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| Status |
Public on Feb 14, 2020 |
| Title |
Long noncoding RNA and messenger RNA abnormalities in pediatric sepsis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
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| Summary |
Sepsis represents a complex disease with dysregulated inflammatory response and high mortality rate. Long noncoding RNAs (lncRNAs) have been reported to play regulatory roles in a variety of biological processes. However, studies evaluating the function of lncRNAs in pediatric sepsis are scarce, and current knowledge of the role of lncRNAs in pediatric sepsis is still limited.
We explored the expression patterns of both lncRNAs and mRNAs between pediatric sepsis patients and healthy controls based on a comprehensive microarray analysis.
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| Overall design |
Total RNA was extracted using RNAiso (TaKaRa, Dalian, China) from the 10 septic children and 12 controls. Affymetrix Human oelncRNA Array (v1.0) was used to detect the expression of lncRNAs and mRNAs in the septic and control groups.
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| Contributor(s) |
Fang F, Bai Z |
| Citation(s) |
32151258 |
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| Submission date |
Feb 13, 2020 |
| Last update date |
Nov 10, 2021 |
| Contact name |
Fang Fang |
| E-mail(s) |
[email protected]
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| Phone |
86051280691513
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| Organization name |
Children’s Hospital of Soochow University
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| Street address |
92 Zhongnan street
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| City |
Suzhou |
| State/province |
Jiangsu |
| ZIP/Postal code |
215025 |
| Country |
China |
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| Platforms (1) |
| GPL23178 |
[OElncRNAs520855F] Affymetrix Human Custom lncRNA Array |
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| Samples (22)
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| GSM4308665 |
blood, control04 |
| GSM4308666 |
blood, control05 |
| GSM4308667 |
blood, control06 |
| GSM4308668 |
blood, control07 |
| GSM4308669 |
blood, control08 |
| GSM4308670 |
blood, control09 |
| GSM4308671 |
blood, control10 |
| GSM4308672 |
blood, control11 |
| GSM4308673 |
blood, control12 |
| GSM4308674 |
blood, sepsis01 |
| GSM4308675 |
blood, sepsis02 |
| GSM4308676 |
blood, sepsis03 |
| GSM4308677 |
blood, sepsis04 |
| GSM4308678 |
blood, sepsis05 |
| GSM4308679 |
blood, sepsis06 |
| GSM4308680 |
blood, sepsis07 |
| GSM4308681 |
blood, sepsis08 |
| GSM4308682 |
blood, sepsis09 |
| GSM4308683 |
blood, sepsis10 |
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| Relations |
| BioProject |
PRJNA606469 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE145227_RAW.tar |
247.3 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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