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Items: 2

1.

Infection with bradyzoites has a diminished impact on host transcript levels relative to tachyzoite infection.

(Submitter supplied) 5 arrays per condition (covering 3 biological replicate experiments) were performed on Human Foreskin Fibroblasts (HFFs) at 44 hours post infection. The four experimental conditions include uninfected "standard", uninfected "stress", tachyzoite-infected "standard+TZ", and bradyzoite-infected "stress+BZ". Bradyzoite conversion is induced at 4 hours post infection with replacement of standard DMEM+10% FCS with RPMI+1%FCS buffered with 50mM Hepes to pH 8.15. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
4 related Platforms
20 Samples
Download data
Series
Accession:
GSE8773
ID:
200008773
2.

Mechanism of the anti-inflammatory effect of colchicine in rheumatic diseases

(Submitter supplied) Objective. Colchicine is an alkaloid that is used to alleviate acute gout and to prevent acute attacks of familial Mediterranean fever (FMF). However, it is not beneficial when given during the occurrence of an acute episode of FMF. It is believed that colchicine exerts its anti-inflammatory effect through direct interaction with microtubules. We aim to study the molecular basis of colchicine action by analysing the effect of this drug on global gene expression of HUVEC (human umbilical vein endothelial cell line) cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1753
Platform:
GPL3386
16 Samples
Download data
Series
Accession:
GSE4090
ID:
200004090

Supplemental Content

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