GEO DataSets

(Submitter supplied) Normal cells require continuous exposure to growth factors, in order to cross a restriction point and commit to cell cycle progression. This can be replaced by two short, appropriately spaced pulses of growth factors, where the first pulse primes a process, which is completed by the second pulse, and enables restriction point crossing. Through integration of comprehensive proteomic and transcriptomic analyses of each pulse, we identified three processes that regulate restriction point crossing: (i) The first pulse induces essential metabolic enzymes and activates p53-dependent restraining processes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4362

Platform:

GPL6244

17 Samples

Download data: CEL

Analysis of 184A1 mammary epithelial cells pulsed once or twice with epidermal growth factor (EGF). Normal cells require continuous exposure to growth factors to cross a restriction point and commit to cell-cycle progression. Results provide insight into molecular events regulating S phase entry.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 protocol, 13 time sets

Platform:

GPL6244

Series:

GSE27629

17 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Homo sapiens

136 DataSets

1879 Series

27 Related Platforms

38399 Samples

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