3U0G,3LUL


Conserved Protein Domain Family
Aminotran_4

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pfam01063: Aminotran_4 
Amino-transferase class IV
The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Statistics
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PSSM-Id: 395844
Aligned: 71 rows
Threshold Bit Score: 105.132
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3U0G_A             57 GVF---EGVR-AYktaDGGtaI----FR-LKEHTKRLLNSA-KIFq-M-------------DVPFDQETLEAAQRDVVRE 112
jgi:Bcen1808_2988  40 GVY---EVVP-VY---AHD--GahvpFR-IDQHLERLARSL-KKIg-I-------------DDPHDAPGWRALIERVVEA 94 
Q6Q938             32 SVY---EVIP-FF---NFK--A----IA-YKKHIHRLQNSC-NAL----------------GISINIESISSEITSLIKN 80  uncultured...
WP_011970057       31 AVY---EVTA-VI---GGR--M----ID-NDLHLGRLCRSL-KELa-I-------------PLALSLEQIAGIQAELIAR 81  Sinorhizob...
WP_008202654       31 GIF---DFFR-SV---NYK--P----LF-LDHYLDRFMSSAeKTF--L-------------PMPYSREDLKQIISDLTDK 81  Algoriphag...
tigr:CLI_2806      30 SLY---EVIR-II---DGV--P----LF-LKSHLNRFYNSA--KLegL-------------NLWLDEEVIKEKINRLIEI 80 
Q584G3             72 LLY---DLMR-VR---NGQ--V----MF-ENDHFSRIRQNCiLTAptAcdaanvsededlgKLSTYIEGVRSTTRDFIKC 137 Trypanosom...
Q4Q2V9            127 LVY---DVMR-SR---NGH--I----LF-KKSYAERFTHSLaLAA----------------PVHALPAQLRSLVQSRLQA 176 Leishmania...
XP_001707745       37 GAYtrfCTVH------RDR--I----LY-LAEHVTRLRKSLlGMLddR-------------YVELYHLSIPNMSKHRQEA 90 
Q8IKP7             27 GVY---TTMKtVM---SPE--Y----IFnFSLHMNNLHKYCtNYLkvQ-------------ENDTNREHISKILKYLTVE 81  Plasmodium...
3U0G_A            113 NKLESc---------yLRPIIWIGSEKLGv---------SAKGNTIHVAIAAWPWGAYlgeeglAKGIrvkt-------- 166
jgi:Bcen1808_2988  95 NAPGLgdg-----halVYLQVTRGVAKRGha------fpAHAVPTVFAMTSPLRLPSA------EERArgv--------- 148
Q6Q938             81 SRLENg---------yIYYQISRGIDALRshm-----yeDSLDEETFGYAVEHNFNSQ------TLKVs----------- 129 uncultured...
WP_011970057       82 NDLRDg---------tVYLQVSRGEADRDfl------ysEALAPKLVGFTQAKMLSGT------RAQRdgi--------- 131 Sinorhizob...
WP_008202654       82 NDMEQg---------gFRMVLSGGLSDNHf---------SPADGKLFIFPEELLFPSE------EKYNngi--------- 128 Algoriphag...
tigr:CLI_2806      81 NKVSIg---------nIKLVFNFNK---------------EKNNKFLCYFLKHNYPED------IEYKngvrt------- 123
Q584G3            138 NPWENgd-------vnLKFVTWVLPSQLSdvstaerrseLLRTLSYAVYYVTSFFPPE------DWYEegt--------- 195 Trypanosom...
Q4Q2V9            177 YIESPgvyldgaternVKLLSWIPATAASttq-----eeAFPIPGIVMLVKSSYPSES------MYREgak--------- 236 Leishmania...
XP_001707745       91 EDKFTea--------fLAEYMIKAADCMLkq-------iPTGDIRVDVHLSAYEPGFP------MFALgtpvp------- 142
Q8IKP7             82 DIYKNsskn---iktgFEYLNNLQNDLKNk---------HFSDNSNYMVMITLTWDMN------STVDtlekyysilcyi 143 Plasmodium...
