GEO DataSets

(Submitter supplied) Tha altered biological pathways in Epidermolysis bulloda simplex, a rare monogenetic skin disease, have not been well characterized. Thus, the goal of this study is to characterize the expression profile of EBS patients compared with normal subjects using genomic expression analyses. Microarray analyses were performed with RNA isolated from skin biopsies. Robust multiarray analysis (RMA) normalization and Smyth’s moderated t test were used to select differentially expressed genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS4426

Platform:

GPL6244

12 Samples

Download data: CEL

Analysis of epidermal punch biopsies (with minimal dermis amounts) from six EBS patients. Most EBS cases are caused by defects in the genes encoding intermediate filament proteins keratin 5 (KRT5) and keratin 14 (KRT14). Results provide further insight into the molecular basis of EBS.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state sets

Platform:

GPL6244

Series:

GSE28315

12 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 18, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Homo sapiens

136 DataSets

1879 Series

27 Related Platforms

38399 Samples

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