------------------------------------------------------------------- Streptomyces coelic... Q9RJ38 -------------------------------------------------------------------------------- Streptomyces coelic...
6FHW_A -------------------------------------------------------------------------------- creosote fungus Q9W391 679 nvdsdnlgmegpsplterrlssivpppwlqankqshvsvfattpeegptssplslgndlireniypvdphhsrsaidrrs 758 fruit fly Q9VLS1 -------------------------------------------------------------------------------- fruit fly Q8YW30 -------------------------------------------------------------------------------- Nostoc sp. PCC 7120 Q97V93 -------------------------------------------------------------------------------- Saccharolobus solfa... Q10211 -------------------------------------------------------------------------------- Schizosaccharomyces... Q9HLE2 -------------------------------------------------------------------------------- Thermoplasma acidop... Q9KYJ7 -------------------------------------------------------------------------------- Streptomyces coelic... Q9S223 -------------------------------------------------------------------------------- Streptomyces coelic... Q9RJ38 -------------------------------------------------------------------------------- Streptomyces coelic...
6FHW_A -------------------------------------------------------------------------------- creosote fungus Q9W391 759 efvrqqempkiliqrhraetnfadteveeliamlretenleeqgdilqylvdtqgldfntaglgfknkseenatpnanna 838 fruit fly Q9VLS1 671 ----------------sqinheyigyqsltdvpkaltyveekisvahfdtkptpdiinalrstdsiyclcqlwgiilnre 734 fruit fly Q8YW30 638 ----------------agkrcyylayhpgknwrlghsqefqveyetnldfllsslrasenlyeqiellqtltrlqglefd 701 Nostoc sp. PCC 7120 Q97V93 -------------------------------------------------------------------------------- Saccharolobus solfa... Q10211 -------------------------------------------------------------------------------- Schizosaccharomyces... Q9HLE2 -------------------------------------------------------------------------------- Thermoplasma acidop... Q9KYJ7 -------------------------------------------------------------------------------- Streptomyces coelic... Q9S223 -------------------------------------------------------------------------------- Streptomyces coelic... Q9RJ38 -------------------------------------------------------------------------------- Streptomyces coelic...
6FHW_A 354 ---------AAEFLYDAVAQWKARHV-LTVDETSLAFFKDIYPE----------------VTVREYKsgnaNSPFAQIMD 407 creosote fungus Q9W391 839 gmleegrvvTVRDLLKGLYEKACQQKlWGLVRHTAGMLGKRVEDlakavtdl-lvrqkqvTVGMPPN----NEHTITAPL 913 fruit fly Q9VLS1 735 gphfevnglNVNTALTQLYHRAGSLRyWRAVRYCSSLLHHIVDSispfittv-lvngkelTVGIIGQ----KETVFDKPM 809 fruit fly Q8YW30 702 tgfgtnqrvTVADLLDEVYTKAGELGfWAVVRRAAG-LRQMVDIgltdavtsilirgkqiAVGRAYS----EASLISVPM 776 Nostoc sp. PCC 7120 Q97V93 510 --------------LARVYMRLGK------IDSAIEILNKINKV------------------------------------ 533 Saccharolobus solfa... Q10211 573 --------------LVEALAMAGCSGyPKLLSTAVSMFEDLVRY------------------------------------ 602 Schizosaccharomyces... Q9HLE2 507 --------------YIEDLILMKR------LKAARAALESIIEK------------------------------------ 530 Thermoplasma acidop... Q9KYJ7 534 --------------FVDGLALTGR------LDEARALFERLLAL------------------------------------ 557 Streptomyces coelic... Q9S223 543 --------------MADDLAMIGR------VDEARKLFEKLLSL------------------------------------ 566 Streptomyces coelic... Q9RJ38 527 --------------YADALHATGR------TKEARELFERLVGL------------------------------------ 550 Streptomyces coelic...
6FHW_A 408 AVTAYADSYVAIAEKyIPSNGSLSEQFNRDTGTPLSAIDLTWSYAAFITMSQ 459 creosote fungus Q9W391 914 PEVELRQLIHDAYGD-DESTAMLTQELMVYLAMFIRTEPQLFHEMLRLRVGL 964 fruit fly Q9VLS1 810 TPAEIQNVMYTSVQPyDVIQAVLQQEVVLYCGRLIATNPSMFRGILKIRIGW 861 fruit fly Q8YW30 777 PHNEIADKINHFCRE-DIRDRVLTQEVLIYLGILIRSQTESFQGLLTLRVGY 827 Nostoc sp. PCC 7120 Q97V93 534 ----------------SRELHLVGEHVDVEKGEFTGNFPQIFVHAQLVIAIK 569 Saccharolobus solfataricus Q10211 603 ----------------SSHLQYYSEECSL-SSESLGNSPQAFSSIAAIAAAH 637 Schizosaccharomyces pombe 972h- Q9HLE2 531 ----------------ANHLGLYSEEIDEKTGDFLGNFPQALSHLGIIRVAP 566 Thermoplasma acidophilum DSM 1728 Q9KYJ7 558 ----------------RNDLGLLAEEYDPVQQRQLGNFPQAFSHMGLIQSAL 593 Streptomyces coelicolor Q9S223 567 ----------------RNDLGLLAEEWDPRLQRQVGNFPQAFSHVPLIDTAL 602 Streptomyces coelicolor Q9RJ38 551 ----------------ANDVGLLAEEYDPVAGHQLGNFPQAFSHVGLVNTAL 586 Streptomyces coelicolor
Jiyao W et al.(2023). "The conserved domain database in 2023.",