|
| Status |
Public on Dec 26, 2008 |
| Title |
Expression data from Neisseria gonorrhoeae (FA19) |
| Organism |
Neisseria gonorrhoeae |
| Experiment type |
Expression profiling by array
|
| Summary |
Naturally occurring mtrR mutants of gonococci displaying clinically relevant levels of antibiotic resistance are often isolated from patients and mtrR mutants have been reported to be more fit than the wild type parent strain in a murine vaginal infection model. DNA-binding proteins, such as MtrR, that negatively regulate bacterial efflux pump genes have been considered to be “local” gene regulators, although there is increasing evidence that they can directly or indirectly influence expression of other genes. To define the regulatory properties of MtrR we employed microarray analysis of isogenic MtrR-positive and MtrR-negative gonococci.
Keywords: single time point
|
| |
|
| Overall design |
RNA was isolated at mid-log growth for expression analysis
|
| |
|
| Contributor(s) |
Jackson L, Dyer D, Folster J, Johnson P, Dhulipali V, Shafer W |
| Citation(s) |
18978065 |
| |
| Submission date |
Sep 05, 2008 |
| Last update date |
Apr 05, 2012 |
| Contact name |
Lydgia Jackson |
| E-mail(s) |
[email protected], [email protected]
|
| Phone |
405 271-1201
|
| Fax |
405 271-1204
|
| Organization name |
University of Oklahoma Health Sciences Center
|
| Department |
Microbiology and Immunology
|
| Lab |
David Dyer
|
| Street address |
975 NE 10th Street
|
| City |
Oklahoma City |
| State/province |
OK |
| ZIP/Postal code |
73104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL7218 |
OUHSC_Neisseria gonorrhoeae_MPAUT1a520274F |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA112689 |
Less...
More...