2KR0


Conserved Protein Domain Family
RPN13_C

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pfam16550: RPN13_C 
UCH-binding domain
RPN13_C is a family of all-helical domains that forms the binding-surface for the proteasome-ubiquitn-receptor protein Rpn13 to UCH37, one of the three de-ubiquitinating enzymes of the proteasome.
Statistics
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PSSM-Id: 465170
Aligned: 50 rows
Threshold Bit Score: 74.5959
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2KR0_A       278 MNVPAGPAG-GQQVDLASVLTPEIMAPIL-ANADVQERLLPYLPsgE----SLPQTA----DEIQNTLTSPQFQQALGMF 347
XP_002184709 250 MQQQTGAATpTVGPPLDQVVTPQAMDRLMdNEAA-RGRLVALLP--E-----GQQTP----EALRENLRSPQIQQTLRAL 317
A0DSE9       154 LQQQLTSRI-GPGLSLTDLLTTEFLTQIA-KDQEYFEALKEHLP--P-----DQQNL----EQFRENLLSPQFKQALDQL 220 Paramecium tetr...
Q22XT3       198 YQQRQ-----RDTPNFFEVLTKESLMELA-NDEEVQKELIQHLP--E-----GQQDV----QNLKENLISPQFQQALESL 260 Tetrahymena the...
CCG83233     273 IQVPPQETTqSESIDLQDVLTPDLILPLLaNEDT-RKSLFPHLP--Ssl-iSDPPTE----SEVRTIMTSVQWRQALSAL 344
ELU44038     154 LQGHSRAGV-APDVALSDILTPSILATVL-QDSEVVNSLTQFLP--VellsSPYATQvplqEVMKQTVASAPFRSSVRSL 229
Q5KH20       181 WARGGALGQpEDDARLTDVLSPSNISALIsSDPALISTITPLLP--PglslPENPTA----EDITPILSAPQFTDAIASL 254 Cryptococcus ne...
EKM79416     206 MANT------LPELALTDILSPTNIAPLFsSHPELLPALYHHLP--Pd--lPTPPSP----ETLQRVISSPQFRGAVSSF 271
XP_007845672 165 RLGAQGSSS-VPDLALTDILTPANISPLFtSHPELIPSLFPHLP--Pd--lPMPPSE----EVLQQVVNSPQFRAAVSNF 235
EPB82008     217 VRPAVEA---SAPIALSDILTTQSLTPLL-NDPEICASLFPFLP--E----ESERSA----EEVRQVVKSPQFSQALQSL 282
2KR0_A       348 SAAL------ASGQL-GPLMCQFGLPAE---AVEAANKGDVEAFAKAM 385
XP_002184709 318 TQALlpddegNTDGF-YSVLANFQLDPAhgqDALTQHNNPIQAFLDAL 364
A0DSE9       221 THAL------K-GRErSSVIQQLDLDYR----ILEQEFDGVIAFVKAI 257 Paramecium tetraurelia
Q22XT3       261 EKAL------NSNEG-GAVLASLGLDQS----NFMETLDGSDSFYKAI 297 Tetrahymena thermophila SB210
CCG83233     345 SYAL------NHGG--EPVIRSLGLDTS-----NLQGNSGVEAFLRAv 379
ELU44038     230 DQAL------STGLL-GGLVTSLGMPVE--------AGLGIHPFLEAI 262
Q5KH20       255 DNAL------RSGGLpGGMMRELGLPES--------AGSSVKGFLDgl 288 Cryptococcus neoformans
EKM79416     272 DQGL------QTGLL-GGFVRSFGLPEE--------AGIGILPFLRAI 304
XP_007845672 236 DQAL------RTGLL-GGLVRGLGLPEE--------AGLGIEPFLRAI 268
EPB82008     283 GAAL------QTGQL-GPLLSQLGLDPS--------AGNSVESFLIAI 315
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