GEO DataSets

(Submitter supplied) MicroRNAs (miRNAs) play important roles in cell differentiation and self-renewal controlling post-transcriptional processing of mRNAs and attenuating production of the encoded proteins. Here, we unveil a novel oncogenic pathway leading to activation of STAT3 signaling through miRNA-mediated silencing of the E3 ubiquitin ligase COP1. miRNA profiling showed that miR-424 was upregulated in prostate cancer compared to normal prostate and specifically associated with reduced level of the ETS factor ESE3/EHF in an aggressive subgroup of tumors. more...

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL13264

77 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL14550 GPL13264

219 Samples

Download data: TXT

(Submitter supplied) see manufacturer's web site at http://www.agilent.com/

Organism:

Homo sapiens

30 Series

1 Related Platform

535 Samples

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