GEO DataSets

(Submitter supplied) Atherosclerosis is the most important mechanism of cardiovascular and cerebrovascular diseases and has become one of the most serious diseases that threaten human health. Vascular smooth muscle cells (VSMCs) are the main cellular components that constitute the structure of the blood vessel wall. The excessive proliferation and migration are pivotal pathological basis of atherosclerosis, in-stent restenosis, pulmonary hypertension and other vascular proliferative diseases. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23178

6 Samples

Download data: CEL, XLSX

(Submitter supplied) Calcific aortic valve disease (CAVD) is the most common valvular heart disease in the aging population, ranging from initial aortic valve sclerosis to advanced aortic valve stenosis (AVS), but its underlying mechanism remains poorly understood. The present study aimed to explore the differentially expressed long non-coding RNAs and genes in CAVD.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL23178

4 Samples

Download data: CEL, CHP, TXT

(Submitter supplied) To elucidate the biological functions of lncRNA DUXAP9 in the process of oral squamous carcinogenesis and progression, and to evaluate its potential as a clinical predictive biomarker and therapeutic target,and toinvestigate the mechanism on how lncRNA DUXAP9 regulates EZH2,we screened lncRNAs differentially expressed in OSCC

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23178

18 Samples

Download data: CEL

(Submitter supplied) Atherosclerotic plaques belong to the common vascular disease in the aged, which rupture will lead to acute thromboembolic diseases, the major reason for fatal cardiovascular events. Accumulating evidence indicates that lncRNAs exert critical functions in atherosclerosis. To identify novel astherosclerotic plaques-relevant lncRNAs, four specimens of carotid atherosclerotic plaque were collected, and endovascular tissue one centimeter far from the carotid atherosclerotic plaque was taken as a control group, we performed lncRNA microarray analysis using Affymetrix Human OElncRNA

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23178

8 Samples

Download data: CEL

(Submitter supplied) Long non-coding RNAs (lncRNAs) can not only regulate gene transcription and translation, but also participate in the development of central nervous system diseases as epigenetic modification factors. However, their functional significance in atherosclerosis-induced ischemic stroke (AIIS) is unclear. The study aimed to screen out differentially expressed lncRNAs (delncRNAs), and to elucidate their potential regulatory mechanisms in the pathophysiology of AIIS. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23178

20 Samples

Download data: CEL

(Submitter supplied) Sepsis represents a complex disease with dysregulated inflammatory response and high mortality rate. Long noncoding RNAs (lncRNAs) have been reported to play regulatory roles in a variety of biological processes. However, studies evaluating the function of lncRNAs in pediatric sepsis are scarce, and current knowledge of the role of lncRNAs in pediatric sepsis is still limited. We explored the expression patterns of both lncRNAs and mRNAs between pediatric sepsis patients and healthy controls based on a comprehensive microarray analysis.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL23178

22 Samples

Download data: CEL

(Submitter supplied) Circulating transcriptional landscapes between BCSCs and non-BCSCs were compared using the Affymetrix Human OE LncRNA Microarray with probes for profiling of 63542 human lncRNAs. Goal was to investigate potential lncRNAs involved in BCSCs progression.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23178

2 Samples

Download data: CEL

(Submitter supplied) Circulating transcriptional landscapes between breast cancer tissues and adjacent normal tissues were compared using the Affymetrix Human OE LncRNA Microarray with probes for profiling of 63542 human lncRNAs. Goal was to investigate potential lncRNAs involved in breast cancer progression.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23178

6 Samples

Download data: CEL

(Submitter supplied) lncRNAs were associated with the cardiovascular diseases since we used Affy lncRNA gene expression microarray to analyze differentially expressed lncRNAs in both normal and Ang II induced HUVECs

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL23178

6 Samples

Download data: CEL, CHP, TXT

(Submitter supplied) The aim of this study was tantamount to screen and analyze the differential expression profiles of lncRNAs in ESCC, as well as to analyze the differentially expressed lncRNAs function and related acting molecules to further understand the role of lncRNAs in the occurrence and development of ESCC.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platform:

GPL23178

10 Samples

Download data: CEL

(Submitter supplied) cGAS-STING expression in HEK293T cells could up regulate a series of genes. Above them, Vpx significantly suppressed the NF-κB activated genes but had only a slight influence on the IRF3-activated genes. Diverse HIV-2 and SIV Vpx proteins showed an ability to inhibit DNA sensing-activated innate immune responses, suggesting an evolutionarily conserved function for Vpx.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23178

12 Samples

Download data: CEL

(Submitter supplied) External auditory canal squamous cell carcinoma (EACC) is very rare, only accounting for two thousandth of the head and neck cancer. However, the development mechanism of EACC remains unknown. By using gene expression microarray analysis, we aimed to find differentially expressed genes involved in ESCC development. We identified a wide spectrum of molecular signatures in EACC, including mRNA and lncRNA. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23178

16 Samples

Download data: CEL

(Submitter supplied) To investigate the long noncoding RNA (lncRNA) expression profiles in human apheresis platelet during the storage, and predict the potential biological function of lncRNAs in the process of platelet storage lesion. LncRNAs profiles of platelets were tested by Agilent Human lncRNA Array at 2nd, 5th, and 8th day during storage. Seven lncRNAs and four mRNAs were chosen to validate by real-time PCR, the result was consistent with the microarray. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array; Expression profiling by array

Platform:

GPL23178

9 Samples

Download data: CEL