GSE11229[Accession] - GEO DataSets - NCBI

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Items: 14

Select item 2000112291.

Dicer-null cell lines vs. wt ES cells and Dicer-null cell lines vs. Dicer-null cells overexpressing Dnmt1 or Dnmt3a/3b

(Submitter supplied) Dicer initiates RNA interference by generating small RNAs involved in various silencing pathways. Dicer participates in centromeric silencing, but its role in the epigenetic regulation of other chromatin domains has not been explored. Here we show that Dicer1 deficiency in Mus musculus leads to decreased DNA methylation, concomitant with increased telomere recombination and telomere elongation. These DNA-methylation defects correlate with decreased expression of Dnmt1, Dnmt3a and Dnmt3b DNA methyltransferases (Dnmts), and methylation levels can be recovered by their overexpression. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL4134
12 Samples

Download data: TXT

Series

Accession:: GSE11229

ID:: 200011229

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000041342.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...

Organism:: Mus musculus

7 DataSets
603 Series
1 Related Platform
7491 Samples

Download data: TXT

Platform

Accession:: GPL4134

ID:: 100004134

Select item 3002831183.

Dicer1-null 27H10 versus wild-type ES cells 2

Organism:: Mus musculus

Source name:: DicerNull27 h10 (channel 1) wtEstCells (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283118

ID:: 300283118

Select item 3002831174.

Dicer1-null 27G5 versus wild-type ES cells 2

Organism:: Mus musculus

Source name:: DicerNull27 g5 (channel 1) wtEstCells (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283117

ID:: 300283117

Select item 3002831165.

Dicer1-null 27H10 versus wild-type ES cells 1

Organism:: Mus musculus

Source name:: wtEstCells (channel 1) DicerNull27 h10 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283116

ID:: 300283116

Select item 3002831156.

Dicer1-null 27G5 versus wild-type ES cells 1

Organism:: Mus musculus

Source name:: wtEstCells (channel 1) DicerNull27 g5 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283115

ID:: 300283115

Select item 3002831147.

Dicer1-null 27H10 overexpressing Dnmt3a,3b versus Dicer1-null 27H10 cells 2

Organism:: Mus musculus

Source name:: 27H10+DNMT3a,3b (channel 1) Dicer Null 27H10 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283114

ID:: 300283114

Select item 3002831138.

Dicer1-null 27H10 overexpressing Dnmt3a,3b versus Dicer1-null 27H10 cells 1

Organism:: Mus musculus

Source name:: Dicer Null 27H10 (channel 1) 27H10+DNMT3a,3b (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283113

ID:: 300283113

Select item 3002831129.

Dicer1-null 27H10 cells overexpressing Dnmt1 versus Dicer1-null 27H10 cells 2

Organism:: Mus musculus

Source name:: 27H10+DNMT1 (channel 1) Dicer Null 27H10 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283112

ID:: 300283112

Select item 30028311110.

Dicer1-null 27H10 cells overexpressing Dnmt1 versus Dicer1-null 27H10 cells 1

Organism:: Mus musculus

Source name:: Dicer Null 27H10 (channel 1) 27H10+DNMT1 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283111

ID:: 300283111

Select item 30028311011.

Dicer1-null 27G5 cells overexpressing Dnmt3a,3b versus Dicer1-null 27G5 cells 2

Organism:: Mus musculus

Source name:: 27 g5+DNMT3a,3b (channel 1) Dicer Null 27G5 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283110

ID:: 300283110

Select item 30028310912.

Dicer1-null 27G5 cells overexpressing Dnmt3a,3b versus Dicer1-null 27G5 cells 1

Organism:: Mus musculus

Source name:: Dicer Null 27G5 (channel 1) 27 g5+DNMT3a,3b (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283109

ID:: 300283109

Select item 30028310813.

Dicer1-null 27G5 cells overexpressing Dnmt1 versus Dicer1-null 27G5 cells 2

Organism:: Mus musculus

Source name:: 27 g5+DNMT1 (channel 1) Dicer Null 27G5 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283108

ID:: 300283108

Select item 30028310714.

Dicer1-null 27G5 cells overexpressing Dnmt1 versus Dicer1-null 27G5 cells 1

Organism:: Mus musculus

Source name:: Dicer Null 27G5 (channel 1) 27 g5+DNMT1 (channel 2)

Platform:: GPL4134
Series:: GSE11229

Download data: TXT

Sample

Accession:: GSM283107

ID:: 300283107

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