GEO DataSets

(Submitter supplied) In mammalian cells, AU-rich elements (AREs) are well known regulatory sequences located in the 3' untranslated region (UTR) of many short-lived mRNAs that suppress gene expression at the posttranscriptional level. Tis11, a zinc finger RNA-binding protein homologous to mammalian tristetraprolin, targets ARE-containing reporter mRNAs for rapid degradation in SL2 cells. To identify Drosophila mRNA targets of Tis11, we performed genome-wide expression profiling after dsRNA-mediated depletion of endogenous Tis11 in SL2 cells. more...

Organism:

Drosophila melanogaster

Type:

Expression profiling by array

Platform:

GPL1322

12 Samples

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(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 July 06, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Drosophila Genome 2.0 Array is a microarray tool for studying expression of Drosophila melanogaster transcripts: - Provides comprehensive coverage of the transcribed Drosophila genome on a single array - Comprised of 18,880 probe sets, analyzing over 18,500 transcripts Sequences used in the design of the GeneChip Drosophila Genome 2.0 Array were selected from Flybase version 3.1. more...

Organism:

Drosophila melanogaster

25 DataSets

362 Series

1 Related Platform

5224 Samples

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