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Items: 10

1.

A small molecule inhibitor of iron-sulfur cluster assembly is toxic to Staphylococcus aureus in an Sae-dependent manner

(Submitter supplied) VU0038882 ('882) is a small molecule compound with antistaphylococcal activity and increased activity toward the organism during anaerobic growth conditions. The mechanism of action of '882 is hypothesized to be saeRS dependent S. aureus Affymetrix GeneChips were used to compare the S. aureus expression properties of wild type and isogenic ΔsaeRS mutant cells in response to '882 challenge during anaerobic growth conditions. more...
Organism:
Staphylococcus aureus
Type:
Expression profiling by array
Platform:
GPL1339
8 Samples
Download data: CEL, CHP
Series
Accession:
GSE85379
ID:
200085379
2.

[S_aureus] Affymetrix S. aureus Genome Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 Oct 18, 2012: annotation table updated with netaffx build 32 Protocol: see manufacturer's web site For comprehensive monitoring of the relative mRNA abundance of S. aureus sequences. The GeneChip S. aureus Genome Array is useful for studying the expression of sequences in the following four strains of Staphylococcus aureus: N315 (National Institute of Technology and Evaluation, Japan), Mu50 (National Institute of Technology and Evaluation, Japan), NCTC 8325 (University of Oklahoma), and COL (TIGR). The array contains probe sets to over 3,300 S. aureus open reading frames. Additionally, the array also contains probes to study both forward and reverse orientation of over 4,800 intergenic regions throughout the S. aureus genome.
Organism:
Staphylococcus aureus
7 DataSets
55 Series
542 Samples
Download data
Platform
Accession:
GPL1339
ID:
100001339
3.

strain saeRS, anaerobic growth, '882 treated, rep 2

Organism:
Staphylococcus aureus
Source name:
Newman with ΔsaeRS_'882
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266040
ID:
302266040
4.

strain saeRS, anaerobic growth, '882 treated, rep 1

Organism:
Staphylococcus aureus
Source name:
Newman with ΔsaeRS_'882
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266039
ID:
302266039
5.

strain saeRS, anaerobic growth, DMSO treated, rep 2

Organism:
Staphylococcus aureus
Source name:
Newman with ΔsaeRS_DMSO
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266038
ID:
302266038
6.

strain saeRS, anaerobic growth, DMSO treated, rep 1

Organism:
Staphylococcus aureus
Source name:
Newman with ΔsaeRS_DMSO
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266037
ID:
302266037
7.

strain Newman, anaerobic growth, '882 treated, rep 2

Organism:
Staphylococcus aureus
Source name:
Newman_WT_'882
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266036
ID:
302266036
8.

strain Newman, anaerobic growth, '882 treated, rep 1

Organism:
Staphylococcus aureus
Source name:
Newman_WT_'882
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266035
ID:
302266035
9.

strain Newman, anaerobic growth, DMSO treated, rep 2

Organism:
Staphylococcus aureus
Source name:
Newman_WT_DMSO
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266034
ID:
302266034
10.

strain Newman, anaerobic growth, DMSO treated, rep 1

Organism:
Staphylococcus aureus
Source name:
Newman_WT_DMSO
Platform:
GPL1339
Series:
GSE85379
Download data: CEL, CHP
Sample
Accession:
GSM2266033
ID:
302266033
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Supplemental Content

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