3U0G_A            167 ------ssfTRHHVNVSMVRAKASGwYVNSILANQEATADG-----YD---EALLLDVDGy---VSEGSGENF-FLVN-- 226
jgi:Bcen1808_2988 149 ------rcvTAEDRRWLHCDIKSIS-LLGNVLMAQHAAERD-----AF---ETI-QLRDGn---VTEGSSSNV-WIVK-- 206
Q6Q938            130 ---------LCEDIRWQRCDIKSTS-LLGNVLSMNQAKKDG-----CN---EVI-MHKANl---LTEGGASNI-FFAT-- 184 uncultured...
WP_011970057      132 ------avdLADDPRWKRRDIKTAM-LLGQVMAKQAARARG-----FD---DVW-LVENGl---VTEGASSTAhVITA-- 190 Sinorhizob...
WP_008202654      129 -------klLSLEYVRPIAEIKTTN-YALAVWDSIRWKKEG-----AE---DVL-YHLNGq---VSESSRSNF-YIVK-- 185 Algoriphag...
tigr:CLI_2806     124 ----ilyhgERENPN-----AKVIN-MDFRKAVGEKIKEEK-----AY---EAILVDKNGy---ITEGSKSNI-FMIK-- 179
Q584G3            196 ------ryaMLYDAQRHTPNAKILQ-VPLRERAKALQQTTN-----AF---EVLLVSDNRrhylVPEGSRSNY-LIVS-- 257 Trypanosom...
Q4Q2V9            237 -------lgLLFNAHRTNPNAKVAQ-MGLRDRANAYLAEND-----VY---EVLLVHDAAdaylVPEGSRSNYlLQKS-- 298 Leishmania...
XP_001707745      143 -----nqdeTKDTVILERGERRTPT-IKDTQWIKERKPLESflgdtVE---EVVLMDDEGy---LYEGISSNFfVLLRrd 210
Q8IKP7            144 kclpkhqdhVQIDMMCGERKTPNIK-YADVFQVRDKFLKLK-----NEnshEVVLFNESNq---ITEGLSCNF-FCFL-- 211 Plasmodium...
3U0G_A            227 RGKLYTP--DLAS--CLDGITRDTVITLakeaGIe-VIEKRITRDEVYTADEAFFTGTAAEVTPIREL 289
jgi:Bcen1808_2988 207 NGELFAP--PRSNr-ILEGIRYALLEQLadecEVr-FVAREISEVELRAADEIMLTSATKEILPVTSL 270
Q6Q938            185 DDCIYTP--SLANn-ILPGITRELLIEEirnlGLn-FEEGDYNVEELSSAKSIWLTSSTKGLAQVTEI 248 uncultured marine gamm...
WP_011970057      191 EGHILTR--AASHv-TLPGCTQRALAKLcaaeGLq-IVERAFAPGEAQAAAEAFQTSASSLVTPVVRI 254 Sinorhizobium medicae
WP_008202654      186 DGVLITP----DQn-ILLGITRKHVLQLad-----kVEIRPLSMEETLAADEAFISSTTKVLLPVTQI 243 Algoriphagus machipong...
tigr:CLI_2806     180 DSKVITS--PVEK--VLPGITRQNIIDVcknlNLd-IDEEKVHYKDIEKLEGLFISGTSPKVLPIKSV 242
Q584G3            258 GDESLLC--SLEEd-ILVGITLRVARRAaacaRLppLRHRKLVLGDICLAKSIAMLGTSPGVLPIKEI 322 Trypanosoma brucei
Q4Q2V9            299 DGTWWCS---AEEd-ILVGITLKTTYRVvqacGLgsVQHAKLTLKDILESKSLFILGTSPTIMPVQSV 362 Leishmania major
XP_001707745      211 DGALVLQ--TAEDeyVLRGTIRSMVLSTakdlNVl-VEMSRPRIADINKWIGVFITSTTRRVKPISRV 275
Q8IKP7            212 NNTLYTAkdEL----VLKGTIREQIINLcereNIk-LKKDFIDIKDIHKFEFSFICSTTRNILPIRKI 274 Plasmodium falciparum 3D7
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