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(Submitter supplied) Moderate alcohol consumption during pregnancy can result in a heterogeneous range of neurobehavioural and cognitive effects, termed fetal alcohol spectrum disorders (FASD). We have developed a mouse moder of FASD that involves moderate ethanol exposure throughout gestation achieved by voluntary maternal consumption. This model results in phenotypes relevant to FASD. Since ethanol is known to directly affect the expression of genes in the developing brain leading to abnormal cell death, changes to cell proliferation, migration, and differentiation, and potential changes to epigenetic patterning, we hypothesize that this leaves a long-term footprint on the adult brain. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS4613

Platform:

GPL6246

10 Samples

Download data: CEL

Analysis of brain from adult (postnatal day 70) male offspring prenatally exposed to alcohol via voluntary maternal consumption from gestational day 0 to pup postnatal day 10. Results provide insight into molecular basis of long-term persistence of FASD-related cognitive and behavioral alterations.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 other, 2 protocol sets

Platform:

GPL6246

Series:

GSE34305

10 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: See manufacturer's web site

Organism:

Mus musculus

143 DataSets

2504 Series

28 Related Platforms

30419 Samples

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