GEO DataSets

(Submitter supplied) Oxidative stress is a common factor threating genomic stability in almost all aerobic organisms. Using a yeast screening system, we measured the frequency of mitotic recombination was greatly elevated after H2O2 treatment. H2O2 was able to break chromatid directly in G1 synchronized cells and homologous recombination was induced to repair DNA double stand breaks at S/G2 phase. By whole genome SNP microarray and sequencing, the patterns of H2O2 induced loss of heterozygosity (LOH; gene conversion and crossover), chromosomal rearrangement, and aneuploidy changes were revealed. more...

Organism:

Saccharomyces cerevisiae

Type:

Genome variation profiling by SNP array

Platforms:

GPL21552 GPL20144 GPL21553

169 Samples

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(Submitter supplied) S288c vs YJM789 SNPs chromosome 4. Protocol: see manufacturer's web site at http://www.agilent.com/

Organism:

Saccharomyces cerevisiae

5 Series

1 Related Platform

226 Samples

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(Submitter supplied) see manufacturer's web site at http://www.agilent.com/

Organism:

Saccharomyces cerevisiae

8 Series

1 Related Platform

390 Samples

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(Submitter supplied) Whole genome SNPs between S288c and YJM789. Both Watson and Crick strands represented as well as both probes specific to both strains. In the labels of the oligonucleotides 'SF', 'SR', 'YF' and 'YR' refer to the orientation and origin of the sequences used for the oligonucleotides on the microarrays. 'S' and 'Y' indicate whether the oligonucleotide contains sequences identical to the reference S288c genome (closely related to W303-1A) or the YJM789 genome, respectively. more...

Organism:

Saccharomyces cerevisiae

13 Series

1 Related Platform

367 Samples

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