2K7M


Conserved Protein Domain Family
Connexin40_C

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pfam16791: Connexin40_C 
Connexin 40 C-terminal domain
This is the C-terminal domain of connexin 40. It interacts with the C-terminal and cytoplasmic loop domains of connexin 43 and with the cytoplasmic loop pf connexin 40.
Statistics
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PSSM-Id: 465272
Aligned: 19 rows
Threshold Bit Score: 74.773
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2K7M_A         8 LVQGLTPPPDFNQCL------KNSPDeKF----------FSDF------SNNMGSRKNPDPLATEEVpn-qEQIPEEG-F 63 
XP_007251416 277 PDRACTPPPSFSESL------ATSSPpRHplhphphhpsCPPF------NNRLAHQQNSVNFATERHrg-hDDSLGTEdF 343
AAI63086     259 PNRACTPPPDFNQCL------TSPPSsPTlqthsllhptCPPF------HDRLAHQQNSANMVTERHrg-qDYL--GVnF 323
XP_015219426 256 PSRACTPPPDFNQCV------TAPETg------------CNPF------NNKMANQQNSVNLATERHqs-rDNLDGEd-F 309
XP_006011654 269 PSGSYTPPPDFNHCV------NS-PNgKY-----------NPF------NNKLASQQNSTNFATEQDqs-qEEL-GSGqF 322
XP_005167744 273 LSQTCTPPPDFNQCLrsnqgpTSPPHl-HshhlhhihqtCQPF------TNHLAHQQNSVNMAAERHhhshDGLEPAVdF 345
XP_005799418 268 PSASCTPPPDFDHCL------TAPRSmNPmts-----iaSHPF------NTRMALQQNSANLATERHhs-cDNLEDEEdF 329
XP_011488177 260 ESAPCTPPPDFAQCR------SASGSmNPmps-----mlSPPF------NTRVALQQNSVNLATEQNhg-cDNQQDRMdF 321
CAG00332     267 PPPPSTPPPDFSQCM------MGSTH----------------FlplafpSHHL--------------------------- 297
2_pfamImport   1 P----TPPPDFNQCV------MGSSH----------------FlplpfpNHRLADQQNSDNMAAEKNkm-aAAAAEEVtL 53 
2K7M_A        64 IHTQ-YGQK------PEQPSGAsagHRFPQGYH-------------------------------------SDKRRLSK-- 97 
XP_007251416 344 LKMS-FSQEp-----TDVPNSCappPLLNNGFL-------------------------------------SDKRRFSKss 380
AAI63086     324 LS---FSQTp-----TETPNSCaspSFLSSDF--------------------------------------EDKRRFSKss 357
XP_015219426 310 LQMS-YMQG------SDSSNTSap-pNLHNGFC-------------------------------------KDKRRLSKns 344
XP_006011654 323 IHVN-YEHN------KEASNSSvppLHLSHGFN-------------------------------------KDNRRLSKas 358
XP_005167744 346 LQMH-YGSPearvrsEMTPSTPstpS-SHPGFF-------------------------------------RDKRRLSKts 386
XP_005799418 330 LRIR-YEQLp-----AELPNGCsplPLLHSGFL-------------------------------------KDKRRLSRts 366
XP_011488177 322 LRIR-YEQGe-----AELPNRCspvSLLQAGYV-------------------------------------KDKRRLSRss 358
CAG00332     298 --MGcYSHG------WQKSNPS---QIQEDAYLrkdnncygpggrkmscpqiqnggsdrlllcpggalsqKDKRRFSKts 366
2_pfamImport  54 LQMSrYSPA------WPAAGGG---QIQDGGYLrtgdge--------------------------tggghRDRRRFSRts 98 
2K7M_A        98 -ASS-KARSDDLSV 109
XP_007251416 381 gSSS-RVRPDDLAV 393
AAI63086     358 gTSS-RMRPDDLAV 370
XP_015219426 345 gSSN-KLRVDDLAV 357
XP_006011654 359 kSSS-KGRSDDLAI 371
XP_005167744 387 gTSSnRLRPSDLAV 400
XP_005799418 367 gTSS-RARQDDLAV 379
XP_011488177 359 rTSS-RARQDDLAV 371
CAG00332     367 gTSS-RTRADDLSV 379
2_pfamImport  99 gTSS-RTRADDLSV 111
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