GEO DataSets

(Submitter supplied) Though expression of the homeobox transcription factor Nanog is generally restricted to pluripotent cells and early germ cells, recent reports have found that Nanog is re-expressed in somatic and germ cell tumors associated with poor differentiation and aggressive disease progression. To elucidate its oncogenic properties, a modified Tet-On system was utilised to generate Nanog-inducible mice. By dexamethasone and doxycycline injection, similar Nanog expression levels as in wild-type embryonic stem cells were obtained in all major organs except for brain. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS5376

Platform:

GPL6885

8 Samples

Download data: TXT

Analysis of colon and intestine cells with ectopic Nanog protein expression. Aggressive tumor progression and poor patient diagnosis have been associated with Nanog expression in different types of tumors. Results provide insight into the role of Nanog in tumor initiation.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 protocol, 2 tissue sets

Platform:

GPL6885

Series:

GSE31413

8 Samples

Download data

(Submitter supplied) The MouseRef-8 v2.0 Expression BeadChip offer the most up-to-date content for whole-genome expression profiling in the mouse. Featuring content derived from the National Center for Biotechnology Information Reference Sequence (NCBI RefSeq) database (Build 36, Release 22). Please use the GEO Data Submission Report Plug-in v1.0 for Gene Expression which may be downloaded from https://icom.illumina.com/icom/software.ilmn?id=234 to format the normalized and raw data. more...

Organism:

Mus musculus

33 DataSets

903 Series

16894 Samples

Download data: BGX