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Items: 1 to 20 of 51

1.

Tet enzymes are essential for embryogenesis and completion of embryonic genome activation

(Submitter supplied) Mammalian embryo development begins in transcriptional silence followed by activation of thousands of genes. Reprogramming of DNA methylation is integral to embryogenesis and linked to Tet enzymes; however, their function in early development is not fully understood. Here, we generated combined deficiencies of all three Tet enzymes in mouse oocytes and observed arrest at 2-cell stage with the most severe phenotype linked to Tet2. more...
Organism:
Mus musculus; synthetic construct
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL13112 GPL15228
48 Samples
Download data: TXT
Series
Accession:
GSE57063
ID:
200057063
2.

Illumina HiSeq 2000 (synthetic construct)

Organism:
synthetic construct
48 Series
1879 Samples
Download data
Platform
Accession:
GPL15228
ID:
100015228
3.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
4.

no RNA negative control_3

Organism:
synthetic construct
Source name:
no RNA
Platform:
GPL15228
Series:
GSE57063
Download data
Sample
Accession:
GSM1373905
ID:
301373905
5.

no RNA negative control_2

Organism:
synthetic construct
Source name:
no RNA
Platform:
GPL15228
Series:
GSE57063
Download data
Sample
Accession:
GSM1373904
ID:
301373904
6.

no RNA negative control_1

Organism:
synthetic construct
Source name:
no RNA
Platform:
GPL15228
Series:
GSE57063
Download data
Sample
Accession:
GSM1373903
ID:
301373903
7.

alpha-amanitin treated 2-cell embryo_12

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479697
ID:
301479697
8.

alpha-amanitin treated 2-cell embryo_11

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479696
ID:
301479696
9.

alpha-amanitin treated 2-cell embryo_10

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479695
ID:
301479695
10.

alpha-amanitin treated 2-cell embryo_9

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479694
ID:
301479694
11.

alpha-amanitin treated 2-cell embryo_8

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479693
ID:
301479693
12.

alpha-amanitin treated 2-cell embryo_7

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479692
ID:
301479692
13.

alpha-amanitin treated 2-cell embryo_6

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479691
ID:
301479691
14.

alpha-amanitin treated 2-cell embryo_5

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479690
ID:
301479690
15.

alpha-amanitin treated 2-cell embryo_4

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479689
ID:
301479689
16.

alpha-amanitin treated 2-cell embryo_3

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479688
ID:
301479688
17.

alpha-amanitin treated 2-cell embryo_2

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479687
ID:
301479687
18.

alpha-amanitin treated 2-cell embryo_1

Organism:
Mus musculus
Source name:
alpha-amanitin treated 2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1479686
ID:
301479686
19.

Tet1-, Tet2-, Tet3-morpholino injected 2-cell embryo_11

Organism:
Mus musculus
Source name:
2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1373902
ID:
301373902
20.

Tet1-, Tet2-, Tet3-morpholino injected 2-cell embryo_10

Organism:
Mus musculus
Source name:
2-cell embryo
Platform:
GPL13112
Series:
GSE57063
Download data
Sample
Accession:
GSM1373901
ID:
301373901
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