GEO DataSets

(Submitter supplied) Previous studies have shown that the MpeR transcriptional regulator produced by Neisseria gonorrhoeae represses expression of mtrF, which encodes a putative inner membrane protein that works with the MtrC-MtrD-MtrE efflux pump to allow gonococci to resist high levels of multiple hydrophobic antimicrobials. Regulation of mpeR has been reported to occur by an iron-dependent mechanism involving Fur (Ferric uptake regulator). more...

Organism:

Neisseria gonorrhoeae

Type:

Expression profiling by array

Platform:

GPL7218

12 Samples

Download data: CEL, TXT

(Submitter supplied) Naturally occurring mtrR mutants of gonococci displaying clinically relevant levels of antibiotic resistance are often isolated from patients and mtrR mutants have been reported to be more fit than the wild type parent strain in a murine vaginal infection model. DNA-binding proteins, such as MtrR, that negatively regulate bacterial efflux pump genes have been considered to be “local” gene regulators, although there is increasing evidence that they can directly or indirectly influence expression of other genes. more...

Organism:

Neisseria gonorrhoeae

Type:

Expression profiling by array

Platform:

GPL7218

6 Samples

Download data: CEL, TXT

(Submitter supplied) Affymetrix;Custom multipathogen array

Organism:

Neisseria gonorrhoeae

2 Series

15 Samples

Download data