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Items: 20

1.

129-derived passenger mutations confound phenotype of ACKR1-deficient mice

(Submitter supplied) A majority of genetically modified mice carry passenger mutations, originating from the 129-derived embryonic stem (ES) cells, near the targeted gene. Unintended retention of these mutations can introduce confounding phenotypes and affect conclusions. We show that Ackr1-/-129ES mice retained approximately 6 Mb of 129 ES cells-derived genomic material in chromosome 1 near Ackr1 in bone marrow derived monocytes (Mono), nucleated erythroblasts (NECs), and polymorphonucleated neutrophils (PMN), notably affecting the expression of PYHIN genes.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL20775
18 Samples
Download data: CEL
Series
Accession:
GSE256021
ID:
200256021

PubMed Analyze with GEO2R

2.

[MTA-1_0] Affymetrix Mouse Transcriptome Array 1.0 [transcript (gene) CSV version]

(Submitter supplied) Annotation was derived from the Affymetrix annotation file MTA-1_0.na35.mm10.transcript.csv: #%create_date=Wed Apr 1 16:56:09 2015 PDT #%chip_type=MTA-1_0 #%lib_set_name=MTA-1_0 #%lib_set_version=r1 #%genome-species=Mus musculus #%genome-version=mm10 #%genome-version-ucsc=mm10 #%genome-version-ncbi=38 #%genome-version-create_date=2011-12-00 #%genome-lifted-method=psl-map.pl #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm10 #%genome-lifted_from-version-ncbi=38 #%netaffx-annotation-date=2014-10-31 #%netaffx-annotation-netaffx-build=35 Protocol: See manufacturers website
Organism:
Mus musculus
201 Series
2 Related Platforms
2254 Samples
Download data
Platform
Accession:
GPL20775
ID:
100020775

3.

BM_KO2_PMN

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084271
ID:
308084271

4.

BM_KO2_NEC

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084270
ID:
308084270

5.

BM_KO1_Mono

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084269
ID:
308084269

6.

BM_KO1_NEC

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084268
ID:
308084268

7.

BM_WT3_Mono

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084267
ID:
308084267

8.

BM_WT3_PMN

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084266
ID:
308084266

9.

BM_WT3_NEC

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084265
ID:
308084265

10.

BM_KO5_Mono

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084264
ID:
308084264

11.

BM_KO5_PMN

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084263
ID:
308084263

12.

BM_KO5_NEC

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084262
ID:
308084262

13.

BM_KO4_PMN

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084261
ID:
308084261

14.

BM_KO3_Mono

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084260
ID:
308084260

15.

BM_WT4_NEC

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084259
ID:
308084259

16.

BM_WT2_Mono

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084258
ID:
308084258

17.

BM_WT2_PMN

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084257
ID:
308084257

18.

BM_WT2_NEC

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084256
ID:
308084256

19.

BM_WT1_Mono

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084255
ID:
308084255

20.

BM_WT1_PMN

Organism:
Mus musculus
Source name:
bone marrow
Platform:
GPL20775
Series:
GSE256021
Download data: CEL
Sample
Accession:
GSM8084254
ID:
308084254

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